Development Level

Tbio 25 | 10,625
Tchem 8 | 1,890
Tdark 6 | 7,003

IMPC Phenotype

abnormal retina morphology 2 | 100
abnormal skin coloration 2 | 18
decreased eosinophil cell numb... 2 | 41
pallor 2 | 13
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal foot plate morphology 1 | 2
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 31
decreased circulating serum al... 1 | 79
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased spleen weight 1 | 3
increased startle reflex 1 | 38
pale liver 1 | 5
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small adrenal glands 1 | 15
small superior vagus ganglion 1 | 20
small thymus 1 | 11

Disease

osteosarcoma 16 | 7,933
ovarian cancer 15 | 8,491
psoriasis 13 | 6,685
lung cancer 11 | 4,473
glioblastoma 10 | 5,572
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
atypical teratoid / rhabdoid tumor 7 | 4,369
cytochrome-c oxidase deficiency disease 7 | 19
lung adenocarcinoma 7 | 2,714
lung carcinoma 7 | 2,844
medulloblastoma, large-cell 7 | 6,234
non-small cell lung cancer 7 | 2,798
pediatric high grade glioma 7 | 2,712
Cytochrome-c Oxidase Deficiency 6 | 15
Multiple myeloma 6 | 1,327
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Atherosclerosis 5 | 275
Hypertension 5 | 293
adrenocortical carcinoma 5 | 1,427
astrocytoma 5 | 1,493
diabetes mellitus 5 | 1,663
invasive ductal carcinoma 5 | 2,950
Breast cancer 4 | 3,098
Chronic granulomatous disease 4 | 13
Kidney disease 4 | 397
Leigh disease 4 | 81
Mitochondrial complex IV deficiency 4 | 6
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
malignant mesothelioma 4 | 3,163
pancreatic cancer 4 | 2,300
pilocytic astrocytoma 4 | 3,086
primitive neuroectodermal tumor 4 | 3,031
sonic hedgehog group medulloblastoma 4 | 1,482
Atopic dermatitis 3 | 944
Cerebrovascular disease 3 | 231
Heart disease 3 | 279
Heart failure 3 | 80
Leigh syndrome 3 | 34
Neurodegenerative disease 3 | 383
Polycystic Ovary Syndrome 3 | 334
Rheumatoid Arthritis 3 | 1,170
Schizophrenia 3 | 503
breast carcinoma 3 | 1,614
cutaneous lupus erythematosus 3 | 1,056
inflammatory breast cancer 3 | 404
nephrosclerosis 3 | 329
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group A ependymoma 3 | 1,511
primary Sjogren syndrome 3 | 788
ulcerative colitis 3 | 2,087
Barrett's adenocarcinoma 2 | 2
Brain disease 2 | 84
Cardiomyopathies 2 | 90
Charcot-Marie-Tooth disease 2 | 74
Colonic Neoplasms 2 | 126
Endometriosis 2 | 535
Fascioliasis 2 | 18
Hypertrophic Cardiomyopathy 2 | 56
Hypothyroidism 2 | 89
IGA Glomerulonephritis 2 | 454
Kidney Failure, Chronic 2 | 45
Leber hereditary optic neuropathy 2 | 17
Liver Failure, Acute 2 | 22
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 2 | 9
Mitochondrial myopathy 2 | 24
Neuropathy 2 | 210
Obesity 2 | 616
Primary hyperoxaluria 2 | 16
Recurrent myoglobinuria mitochondrial 2 | 2
Schizoaffective disorder 2 | 33
Velocardiofacial syndrome 2 | 45
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
adult high grade glioma 2 | 2,148
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
ependymoma 2 | 2,514
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 550
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
uncontrolled asthma 2 | 67
Allergic conjunctivitis 1 | 25
Alopecia areata 1 | 37
Angioedema 1 | 36
Congenital myasthenic syndrome, acetazolamide-responsive 1 | 5
Epilepsy, Temporal Lobe 1 | 23
Microsporidiosis 1 | 12
Myasthenic Syndrome due to Mutation in SCN4A 1 | 5
Paragonimiasis 1 | 9
ariboflavinosis 1 | 5

Tissue

Blood and immune system 38 | 17,994
Digestive Tract 38 | 18,472
Endocrine System 38 | 18,511
Female tissues 38 | 18,646
Liver and Pancreas 38 | 18,135
Nervous System 38 | 18,560
Skin and soft tissues 38 | 18,114
Urinary Tract 38 | 18,443
Cardiovascular System 37 | 17,957
Male tissues 37 | 17,968
Respiratory system 37 | 17,483

Target Family

Enzyme 30 | 4,146
Non-IDG 8 | 11,969
Ion Channel 1 | 341

PANTHER Protein Class (1)

oxidase 39 | 39
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyridoxine-5'-phosphate oxidase PNPO Tchem Enzyme -1.92404 83.6 160
Cytochrome b5 type B CYB5B Tbio Non-IDG -0.89834 7.51 36
Proline dehydrogenase 1, mitochondrial PRODH Tbio Enzyme -2.85387 715.1 193
Cytochrome b-245 heavy chain CYBB Tchem Ion Channel -3.05146 1149.7 273
Cytochrome c oxidase subunit 7A2, mitochondrial COX7A2 Tdark Enzyme -0.92341 14.7 0
Probable proline dehydrogenase 2 PRODH2 Tbio Enzyme -0.72179 5.85 62
Dual oxidase 2 DUOX2 Tbio Enzyme -2.40297 227.0 112
Dual oxidase 1 DUOX1 Tbio Enzyme -2.45523 255.7 81
NADPH oxidase 4 NOX4 Tchem Enzyme -2.80427 658.6 332
Neutrophil cytosol factor 2 NCF2 Tbio Non-IDG -2.26289 195.4 134