Development Level
Tbio | 27 | 11,445 | |
Tchem | 8 | 1,598 | |
Tdark | 4 | 6,588 |
IMPC Phenotype
preweaning lethality, complete... | 3 | 979 | |
abnormal embryo size | 2 | 220 | |
abnormal placenta size | 2 | 20 | |
abnormal skin coloration | 2 | 25 | |
pallor | 2 | 34 | |
abnormal behavior | 1 | 298 | |
abnormal embryonic autopod pla... | 1 | 2 | |
abnormal limb bud morphology | 1 | 17 | |
abnormal liver size | 1 | 5 | |
abnormal placenta development | 1 | 1 | |
abnormal placenta morphology | 1 | 5 | |
abnormal sleep behavior | 1 | 70 | |
decreased caudal vertebrae num... | 1 | 53 | |
decreased circulating iron lev... | 1 | 32 | |
decreased circulating phosphat... | 1 | 27 | |
decreased erythrocyte cell num... | 1 | 62 | |
decreased hematocrit | 1 | 46 | |
decreased hemoglobin content | 1 | 68 | |
decreased mean corpuscular hem... | 1 | 50 | |
decreased mean corpuscular hem... | 1 | 31 | |
decreased mean corpuscular vol... | 1 | 79 | |
decreased total body fat amoun... | 1 | 207 | |
decreased vertical activity | 1 | 208 | |
embryonic growth retardation | 1 | 106 | |
hypoactivity | 1 | 132 | |
increased circulating glucose ... | 1 | 24 | |
increased fasted circulating g... | 1 | 76 | |
increased spleen weight | 1 | 10 | |
pale liver | 1 | 6 | |
prenatal lethality | 1 | 28 | |
prenatal lethality prior to he... | 1 | 87 |
Disease
Tissue
Endocrine System | 38 | 18,159 | |
Blood and immune system | 37 | 16,909 | |
Digestive Tract | 37 | 17,369 | |
Female tissues | 36 | 17,400 | |
Liver and Pancreas | 36 | 16,750 | |
Nervous System | 36 | 16,725 | |
Skin and soft tissues | 36 | 17,230 | |
Urinary Tract | 36 | 16,678 | |
Male tissues | 35 | 17,142 | |
Cardiovascular System | 33 | 15,192 | |
Respiratory system | 32 | 16,393 |
Target Family
Enzyme | 28 | 4,145 | |
Non-IDG | 10 | 12,091 | |
Ion Channel | 1 | 344 |
PANTHER Protein Class (1)
oxidase | 39 | 39 | |
protease | 516 | 516 | |
RNA binding protein | 483 | 483 | |
kinase | 362 | 362 | |
DNA binding protein | 342 | 342 | |
protease inhibitor | 256 | 256 | |
G-protein coupled receptor | 221 | 221 | |
actin family cytoskeletal prot... | 221 | 221 | |
KRAB box transcription factor | 193 | 193 | |
microtubule family cytoskeleta... | 189 | 189 | |
ion channel | 186 | 186 | |
G-protein modulator | 179 | 179 | |
dehydrogenase | 173 | 173 | |
phosphatase | 163 | 163 | |
G-protein | 131 | 131 | |
cation transporter | 127 | 127 | |
glycosyltransferase | 121 | 121 | |
nuclease | 110 | 110 | |
growth factor | 104 | 104 | |
cytokine | 101 | 101 | |
kinase modulator | 99 | 99 | |
ubiquitin-protein ligase | 99 | 99 | |
helix-turn-helix transcription... | 98 | 98 | |
transcription cofactor | 96 | 96 | |
serine protease | 79 | 79 | |
immunoglobulin | 76 | 76 | |
helicase | 75 | 75 | |
membrane trafficking regulator... | 75 | 75 | |
zinc finger transcription fact... | 74 | 74 | |
immunoglobulin receptor superf... | 71 | 71 | |
winged helix/forkhead transcri... | 70 | 70 | |
cysteine protease | 69 | 69 | |
acetyltransferase | 68 | 68 | |
oxygenase | 68 | 68 | |
basic helix-loop-helix transcr... | 60 | 60 | |
acyltransferase | 59 | 59 | |
extracellular matrix glycoprot... | 53 | 53 | |
methyltransferase | 53 | 53 | |
peptide hormone | 52 | 52 | |
phosphatase modulator | 51 | 51 | |
intracellular calcium-sensing ... | 47 | 47 | |
membrane-bound signaling molec... | 47 | 47 | |
reductase | 42 | 42 | |
C4 zinc finger nuclear recepto... | 41 | 41 | |
vesicle coat protein | 40 | 40 | |
ATP-binding cassette (ABC) tra... | 36 | 36 | |
cytokine receptor | 36 | 36 | |
tight junction | 35 | 35 | |
esterase | 32 | 32 | |
extracellular matrix structura... | 31 | 31 | |
SNARE protein | 30 | 30 | |
lipase | 30 | 30 | |
amino acid transporter | 28 | 28 | |
basic leucine zipper transcrip... | 27 | 27 | |
Rel homology transcription fac... | 25 | 25 | |
aminoacyl-tRNA synthetase | 24 | 24 | |
peroxidase | 24 | 24 | |
dehydratase | 23 | 23 | |
deaminase | 22 | 22 | |
gap junction | 21 | 21 | |
major histocompatibility compl... | 21 | 21 | |
carbohydrate transporter | 20 | 20 | |
nucleotidyltransferase | 20 | 20 | |
transaminase | 18 | 18 | |
glycosidase | 16 | 16 | |
metalloprotease | 16 | 16 | |
homeodomain transcription fact... | 15 | 15 | |
intermediate filament | 15 | 15 | |
mitochondrial carrier protein | 15 | 15 | |
HMG box transcription factor | 14 | 14 | |
apolipoprotein | 13 | 13 | |
chaperonin | 13 | 13 | |
annexin | 12 | 12 | |
decarboxylase | 12 | 12 | |
Hsp90 family chaperone | 9 | 9 | |
phosphorylase | 9 | 9 | |
glucosidase | 8 | 8 | |
cadherin | 7 | 7 | |
cyclase | 7 | 7 | |
antibacterial response protein | 6 | 6 | |
deacetylase | 6 | 6 | |
phosphodiesterase | 6 | 6 | |
MADS box transcription factor | 5 | 5 | |
galactosidase | 5 | 5 | |
hydroxylase | 5 | 5 | |
mutase | 5 | 5 | |
immunoglobulin superfamily cel... | 4 | 4 | |
pyrophosphatase | 4 | 4 | |
P53-like transcription factor | 3 | 3 | |
Runt transcription factor | 3 | 3 | |
TATA-binding transcription fac... | 3 | 3 | |
myelin protein | 3 | 3 | |
amylase | 2 | 2 | |
epimerase/racemase | 2 | 2 | |
protein kinase receptor | 2 | 2 | |
aldolase | 1 | 1 |
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