Development Level

Tbio 19 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased granulocyte number 1 | 6
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased erythrocyte cell num... 1 | 39
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 14 | 7,950
Carcinoma 12 | 11,493
lung cancer 10 | 4,740
ovarian cancer 9 | 8,520
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
psoriasis 8 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
Astrocytoma, Pilocytic 5 | 3,081
Systemic lupus erythematosus 5 | 194
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
medulloblastoma, large-cell 5 | 6,241
Atopic dermatitis 4 | 952
Breast cancer 4 | 3,578
Influenza 4 | 142
Influenza, Human 4 | 51
Microphthalmia with limb anomalies 4 | 40
Multiple Sclerosis 4 | 540
West Nile encephalitis 4 | 9
astrocytic glioma 4 | 2,597
cutaneous lupus erythematosus 4 | 1,057
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Autosomal recessive predisposition 3 | 1,442
Perlman syndrome 3 | 9
Pick disease 3 | 1,894
Retinitis pigmentosa 23 3 | 27
Type 2 diabetes mellitus 3 | 272
breast carcinoma 3 | 1,638
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primary Sjogren syndrome 3 | 735
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
COPD 2 | 118
Down syndrome 2 | 499
Hypermethioninemia 2 | 11
Kidney cancer 2 | 2,613
Optic Atrophy 2 | 242
Sleeping sickness 2 | 37
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
progressive supranuclear palsy 2 | 676
substance-related disorder 2 | 162
tick-borne encephalitis 2 | 14
Abnormal urinary amino-acid findings 1 | 38
Age related macular degeneration 1 | 72
Agoraphobia 1 | 21
Aminoaciduria 1 | 38
Babinski Reflex 1 | 100
Barrett's esophagus 1 | 182
Bleeding tendency 1 | 37
Blindness 1 | 88
Brain Diseases 1 | 24
Cardiovascular system disease 1 | 246
Cataract 4 multiple types 1 | 14
Cataract 7 1 | 32
Central nervous system demyelination 1 | 28
Decreased liver function 1 | 24
Eczema herpeticum 1 | 7
Fatty Liver 1 | 70
Fundus dystrophy 1 | 83
Hepatitis C 1 | 94
Homocystinuria 1 | 21
Icterus 1 | 82
Leber congenital amaurosis 1 | 69
Liver Failure 1 | 73
Liver dysfunction, mild 1 | 24
Macular degeneration 1 | 65
Metabolic acidosis 1 | 90
Nausea and vomiting 1 | 97
Neutropenia 1 | 72
Osteoporosis 1 | 363
Ovarian dysfunction 1 | 18
Pancreatitis 1 | 123
Peripheral demyelination 1 | 16
Precancerous Conditions 1 | 80
Premature Menopause 1 | 31
Premature ovarian failure 1 | 65
Primary hypogonadism 1 | 37
Toxic shock syndrome 1 | 28
Weight decreased 1 | 103
inflammatory breast cancer 1 | 286
post-traumatic stress disorder 1 | 40

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 20 | 4,145

PANTHER Protein Class (1)

nucleotidyltransferase 20 | 20
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Terminal uridylyltransferase 4 ZCCHC11 Tbio Enzyme -1.18900 14.5 147
DNA-directed RNA polymerase III subunit RPC8 POLR3H Tbio Enzyme -1.32118 21.0 104
Poly(A) RNA polymerase, mitochondrial MTPAP Tbio Enzyme -1.36829 24.0 68
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.54038 36.0 111
N-acylneuraminate cytidylyltransferase CMAS Tbio Enzyme -3.22957 1646.9 83
Speckle targeted PIP5K1A-regulated poly(A) polymerase TUT1 Tbio Enzyme -1.66339 47.9 64
2'-5'-oligoadenylate synthase 1 OAS1 Tbio Enzyme -2.01318 92.3 238
tRNA dimethylallyltransferase TRIT1 Tbio Enzyme -2.36135 237.3 69
Terminal uridylyltransferase 7 ZCCHC6 Tbio Enzyme -1.19915 15.1 23