Development Level

Tbio 107 | 10,625
Tdark 40 | 7,003
Tchem 5 | 1,890

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 6 | 148
preweaning lethality, incomple... 6 | 260
embryonic lethality prior to t... 3 | 187
prenatal lethality prior to he... 3 | 64
abnormal behavior 2 | 226
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
decreased CD4-positive, CD25-p... 2 | 24
decreased circulating glucose ... 2 | 121
decreased lumbar vertebrae num... 2 | 62
enlarged heart 2 | 111
increased bone mineral density 2 | 52
increased or absent threshold ... 2 | 128
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal neural tube morpholog... 1 | 8
abnormal ovary morphology 1 | 3
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
absent epididymis 1 | 2
absent teeth 1 | 4
aorta dilation 1 | 3
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart left ventricle... 1 | 2
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
shortened RR interval 1 | 19

Disease

osteosarcoma 77 | 7,933
ovarian cancer 70 | 8,484
psoriasis 51 | 6,685
medulloblastoma, large-cell 43 | 6,234
glioblastoma 39 | 5,572
lung cancer 31 | 4,466
atypical teratoid / rhabdoid tumor 30 | 4,369
oligodendroglioma 30 | 2,849
group 3 medulloblastoma 26 | 2,254
astrocytic glioma 24 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
malignant mesothelioma 22 | 3,162
pilocytic astrocytoma 22 | 3,086
primitive neuroectodermal tumor 22 | 3,031
Breast cancer 21 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
invasive ductal carcinoma 20 | 2,950
pediatric high grade glioma 20 | 2,712
Pick disease 17 | 1,893
group 4 medulloblastoma 17 | 1,875
pancreatic cancer 17 | 2,300
pituitary cancer 17 | 1,972
ependymoma 16 | 2,514
sonic hedgehog group medulloblastoma 16 | 1,482
Multiple myeloma 14 | 1,327
posterior fossa group A ependymoma 14 | 1,511
subependymal giant cell astrocytoma 14 | 2,287
Cancer 13 | 2,346
Carcinoma 13 | 2,147
astrocytoma 13 | 1,493
dermatomyositis 13 | 933
interstitial cystitis 13 | 2,299
non-small cell lung cancer 13 | 2,798
colon cancer 12 | 1,475
ductal carcinoma in situ 12 | 1,745
juvenile dermatomyositis 12 | 1,189
lung adenocarcinoma 12 | 2,713
lung carcinoma 12 | 2,844
Rheumatoid Arthritis 11 | 1,160
acute myeloid leukemia 11 | 780
adrenocortical carcinoma 11 | 1,427
adult high grade glioma 11 | 2,148
breast carcinoma 11 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
tuberculosis 10 | 1,557
ulcerative colitis 10 | 2,087
Waldenstrons macroglobulinemia 9 | 765
atypical teratoid/rhabdoid tumor 9 | 1,095
diabetes mellitus 9 | 1,663
cutaneous lupus erythematosus 8 | 1,056
acute quadriplegic myopathy 7 | 1,157
non primary Sjogren syndrome sicca 7 | 840
Amyotrophic Lateral Sclerosis 6 | 431
pancreatic carcinoma 6 | 567
posterior fossa group B ependymoma 6 | 1,530
Alzheimer's disease 5 | 644
Multiple Sclerosis 5 | 498
cystic fibrosis 5 | 1,665
hepatocellular carcinoma 5 | 532
primary Sjogren syndrome 5 | 789
primary pancreatic ductal adenocarcinoma 5 | 1,271
progressive supranuclear palsy 5 | 674
Atopic dermatitis 4 | 944
Endometriosis 4 | 535
Male infertility 4 | 170
Melanoma 4 | 261
Neurodegenerative disease 4 | 383
Obesity 4 | 616
Systemic scleroderma 4 | 66
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 557
nasopharyngeal carcinoma 4 | 1,056
spina bifida 4 | 1,064
tuberculosis and treatment for 6 months 4 | 686
Allergic hypersensitivity disease 3 | 123
Allergic rhinitis 3 | 91
Anemia 3 | 252
Asthma 3 | 349
Atrial heart septal defect 3 | 15
Attention deficit hyperactivity disorder 3 | 156
Brachydactyly 3 | 52
Colorectal Cancer 3 | 47
Colorectal Neoplasms 3 | 217
Congenital heart disease 3 | 63
Craniofacial Abnormalities 3 | 147
Down syndrome 3 | 548
Eosinophilia 3 | 65
Infertility 3 | 163
Pancreatic agenesis 3 | 14
Peripheral Neuropathy 3 | 303
Pontocerebellar hypoplasia 3 | 29
Schizophrenia 3 | 501
Tetralogy of Fallot 3 | 35
Type 2 diabetes mellitus 3 | 189
X-linked cerebral adrenoleukodystrophy 3 | 115
aldosterone-producing adenoma 3 | 664
chronic rhinosinusitis 3 | 512
gastric cancer 3 | 430
gastric carcinoma 3 | 832

Tissue

Endocrine System 150 | 18,512
Nervous System 149 | 18,561
Urinary Tract 149 | 18,444
Digestive Tract 147 | 18,473
Female tissues 147 | 18,647
Liver and Pancreas 147 | 18,136
Cardiovascular System 145 | 17,958
Male tissues 145 | 17,969
Skin and soft tissues 145 | 18,115
Blood and immune system 144 | 17,995
Respiratory system 137 | 17,484

Target Family

Non-IDG 62 | 11,971
Enzyme 54 | 4,146
Transcription Factor 28 | 1,400
Epigenetic 8 | 242

PANTHER Protein Class (1)

nuclease 152 | 152
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Class A basic helix-loop-helix protein 15 BHLHA15 Tbio Transcription Factor -1.24086 19.1 70
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
Oligodendrocyte transcription factor 3 OLIG3 Tbio Transcription Factor -0.81946 6.73 131
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675
Probable inactive ribonuclease-like protein 12 RNASE12 Tdark Enzyme 0.60 0.14 53
Inactive ribonuclease-like protein 10 RNASE10 Tdark Enzyme -0.65321 4.33 16
Probable inactive ribonuclease-like protein 13 RNASE13 Tbio Enzyme -1.12633 13.5 54
U3 small nucleolar RNA-associated protein 14 homolog A UTP14A Tdark Non-IDG -0.37115 2.10 96
Class E basic helix-loop-helix protein 23 BHLHE23 Tdark Transcription Factor -0.88352 7.52 11