Development Level

Tbio 87 | 11,651
Tdark 22 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 5 | 278
prenatal lethality prior to he... 5 | 87
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
decreased threshold for audito... 2 | 26
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
abnormal chorioallantoic fusio... 1 | 8
abnormal clavicle morphology 1 | 6
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal neural tube morpholog... 1 | 12
abnormal ovary morphology 1 | 7
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
absent epididymis 1 | 3
absent teeth 1 | 3
aorta dilation 1 | 3
cataract 1 | 92
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased urine magnesium leve... 1 | 3
embryonic growth retardation 1 | 106
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
shortened RR interval 1 | 17
thin ventricular wall 1 | 24

Disease

Carcinoma 61 | 11,493
osteosarcoma 55 | 7,950
ovarian cancer 50 | 8,520
psoriasis 37 | 6,694
medulloblastoma, large-cell 29 | 6,241
group 3 medulloblastoma 28 | 4,104
atypical teratoid / rhabdoid tumor 25 | 5,112
glioblastoma 24 | 5,792
lung cancer 24 | 4,740
oligodendroglioma 23 | 2,850
ependymoma 21 | 4,679
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
malignant mesothelioma 18 | 3,232
Kidney cancer 17 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
primitive neuroectodermal tumor 15 | 3,035
adult high grade glioma 14 | 3,801
pituitary cancer 14 | 1,972
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
pancreatic cancer 12 | 2,398
subependymal giant cell astrocytoma 12 | 2,287
Cancer 11 | 2,499
Multiple myeloma 11 | 1,332
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
astrocytoma 10 | 1,146
dermatomyositis 10 | 966
group 4 medulloblastoma 10 | 1,855
Pick disease 9 | 1,894
adrenocortical carcinoma 9 | 1,428
juvenile dermatomyositis 9 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
tuberculosis 9 | 2,010
acute myeloid leukemia 8 | 783
lung adenocarcinoma 8 | 2,716
Autosomal recessive predisposition 7 | 1,442
Waldenstrons macroglobulinemia 7 | 765
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
colon cancer 6 | 1,478
diabetes mellitus 6 | 1,728
pediatric high grade glioma 6 | 1,064
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Failure to gain weight 5 | 365
Intellectual disability 5 | 1,016
Male infertility 5 | 206
Melanoma 5 | 711
Pediatric failure to thrive 5 | 365
Schizophrenia 5 | 1,160
lung carcinoma 5 | 2,843
Brachydactyly 4 | 156
Cerebral atrophy 4 | 178
Dull intelligence 4 | 645
Feeding difficulties 4 | 127
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Short stature 4 | 531
Thrombocytopenia 4 | 197
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 891
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Anemia 3 | 365
Bilateral fifth finger clinodactyly 3 | 110
Colorectal Neoplasms 3 | 243
Congenital Epicanthus 3 | 177
Congenital heart disease 3 | 93
Curvature of little finger 3 | 110
Decreased platelet count 3 | 111
Endometriosis 3 | 540
Epilepsy 3 | 792
Infertility 3 | 188
Infertility, Male 3 | 46
Intrauterine retardation 3 | 176
Liver cancer 3 | 604
Muscle Spasticity 3 | 195
Neurodegenerative disease 3 | 414
Neutrophil count decreased 3 | 47
Pancytopenia 3 | 45
Pontocerebellar hypoplasia 3 | 36
Ventricular Septal Defects 3 | 119
X-linked cerebral adrenoleukodystrophy 3 | 116
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
hepatocellular carcinoma 3 | 547
pancreatic carcinoma 3 | 562

Tissue

Digestive Tract 102 | 17,369
Endocrine System 102 | 18,159
Nervous System 99 | 16,725
Female tissues 98 | 17,400
Liver and Pancreas 97 | 16,750
Male tissues 96 | 17,142
Skin and soft tissues 96 | 17,230
Respiratory system 95 | 16,393
Urinary Tract 95 | 16,678
Blood and immune system 94 | 16,909
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 46 | 12,091
Enzyme 30 | 4,145
Transcription Factor 25 | 1,400
Epigenetic 9 | 242

PANTHER Protein Class (1)

nuclease 110 | 110
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Nocturnin NOCT Tbio Non-IDG -1.84562 69.3 92
Ribonuclease P protein subunit p25 RPP25 Tbio Enzyme -1.05396 10.6 62
Cilia- and flagella-associated protein 20 CFAP20 Tbio Non-IDG -1.78803 43.9 88
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 PAN2 Tbio Enzyme -0.66901 4.14 87
U3 small nucleolar RNA-associated protein 14 homolog C UTP14C Tdark Non-IDG -0.60025 4.82 16
U3 small nucleolar RNA-associated protein 14 homolog A UTP14A Tdark Non-IDG -0.59151 4.35 107
CCR4-NOT transcription complex subunit 6 CNOT6 Tbio Non-IDG -1.27015 19.4 125
Density-regulated protein DENR Tbio Non-IDG -2.11857 120.3 133
DNA fragmentation factor subunit beta DFFB Tbio Non-IDG -1.82600 60.8 383