Development Level

Tbio 42 | 10,625
Tdark 16 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
decreased body weight 2 | 174
decreased circulating alanine ... 2 | 53
decreased circulating chloride... 2 | 32
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
abnormal allantois morphology 1 | 3
abnormal cranium morphology 1 | 32
abnormal heart morphology 1 | 51
abnormal incisor morphology 1 | 3
abnormal joint morphology 1 | 14
abnormal limb bud morphology 1 | 15
abnormal mandible morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
absent pinna reflex 1 | 21
decreased NK T cell number 1 | 28
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased follicular B cell nu... 1 | 4
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
improved glucose tolerance 1 | 56
increased KLRG1-positive NK ce... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased marginal zone B cell... 1 | 3
increased mean corpuscular hem... 1 | 93
increased monocyte cell number 1 | 27
increased red blood cell distr... 1 | 21
persistence of hyaloid vascula... 1 | 22

Disease

medulloblastoma, large-cell 24 | 6,234
osteosarcoma 23 | 7,933
ovarian cancer 22 | 8,492
glioblastoma 20 | 5,572
atypical teratoid / rhabdoid tumor 19 | 4,369
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
primitive neuroectodermal tumor 13 | 3,031
psoriasis 13 | 6,685
Breast cancer 12 | 3,099
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
lung cancer 12 | 4,473
medulloblastoma 12 | 1,524
ependymoma 11 | 2,514
astrocytic glioma 10 | 2,241
pilocytic astrocytoma 10 | 3,086
adult high grade glioma 9 | 2,148
pediatric high grade glioma 9 | 2,712
Pick disease 8 | 1,893
Rheumatoid Arthritis 7 | 1,171
lung carcinoma 7 | 2,844
malignant mesothelioma 7 | 3,163
Multiple myeloma 6 | 1,328
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
oligodendroglioma 6 | 2,849
subependymal giant cell astrocytoma 6 | 2,287
Duchenne muscular dystrophy 5 | 602
Obesity 5 | 616
acute quadriplegic myopathy 5 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,714
non-small cell lung cancer 5 | 2,798
posterior fossa group A ependymoma 5 | 1,511
ulcerative colitis 5 | 2,087
astrocytoma 4 | 1,493
group 4 medulloblastoma 4 | 1,875
juvenile dermatomyositis 4 | 1,189
non primary Sjogren syndrome sicca 4 | 840
posterior fossa group B ependymoma 4 | 1,530
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,563
Deafness dystonia syndrome 3 | 20
IGA Glomerulonephritis 3 | 454
Metabolic syndrome X 3 | 155
Ornithine translocase deficiency 3 | 5
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 785
atypical teratoid/rhabdoid tumor 3 | 1,095
cystic fibrosis 3 | 1,670
dermatomyositis 3 | 967
ductal carcinoma in situ 3 | 1,745
limb girdle muscular dystrophy 2A 3 | 156
pancreatic cancer 3 | 2,300
Anemia 2 | 252
Animal Mammary Neoplasms 2 | 136
Argininosuccinic aciduria 2 | 17
Asperger syndrome 2 | 35
Barth syndrome 2 | 23
Becker muscular dystrophy 2 | 187
Cardiomyopathy 2 | 110
Citrullinemia 2 | 13
Dystonia 2 | 77
Hyperglycemia 2 | 120
Intrahepatic cholestasis 2 | 19
Mammary Neoplasms, Experimental 2 | 150
Multiple Sclerosis 2 | 498
Multiple carboxylase deficiency 2 | 7
Neuropathy 2 | 210
Systemic primary carnitine deficiency disease 2 | 16
Urea cycle disorder 2 | 7
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 550
hereditary spastic paraplegia 2 | 313
non-inflammatory breast cancer 2 | 208
pituitary cancer 2 | 1,972
Adult-onset citrullinemia type 2 1 | 1
Bilirubin metabolic disorder 1 | 39
CITRULLINEMIA, TYPE II, NEONATAL-ONSET 1 | 1
Cardiomegaly 1 | 66
Carnitine palmitoyltransferase II deficiency 1 | 16
Cholestasis, neonatal intrahepatic, caused by citrin deficiency 1 | 1
Citrullinemia 2 1 | 1
Congenital nystagmus 1 | 26
DiGeorge syndrome 1 | 46
Diabetes Mellitus, Experimental 1 | 106
Fatty Liver 1 | 48
Fatty liver disease 1 | 86
Galactosemia 1 | 20
Hepatic encephalopathy 1 | 25
Hyperargininemia 1 | 7
Mucoepidermoid carcinoma 1 | 19
Paget's disease of bone 1 | 28
Phenylketonuria 1 | 18
Rhabdomyosarcoma 1 | 29
Strongyloidiasis 1 | 9
Velocardiofacial syndrome 1 | 45

Tissue

Blood and immune system 58 | 17,995
Male tissues 58 | 17,969
Cardiovascular System 57 | 17,958
Digestive Tract 57 | 18,473
Endocrine System 57 | 18,512
Female tissues 57 | 18,647
Liver and Pancreas 57 | 18,136
Nervous System 57 | 18,561
Respiratory system 57 | 17,484
Skin and soft tissues 57 | 18,115
Urinary Tract 57 | 18,444

Target Family

Transporter 47 | 473
Non-IDG 6 | 11,969
Enzyme 5 | 4,146

PANTHER Protein Class (1)

mitochondrial carrier protein 58 | 58
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial coenzyme A transporter SLC25A42 SLC25A42 Tbio Transporter -0.38872 3.06 24
Solute carrier family 25 member 33 SLC25A33 Tbio Transporter -0.28165 1.49 35
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.72649 574.1 155
Solute carrier family 25 member 43 SLC25A43 Tdark Transporter -0.36486 3.44 8
S-adenosylmethionine mitochondrial carrier protein SLC25A26 Tbio Transporter -1.45628 32.7 25
28S ribosomal protein S17, mitochondrial MRPS17 Tbio Non-IDG 0.44 0.00000 22
Mitochondrial thiamine pyrophosphate carrier SLC25A19 Tbio Transporter -2.30703 181.5 60
Mitochondrial uncoupling protein 4 SLC25A27 Tbio Transporter -1.53756 39.6 45
Mitochondrial import inner membrane translocase subunit TIM44 TIMM44 Tdark Enzyme -1.52890 44.0 29
Mitochondrial ornithine transporter 2 SLC25A2 Tbio Transporter -0.47105 2.47 81