Development Level

Tbio 113 | 10,625
Tdark 67 | 7,003
Tchem 22 | 1,890
Tclin 9 | 602

IMPC Term

preweaning lethality, complete... 14 | 633
hyperactivity 4 | 108
abnormal behavior 3 | 226
abnormal embryo size 3 | 112
decreased circulating glucose ... 3 | 121
increased hematocrit 3 | 36
increased lean body mass 3 | 107
preweaning lethality, incomple... 3 | 260
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
decreased bone mineral content 2 | 157
decreased circulating serum al... 2 | 79
decreased lean body mass 2 | 195
impaired glucose tolerance 2 | 52
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased fasted circulating g... 2 | 68
increased or absent threshold ... 2 | 128
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal limb morphology 1 | 7
abnormal outer ear morphology 1 | 1
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
absent pinna reflex 1 | 21
cataract 1 | 26
convulsive seizures 1 | 11
cyanosis 1 | 6
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased effector memory CD4-... 1 | 6
decreased eosinophil cell numb... 1 | 41
decreased hematocrit 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased red blood cell distr... 1 | 11
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hemorrhage 1 | 12
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
protruding tongue 1 | 1

Disease

ovarian cancer 97 | 8,484
osteosarcoma 85 | 7,933
medulloblastoma, large-cell 80 | 6,234
psoriasis 71 | 6,685
glioblastoma 69 | 5,572
lung cancer 60 | 4,466
atypical teratoid / rhabdoid tumor 56 | 4,369
posterior fossa group B ependymoma 46 | 1,530
malignant mesothelioma 45 | 3,162
Breast cancer 44 | 3,094
non-small cell lung cancer 44 | 2,798
primitive neuroectodermal tumor 44 | 3,031
pediatric high grade glioma 42 | 2,712
Carcinoma 38 | 2,147
invasive ductal carcinoma 38 | 2,950
pilocytic astrocytoma 38 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,988
oligodendroglioma 37 | 2,849
nasopharyngeal carcinoma 35 | 1,056
group 3 medulloblastoma 34 | 2,254
lung carcinoma 33 | 2,844
colon cancer 30 | 1,475
ependymoma 30 | 2,514
lung adenocarcinoma 30 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
breast carcinoma 28 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,956
Pick disease 27 | 1,893
subependymal giant cell astrocytoma 26 | 2,287
pancreatic cancer 25 | 2,300
ductal carcinoma in situ 23 | 1,745
astrocytic glioma 22 | 2,241
sonic hedgehog group medulloblastoma 21 | 1,482
adrenocortical carcinoma 20 | 1,427
adult high grade glioma 20 | 2,148
chronic rhinosinusitis 20 | 512
pituitary cancer 20 | 1,972
Atopic dermatitis 18 | 944
group 4 medulloblastoma 18 | 1,875
posterior fossa group A ependymoma 18 | 1,511
Primary ciliary dyskinesia 17 | 73
atypical teratoid/rhabdoid tumor 17 | 1,095
ulcerative colitis 17 | 2,087
astrocytoma 16 | 1,493
interstitial cystitis 16 | 2,299
Cancer 15 | 2,346
Endometriosis 14 | 535
juvenile dermatomyositis 14 | 1,189
Neurodegenerative disease 13 | 383
dermatomyositis 13 | 933
Microcephaly 12 | 149
Multiple myeloma 12 | 1,327
Situs Inversus 12 | 48
diabetes mellitus 12 | 1,663
primary pancreatic ductal adenocarcinoma 12 | 1,271
progressive supranuclear palsy 12 | 674
cutaneous lupus erythematosus 11 | 1,056
cystic fibrosis 11 | 1,665
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
IGA Glomerulonephritis 10 | 454
Kaposi's sarcoma 10 | 20
Lissencephaly 10 | 61
Neuroblastoma 10 | 78
fibroadenoma 10 | 557
spina bifida 10 | 1,064
tuberculosis 10 | 1,557
Acute lymphoid leukemia 9 | 25
Amyotrophic Lateral Sclerosis 9 | 431
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 10
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 58
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of prostate 9 | 11
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Mycosis fungoides 9 | 28
Nephroblastoma 9 | 45
Neuropathy 9 | 210
Non-Hodgkin's lymphoma 9 | 22
Ocular hypertension 9 | 27
Open-angle glaucoma 9 | 26
Rhabdomyosarcoma 9 | 29
Secondary malignant neoplasm of pancreas 9 | 10
Transitional cell carcinoma 9 | 18
acute quadriplegic myopathy 9 | 1,157
medulloblastoma 9 | 1,524
gastric cancer 8 | 430
hepatocellular carcinoma 8 | 532

Tissue

Blood and immune system 200 | 17,995
Endocrine System 199 | 18,512
Female tissues 199 | 18,647
Male tissues 199 | 17,969
Nervous System 199 | 18,561
Cardiovascular System 198 | 17,958
Digestive Tract 198 | 18,473
Liver and Pancreas 198 | 18,136
Urinary Tract 198 | 18,444
Skin and soft tissues 197 | 18,115
Respiratory system 196 | 17,484

Target Family

Non-IDG 190 | 11,971
Enzyme 21 | 4,146

PANTHER Protein Class (1)

microtubule family cytoskeleta... 211 | 211
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Microtubule-associated protein RP/EB family member 3 MAPRE3 Tbio Non-IDG -2.14681 132.5 161
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.32941 210.3 40
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
WD repeat-containing protein 63 WDR63 Tdark Non-IDG -0.73038 5.69 23
Kinesin-like protein KIFC3 KIFC3 Tchem Non-IDG -1.08696 12.5 48
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.16914 1.36 38
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84