Development Level

Tbio 111 | 11,178
Tdark 47 | 6,569
Tchem 22 | 1,885
Tclin 9 | 612

IMPC Phenotype

preweaning lethality, complete... 20 | 979
preweaning lethality, incomple... 7 | 499
abnormal embryo size 5 | 220
hyperactivity 4 | 148
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
cataract 2 | 92
cyanosis 2 | 7
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
impaired glucose tolerance 2 | 75
increased circulating chloride... 2 | 41
increased hematocrit 2 | 46
long tibia 2 | 25
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
abnormal vitreous body morphol... 1 | 10
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating lactate ... 1 | 3
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged testis 1 | 6
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
protruding tongue 1 | 3
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 137 | 11,192
ovarian cancer 88 | 8,297
ependymoma 74 | 4,559
medulloblastoma, large-cell 74 | 6,086
osteosarcoma 73 | 7,766
atypical teratoid / rhabdoid tumor 65 | 4,971
psoriasis 65 | 6,514
glioblastoma 63 | 5,635
lung cancer 58 | 4,607
Breast cancer 54 | 3,469
group 3 medulloblastoma 52 | 4,002
adult high grade glioma 50 | 3,701
Kidney cancer 44 | 2,548
malignant mesothelioma 44 | 3,135
primitive neuroectodermal tumor 43 | 2,957
non-small cell lung cancer 41 | 2,799
Astrocytoma, Pilocytic 36 | 3,006
nasopharyngeal carcinoma 35 | 1,024
invasive ductal carcinoma 34 | 2,867
oligodendroglioma 34 | 2,768
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,902
colon cancer 30 | 1,428
lung carcinoma 30 | 2,755
lung adenocarcinoma 29 | 2,627
pancreatic cancer 28 | 2,322
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,204
Pick disease 26 | 1,856
breast carcinoma 26 | 1,589
subependymal giant cell astrocytoma 26 | 2,230
astrocytic glioma 23 | 2,530
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,872
ductal carcinoma in situ 22 | 1,686
Liver cancer 20 | 589
adrenocortical carcinoma 20 | 1,385
chronic rhinosinusitis 20 | 505
Atopic dermatitis 18 | 915
Primary ciliary dyskinesia 18 | 75
pituitary cancer 18 | 1,915
interstitial cystitis 16 | 2,237
ulcerative colitis 15 | 1,765
Autosomal recessive predisposition 14 | 1,407
Cancer 14 | 2,388
Endometriosis 14 | 521
Microcephaly 14 | 166
Small head 14 | 366
group 4 medulloblastoma 14 | 1,806
juvenile dermatomyositis 14 | 1,147
Endometrial cancer 13 | 301
Intellectual disability 13 | 998
Epilepsy 12 | 775
Neurodegenerative disease 12 | 402
dermatomyositis 12 | 941
Melanoma 11 | 689
Multiple myeloma 11 | 1,296
Seizures 11 | 584
Situs Inversus 11 | 61
cystic fibrosis 11 | 1,629
primary pancreatic ductal adenocarcinoma 11 | 1,071
progressive supranuclear palsy 11 | 656
Kaposi's sarcoma 10 | 22
Muscle hypotonia 10 | 562
Neuroblastoma 10 | 79
cutaneous lupus erythematosus 10 | 1,016
diabetes mellitus 10 | 1,683
tuberculosis 10 | 1,963
Acute lymphoid leukemia 9 | 25
Amyotrophic lateral sclerosis 9 | 437
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Cognitive delay 9 | 596
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
Global developmental delay 9 | 596
HER2-positive carcinoma of breast 9 | 21
Hodgkin's disease 9 | 18
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Lissencephaly 9 | 69
Male infertility 9 | 199
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Mental and motor retardation 9 | 596
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Nephroblastoma 9 | 50
Neuropathy 9 | 254
Non-Hodgkin's lymphoma 9 | 22
Ocular hypertension 9 | 40
Open-angle glaucoma 9 | 27
Rhabdomyosarcoma 9 | 39
Secondary malignant neoplasm of pancreas 9 | 10
astrocytoma 9 | 1,113
fibroadenoma 9 | 538
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,911
posterior fossa group B ependymoma 9 | 406
spina bifida 9 | 1,053
transitional cell carcinoma 9 | 22

Tissue

Endocrine System 182 | 18,159
Female tissues 174 | 17,400
Skin and soft tissues 173 | 17,230
Male tissues 172 | 17,142
Respiratory system 171 | 16,393
Digestive Tract 170 | 17,369
Nervous System 170 | 16,725
Urinary Tract 169 | 16,678
Blood and immune system 167 | 16,909
Liver and Pancreas 167 | 16,750
Cardiovascular System 154 | 15,192

Target Family

Non-IDG 174 | 12,091
Enzyme 15 | 4,145

PANTHER Protein Class (1)

microtubule family cytoskeleta... 189 | 189
RNA binding protein 476 | 476
kinase 357 | 357
DNA binding protein 338 | 338
protease 224 | 224
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
protease inhibitor 196 | 196
KRAB box transcription factor 193 | 193
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
transcription cofactor 96 | 96
helix-turn-helix transcription... 87 | 87
ubiquitin-protein ligase 83 | 83
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
zinc finger transcription fact... 50 | 50
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
basic helix-loop-helix transcr... 42 | 42
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
nucleotidyltransferase 20 | 20
transaminase 18 | 18
metalloprotease 16 | 16
carbohydrate transporter 15 | 15
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
basic leucine zipper transcrip... 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
glycosidase 11 | 11
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
phosphodiesterase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
HMG box transcription factor 1 | 1
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210
Dynein heavy chain 5, axonemal DNAH5 Tbio Non-IDG -1.46000 27.2 32
Tubulin polyglutamylase TTLL13P TTLL13P Tdark Enzyme 0.78 0.17 0
Kinesin-like protein KIF17 KIF17 Tbio Non-IDG -2.01401 107.8 73
Tubulin beta-4B chain TUBB4B Tclin Non-IDG -0.95954 8.09 107
Kinesin heavy chain isoform 5C KIF5C Tbio Non-IDG -1.43450 25.5 119
Cytoskeleton-associated protein 5 CKAP5 Tbio Non-IDG -2.12618 129.3 77
Dynein heavy chain 2, axonemal DNAH2 Tdark Non-IDG -0.65482 4.13 58
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77
Dynein heavy chain 1, axonemal DNAH1 Tbio Non-IDG -1.30285 17.4 21