Development Level

Tbio 25 | 11,445
Tdark 14 | 6,588
Tchem 12 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
abnormal coat-hair pigmentatio... 2 | 64
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
male infertility 2 | 123
abnormal behavior 1 | 298
abnormal embryo turning 1 | 31
abnormal locomotor behavior 1 | 24
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
excessive tearing 1 | 2
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased startle reflex 1 | 112
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 28 | 8,520
Carcinoma 26 | 11,493
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 18 | 6,241
psoriasis 17 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
lung cancer 14 | 4,740
ependymoma 13 | 4,679
group 3 medulloblastoma 11 | 4,104
non-small cell lung cancer 11 | 2,890
Cancer 9 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
adult high grade glioma 8 | 3,801
Astrocytoma, Pilocytic 7 | 3,081
Schizophrenia 7 | 1,160
malignant mesothelioma 7 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
Breast cancer 6 | 3,578
Multiple myeloma 6 | 1,332
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
acute myeloid leukemia 5 | 783
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
progressive supranuclear palsy 5 | 676
Attention deficit hyperactivity disorder 4 | 278
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
Pick disease 4 | 1,894
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
Adenocarcinoma of lung 3 | 142
Adverse reaction to drug 3 | 61
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Drug-Related Side Effects and Adverse Reactions 3 | 62
Intellectual disability 3 | 1,016
Mental Depression 3 | 333
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409
Acquired metabolic disease 2 | 336
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Blepharoptosis 2 | 231
Blindness 2 | 88
Carcinoma, Hepatocellular 2 | 228
Cleft Palate 2 | 271
Cocaine-Related Disorders 2 | 92
Cognitive delay 2 | 608
Congenital Epicanthus 2 | 177
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Down syndrome 2 | 499
Endometriosis 2 | 540
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Hypertension 2 | 396
Kidney cancer 2 | 2,613
Liver carcinoma 2 | 240
Long face 2 | 71
Low set ears 2 | 181
Lymphoma, Non-Hodgkin 2 | 24
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Parkinson's disease 2 | 392
Prostatic Neoplasms 2 | 495
Short stature 2 | 531
Telecanthus 2 | 62
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
nervous system disorder 2 | 53
non diabetic and post-ischemic heart failure 2 | 200
non primary Sjogren syndrome sicca 2 | 891
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819

Tissue

Cardiovascular System 52 | 15,192
Endocrine System 52 | 18,159
Liver and Pancreas 52 | 16,750
Female tissues 51 | 17,400
Nervous System 51 | 16,725
Respiratory system 51 | 16,393
Skin and soft tissues 51 | 17,230
Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Male tissues 50 | 17,142
Urinary Tract 50 | 16,678

Target Family

Enzyme 42 | 4,145
Epigenetic 8 | 242
Non-IDG 3 | 12,091

PANTHER Protein Class (1)

methyltransferase 53 | 53
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Catechol O-methyltransferase COMT Tclin Enzyme -3.46304 2976.1 433
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Phenylethanolamine N-methyltransferase PNMT Tchem Enzyme -2.90323 857.6 277
Serine hydroxymethyltransferase, cytosolic SHMT1 Tbio Enzyme -2.58690 370.4 181
Methionyl-tRNA formyltransferase, mitochondrial MTFMT Tbio Enzyme -2.42792 264.8 69
Acetylserotonin O-methyltransferase ASMT Tbio Enzyme -2.40166 255.0 111
Serine hydroxymethyltransferase, mitochondrial SHMT2 Tbio Enzyme -2.39227 240.3 137
Protein arginine N-methyltransferase 1 PRMT1 Tchem Epigenetic -2.35804 229.5 394
Histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1L Tchem Epigenetic -2.29797 199.6 330