Development Level

Tbio 90 | 10,625
Tdark 25 | 7,003
Tchem 10 | 1,890

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased rib number 2 | 59
enlarged heart 2 | 111
enlarged kidney 2 | 7
female infertility 2 | 34
improved glucose tolerance 2 | 56
increased fasted circulating g... 2 | 68
increased mean corpuscular vol... 2 | 91
preweaning lethality, complete... 2 | 633
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal gait 1 | 51
abnormal nail morphology 1 | 7
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
absent vibrissae 1 | 14
cataract 1 | 26
corneal opacity 1 | 25
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged adrenal glands 1 | 3
enlarged spleen 1 | 26
enlarged uterus 1 | 3
hydrometra 1 | 13
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating alkaline... 1 | 119
increased circulating iron lev... 1 | 25
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
male infertility 1 | 62
mydriasis 1 | 9
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 58 | 6,685
ovarian cancer 56 | 8,484
osteosarcoma 48 | 7,933
glioblastoma 47 | 5,572
lung cancer 44 | 4,466
lung carcinoma 40 | 2,844
medulloblastoma, large-cell 39 | 6,234
pilocytic astrocytoma 39 | 3,086
invasive ductal carcinoma 35 | 2,950
malignant mesothelioma 33 | 3,162
atypical teratoid / rhabdoid tumor 31 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,988
non-small cell lung cancer 31 | 2,798
lung adenocarcinoma 30 | 2,713
interstitial cystitis 28 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
pediatric high grade glioma 26 | 2,712
Cancer 25 | 2,346
Breast cancer 23 | 3,094
ependymoma 23 | 2,514
oligodendroglioma 23 | 2,849
pancreatic cancer 23 | 2,300
adult high grade glioma 22 | 2,148
cutaneous lupus erythematosus 21 | 1,056
ulcerative colitis 21 | 2,087
cystic fibrosis 20 | 1,665
ductal carcinoma in situ 20 | 1,745
Carcinoma 19 | 2,147
astrocytic glioma 19 | 2,241
posterior fossa group A ependymoma 19 | 1,511
breast carcinoma 18 | 1,614
primitive neuroectodermal tumor 18 | 3,031
pituitary cancer 17 | 1,972
subependymal giant cell astrocytoma 17 | 2,287
tuberculosis 17 | 1,557
group 4 medulloblastoma 16 | 1,875
sonic hedgehog group medulloblastoma 15 | 1,482
group 3 medulloblastoma 14 | 2,254
colon cancer 13 | 1,475
primary pancreatic ductal adenocarcinoma 13 | 1,271
Pick disease 11 | 1,893
astrocytoma 11 | 1,493
esophageal adenocarcinoma 11 | 737
Atopic dermatitis 9 | 944
diabetes mellitus 9 | 1,663
non-small cell lung carcinoma 9 | 413
primary Sjogren syndrome 9 | 789
fibroadenoma 8 | 557
posterior fossa group B ependymoma 8 | 1,530
Down syndrome 7 | 548
Duchenne muscular dystrophy 7 | 602
Polycystic kidney disease 7 | 54
adrenocortical carcinoma 7 | 1,427
juvenile dermatomyositis 7 | 1,189
mucosa-associated lymphoid tissue lymphoma 7 | 480
nasopharyngeal carcinoma 7 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
spina bifida 7 | 1,064
Mammary Neoplasms 6 | 410
Obesity 6 | 616
atypical teratoid/rhabdoid tumor 6 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
inflammatory breast cancer 6 | 404
medulloblastoma 6 | 1,524
nephrosclerosis 6 | 329
Barrett's esophagus 5 | 183
Multiple myeloma 5 | 1,327
Retinitis pigmentosa 5 | 153
Rheumatoid Arthritis 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
aldosterone-producing adenoma 5 | 664
dermatomyositis 5 | 933
gastric carcinoma 5 | 832
non primary Sjogren syndrome sicca 5 | 840
progressive supranuclear palsy 5 | 674
urothelial carcinoma 5 | 318
Asthma 4 | 349
Cerebrovascular disease 4 | 231
Craniofrontonasal syndrome 4 | 13
Crohn's disease 4 | 304
Gaucher disease type 1 4 | 171
Hajdu-Cheney syndrome 4 | 8
Human immunodeficiency virus infectious disease 4 | 92
IGA Glomerulonephritis 4 | 454
Multiple Sclerosis 4 | 498
active ulcerative colitis 4 | 477
pancreatic carcinoma 4 | 567
tuberculosis and treatment for 6 months 4 | 686
Alzheimer's disease 3 | 644
Craniosynostosis 3 | 47
Endometriosis 3 | 535
Hypersensitivity reaction type II disease 3 | 235
Kidney disease 3 | 396
Migraine 3 | 79
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
chronic rhinosinusitis 3 | 512
glioblastoma multiforme 3 | 347
head and neck cancer 3 | 270

Tissue

Blood and immune system 125 | 17,995
Digestive Tract 125 | 18,473
Liver and Pancreas 124 | 18,136
Nervous System 124 | 18,561
Urinary Tract 124 | 18,444
Cardiovascular System 123 | 17,958
Endocrine System 123 | 18,512
Female tissues 123 | 18,647
Skin and soft tissues 123 | 18,115
Male tissues 121 | 17,969
Respiratory system 121 | 17,484

Target Family

Non-IDG 114 | 11,971
Ion Channel 7 | 341
Enzyme 3 | 4,146
Kinase 1 | 634

PANTHER Protein Class (1)

membrane-bound signaling molec... 125 | 125
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Killer cell lectin-like receptor subfamily B member 1 KLRB1 Tbio Non-IDG -2.39953 313.9 488
NKG2-C type II integral membrane protein KLRC2 Tbio Non-IDG -1.86834 75.2 128
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.48442 31.1 337
NKG2-A/NKG2-B type II integral membrane protein KLRC1 Tbio Non-IDG -2.40441 255.8 351
Tetraspanin-18 TSPAN18 Tbio Non-IDG -0.83372 7.78 40
Semaphorin-3E SEMA3E Tbio Non-IDG -1.51645 40.3 201
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739
Tetraspanin-11 TSPAN11 Tdark Non-IDG 0.26 0.18 15
Tetraspanin-14 TSPAN14 Tdark Non-IDG -0.11344 1.08 33
CD81 antigen CD81 Tchem Non-IDG -2.72554 534.7 551