Development Level

Tbio 42 | 11,651
Tdark 4 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
cataract 3 | 92
abnormal sleep behavior 2 | 70
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal nail morphology 1 | 8
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 51
decreased circulating glucose ... 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
enlarged adrenal glands 1 | 3
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
mydriasis 1 | 6
polycystic kidney 1 | 15

Disease

Carcinoma 34 | 11,493
psoriasis 28 | 6,694
lung cancer 25 | 4,740
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 20 | 6,241
invasive ductal carcinoma 19 | 2,951
glioblastoma 18 | 5,792
osteosarcoma 18 | 7,950
Breast cancer 17 | 3,578
lung carcinoma 17 | 2,843
atypical teratoid / rhabdoid tumor 16 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
lung adenocarcinoma 16 | 2,716
malignant mesothelioma 16 | 3,232
adult high grade glioma 15 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
pancreatic cancer 14 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
ependymoma 13 | 4,679
pituitary cancer 13 | 1,972
astrocytic glioma 12 | 2,597
cystic fibrosis 12 | 1,696
group 3 medulloblastoma 12 | 4,104
Kidney cancer 11 | 2,613
oligodendroglioma 11 | 2,850
Cancer 10 | 2,499
breast carcinoma 10 | 1,638
non-small cell lung cancer 10 | 2,890
primitive neuroectodermal tumor 10 | 3,035
cutaneous lupus erythematosus 9 | 1,057
interstitial cystitis 9 | 2,312
ulcerative colitis 9 | 1,819
ductal carcinoma in situ 8 | 1,745
subependymal giant cell astrocytoma 8 | 2,287
group 4 medulloblastoma 7 | 1,855
tuberculosis 7 | 2,010
Pick disease 6 | 1,894
colon cancer 6 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary pancreatic ductal adenocarcinoma 6 | 1,109
Melanoma 5 | 711
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
esophageal adenocarcinoma 5 | 737
non-small cell lung carcinoma 5 | 317
pediatric high grade glioma 5 | 1,064
posterior fossa group A ependymoma 5 | 468
Atopic dermatitis 4 | 952
Craniofrontonasal syndrome 4 | 13
Down syndrome 4 | 499
fibroadenoma 4 | 559
progressive supranuclear palsy 4 | 676
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Breast Neoplasms 3 | 445
Chronic obstructive pulmonary disease 3 | 184
Cryptorchidism 3 | 296
Downward slant of palpebral fissure 3 | 158
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Gaucher disease type 1 3 | 180
Kallmann syndrome 3 | 33
Mammary Neoplasms 3 | 425
Muscle hypotonia 3 | 571
Obesity 3 | 678
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Attention deficit hyperactivity disorder 2 | 278
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Craniosynostosis 2 | 74
Curvature of spine 2 | 282
Endometrial cancer 2 | 311
Glaucoma 2 | 239
Hypersensitivity reaction type II disease 2 | 253
Multiple Sclerosis 2 | 540
Nasal bridge wide 2 | 236
Reperfusion Injury 2 | 86
Umbilical hernia 2 | 93
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
head and neck cancer 2 | 271
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Nervous System 46 | 16,725
Male tissues 45 | 17,142
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Urinary Tract 45 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 45 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

PANTHER Protein Class (1)

membrane-bound signaling molec... 47 | 47
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Semaphorin-3C SEMA3C Tbio Non-IDG -1.95299 88.1 184
Semaphorin-3E SEMA3E Tbio Non-IDG -1.62878 48.9 219
Ephrin-B2 EFNB2 Tbio Non-IDG -2.45068 288.9 381
Semaphorin-4F SEMA4F Tbio Non-IDG -1.03391 11.3 95
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -2.05224 110.5 188
Melanocyte protein PMEL PMEL Tbio Non-IDG -2.80502 640.6 530
Ephrin-A5 EFNA5 Tbio Non-IDG -2.57120 355.6 202
Semaphorin-4A SEMA4A Tbio Non-IDG -1.66081 49.4 292
Semaphorin-6D SEMA6D Tbio Non-IDG -1.20050 15.1 129