Development Level

Tbio 82 | 10,625
Tdark 24 | 7,003

IMPC Phenotype

preweaning lethality, complete... 3 | 633
decreased circulating LDL chol... 2 | 37
increased hematocrit 2 | 36
abnormal thoracic cage shape 1 | 3
abnormal vertebrae morphology 1 | 14
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
increased body weight 1 | 42
increased circulating calcium ... 1 | 32
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

ovarian cancer 56 | 8,491
osteosarcoma 49 | 7,933
medulloblastoma, large-cell 45 | 6,234
glioblastoma 43 | 5,572
psoriasis 37 | 6,685
atypical teratoid / rhabdoid tumor 33 | 4,369
pilocytic astrocytoma 30 | 3,086
lung carcinoma 25 | 2,844
oligodendroglioma 25 | 2,849
pediatric high grade glioma 23 | 2,712
primitive neuroectodermal tumor 22 | 3,031
Pick disease 21 | 1,893
Breast cancer 20 | 3,098
lung cancer 20 | 4,473
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
invasive ductal carcinoma 19 | 2,950
subependymal giant cell astrocytoma 19 | 2,287
astrocytic glioma 18 | 2,241
ependymoma 18 | 2,514
pituitary cancer 17 | 1,972
group 3 medulloblastoma 16 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
non-small cell lung cancer 16 | 2,798
astrocytoma 15 | 1,493
interstitial cystitis 15 | 2,299
malignant mesothelioma 14 | 3,163
pancreatic cancer 13 | 2,300
adult high grade glioma 12 | 2,148
ductal carcinoma in situ 12 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
sonic hedgehog group medulloblastoma 12 | 1,482
posterior fossa group A ependymoma 11 | 1,511
diabetes mellitus 10 | 1,663
group 4 medulloblastoma 10 | 1,875
medulloblastoma 10 | 1,524
posterior fossa group B ependymoma 10 | 1,530
tuberculosis 10 | 1,563
dermatomyositis 9 | 966
Carcinoma 8 | 2,147
Multiple myeloma 8 | 1,327
Waldenstrons macroglobulinemia 8 | 764
acute quadriplegic myopathy 8 | 1,157
lung adenocarcinoma 8 | 2,714
primary pancreatic ductal adenocarcinoma 8 | 1,271
spina bifida 8 | 1,064
ulcerative colitis 8 | 2,087
Duchenne muscular dystrophy 7 | 602
active Crohn's disease 7 | 918
atypical teratoid/rhabdoid tumor 7 | 1,095
breast carcinoma 7 | 1,614
juvenile dermatomyositis 7 | 1,189
acute myeloid leukemia 6 | 785
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
cutaneous lupus erythematosus 6 | 1,056
Down syndrome 5 | 548
Neurodegenerative disease 5 | 383
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,670
nasopharyngeal carcinoma 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
tuberculosis and treatment for 6 months 5 | 686
Alzheimer's disease 4 | 644
Amyotrophic Lateral Sclerosis 4 | 432
Cancer 4 | 2,346
Rheumatoid Arthritis 4 | 1,170
Type 2 diabetes mellitus 4 | 192
active ulcerative colitis 4 | 477
adrenocortical carcinoma 4 | 1,427
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 557
gastric cancer 4 | 436
inflammatory breast cancer 4 | 404
pancreatic carcinoma 4 | 567
ARC syndrome 3 | 14
Acquired metabolic disease 3 | 267
Atopic dermatitis 3 | 944
Becker muscular dystrophy 3 | 187
Bipolar Disorder 3 | 266
Botulism 3 | 20
Diabetes Mellitus, Non-Insulin-Dependent 3 | 161
Epilepsy 3 | 346
IGA Glomerulonephritis 3 | 454
Intellectual disability 3 | 573
Parkinson's disease 3 | 364
Schizophrenia 3 | 503
aldosterone-producing adenoma 3 | 664
gastric carcinoma 3 | 832
head and neck cancer 3 | 270
primary Sjogren syndrome 3 | 788
progressive supranuclear palsy 3 | 674
sarcoidosis 3 | 368
Cerebrovascular disease 2 | 231
Endometriosis 2 | 535
Kidney disease 2 | 397
Prostatic Neoplasms 2 | 471
Vasculitis 2 | 64
chronic lymphocytic leukemia 2 | 244
glioblastoma multiforme 2 | 347
urothelial carcinoma 2 | 318

Tissue

Endocrine System 105 | 18,511
Nervous System 105 | 18,560
Respiratory system 105 | 17,483
Cardiovascular System 104 | 17,957
Digestive Tract 104 | 18,472
Female tissues 104 | 18,646
Liver and Pancreas 104 | 18,135
Male tissues 104 | 17,968
Skin and soft tissues 104 | 18,114
Urinary Tract 104 | 18,443
Blood and immune system 103 | 17,994

Target Family

Non-IDG 104 | 11,969
Enzyme 1 | 4,146
Epigenetic 1 | 242

PANTHER Protein Class (1)

membrane trafficking regulator... 106 | 106
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-32 SNX32 Tdark Non-IDG 0.60 0.07 75
NSFL1 cofactor p47 NSFL1C Tbio Non-IDG -0.96009 8.42 54
Sorting nexin-12 SNX12 Tbio Non-IDG -0.22432 2.17 135
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.72363 48.4 144
Ras and Rab interactor 2 RIN2 Tbio Non-IDG -1.42926 24.1 51
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG 0.27 0.49 34
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26496 23.1 128
Sorting nexin-7 SNX7 Tdark Non-IDG -0.55014 4.14 105
Sorting nexin-6 SNX6 Tbio Non-IDG -0.96991 10.2 204
Synaptogyrin-4 SYNGR4 Tdark Non-IDG 0.00000 110