Development Level

Tbio 65 | 11,651
Tdark 10 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal thoracic cage shape 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating lactate ... 1 | 3
decreased mean corpuscular hem... 1 | 50
edema 1 | 59
embryonic growth retardation 1 | 106
improved glucose tolerance 1 | 79
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 51 | 11,493
ovarian cancer 41 | 8,520
osteosarcoma 36 | 7,950
glioblastoma 34 | 5,792
medulloblastoma, large-cell 32 | 6,241
psoriasis 30 | 6,694
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 24 | 4,679
Astrocytoma, Pilocytic 23 | 3,081
group 3 medulloblastoma 22 | 4,104
adult high grade glioma 18 | 3,801
lung cancer 18 | 4,740
astrocytic glioma 17 | 2,597
lung carcinoma 16 | 2,843
oligodendroglioma 16 | 2,850
Breast cancer 15 | 3,578
Pick disease 15 | 1,894
primitive neuroectodermal tumor 15 | 3,035
subependymal giant cell astrocytoma 15 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
non-small cell lung cancer 11 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
malignant mesothelioma 10 | 3,232
pituitary cancer 10 | 1,972
dermatomyositis 9 | 966
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pediatric high grade glioma 8 | 1,064
Multiple myeloma 7 | 1,332
Waldenstrons macroglobulinemia 7 | 765
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
tuberculosis 7 | 2,010
Amyotrophic lateral sclerosis 6 | 451
Autosomal recessive predisposition 6 | 1,442
Neurodegenerative disease 6 | 414
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
spina bifida 6 | 1,074
Cancer 5 | 2,499
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
cutaneous lupus erythematosus 5 | 1,057
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
Cognitive delay 4 | 608
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
ARC syndrome 3 | 13
Alzheimer's disease 3 | 658
Bipolar Disorder 3 | 666
Botulism 3 | 24
Dull intelligence 3 | 645
Failure to gain weight 3 | 365
Hepatomegaly 3 | 285
Impaired cognition 3 | 96
Kidney disease 3 | 430
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Mental impairment 3 | 95
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Retinitis pigmentosa 24 3 | 15
Weight decreased 3 | 103
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
hereditary spastic paraplegia 3 | 318
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
sarcoidosis 3 | 370
tuberculosis and treatment for 6 months 3 | 409
Atopic dermatitis 2 | 952
Byzanthine arch palate 2 | 194
Cerebrovascular disease 2 | 238
Seizures 2 | 596
Type 2 diabetes mellitus 2 | 272
Vasculitis 2 | 80
nasopharyngeal carcinoma 2 | 1,058
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 74 | 17,369
Endocrine System 74 | 18,159
Male tissues 74 | 17,142
Female tissues 73 | 17,400
Liver and Pancreas 73 | 16,750
Nervous System 73 | 16,725
Skin and soft tissues 72 | 17,230
Urinary Tract 72 | 16,678
Respiratory system 69 | 16,393
Blood and immune system 67 | 16,909
Cardiovascular System 65 | 15,192

Target Family

Non-IDG 74 | 12,091
Enzyme 1 | 4,145

PANTHER Protein Class (1)

membrane trafficking regulator... 75 | 75
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Synaptotagmin-17 SYT17 Tbio Non-IDG -0.77330 6.07 106
Rab5 GDP/GTP exchange factor RABGEF1 Tbio Non-IDG -1.30146 21.4 78
Ras and Rab interactor 1 RIN1 Tbio Non-IDG -1.64680 53.2 124
Amyloid-beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.60681 41.4 135
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905
Ras and Rab interactor 2 RIN2 Tbio Non-IDG -1.45894 28.6 56
Lethal(2) giant larvae protein homolog 2 LLGL2 Tbio Non-IDG -0.84559 6.78 138
NSFL1 cofactor p47 NSFL1C Tbio Non-IDG -1.01934 9.42 65
Sec1 family domain-containing protein 2 SCFD2 Tdark Non-IDG -0.09123 1.24 48