Development Level

Tbio 98 | 10,625
Tdark 30 | 7,003
Tchem 21 | 1,890

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal spleen morphology 2 | 36
abnormal testis morphology 2 | 30
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased erythrocyte cell num... 2 | 43
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
enlarged heart 2 | 111
enlarged spleen 2 | 26
impaired glucose tolerance 2 | 52
increased exploration in new e... 2 | 56
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
small testis 2 | 37
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal eye size 1 | 11
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
anophthalmia 1 | 20
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
female infertility 1 | 34
hyperactivity 1 | 108
immune system phenotype 1 | 17
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 31
increased effector memory T-he... 1 | 5
increased fasted circulating g... 1 | 68
increased glycosylated hemoglo... 1 | 1
increased heart rate 1 | 17
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased memory-marker gamma-... 1 | 2
increased red blood cell distr... 1 | 21
increased spleen weight 1 | 3
male infertility 1 | 62
short tibia 1 | 82
shortened RR interval 1 | 19
straub tail 1 | 26
urinary bladder obstruction 1 | 2

Disease

ovarian cancer 83 | 8,484
osteosarcoma 79 | 7,933
medulloblastoma, large-cell 70 | 6,234
psoriasis 63 | 6,685
glioblastoma 56 | 5,572
lung cancer 53 | 4,466
atypical teratoid / rhabdoid tumor 46 | 4,369
malignant mesothelioma 37 | 3,162
primitive neuroectodermal tumor 34 | 3,031
Breast cancer 31 | 3,094
Carcinoma 31 | 2,147
pediatric high grade glioma 31 | 2,712
subependymal giant cell astrocytoma 30 | 2,287
invasive ductal carcinoma 29 | 2,950
Cancer 28 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
non-small cell lung cancer 27 | 2,798
oligodendroglioma 27 | 2,849
pilocytic astrocytoma 27 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
ependymoma 22 | 2,514
group 4 medulloblastoma 22 | 1,875
lung adenocarcinoma 22 | 2,713
astrocytic glioma 21 | 2,241
lung carcinoma 20 | 2,844
medulloblastoma 20 | 1,524
pituitary cancer 20 | 1,972
adult high grade glioma 19 | 2,148
ductal carcinoma in situ 18 | 1,745
breast carcinoma 17 | 1,614
group 3 medulloblastoma 17 | 2,254
astrocytoma 16 | 1,493
pancreatic cancer 16 | 2,300
Atopic dermatitis 15 | 944
colon cancer 15 | 1,475
tuberculosis 15 | 1,557
ulcerative colitis 15 | 2,087
Multiple myeloma 14 | 1,327
acute quadriplegic myopathy 14 | 1,157
cystic fibrosis 14 | 1,665
nasopharyngeal carcinoma 14 | 1,056
non primary Sjogren syndrome sicca 14 | 840
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Pick disease 13 | 1,893
adrenocortical carcinoma 13 | 1,427
posterior fossa group A ependymoma 13 | 1,511
dermatomyositis 12 | 933
posterior fossa group B ependymoma 12 | 1,530
Intellectual disability 11 | 573
interstitial cystitis 11 | 2,299
juvenile dermatomyositis 11 | 1,189
sonic hedgehog group medulloblastoma 11 | 1,482
tuberculosis and treatment for 6 months 11 | 686
Rheumatoid Arthritis 9 | 1,160
aldosterone-producing adenoma 9 | 664
cutaneous lupus erythematosus 9 | 1,056
atypical teratoid/rhabdoid tumor 8 | 1,095
diabetes mellitus 8 | 1,663
primary Sjogren syndrome 8 | 789
primary pancreatic ductal adenocarcinoma 8 | 1,271
Duchenne muscular dystrophy 7 | 602
Endometriosis 7 | 535
Multiple Sclerosis 7 | 498
Prostatic Neoplasms 7 | 471
Waldenstrons macroglobulinemia 7 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
gastric carcinoma 7 | 832
pancreatic carcinoma 7 | 567
spina bifida 7 | 1,064
tuberculosis and treatment for 3 months 7 | 327
Down syndrome 6 | 548
Gaucher disease type 1 6 | 171
Lung Neoplasms 6 | 171
Polycystic Ovary Syndrome 6 | 332
active Crohn's disease 6 | 918
active ulcerative colitis 6 | 477
hereditary spastic paraplegia 6 | 313
sarcoidosis 6 | 358
Amyotrophic Lateral Sclerosis 5 | 431
Glycogen storage disease 5 | 37
Liver carcinoma 5 | 217
Stomach Neoplasms 5 | 282
chronic lymphosyte leukemia 5 | 232
gastric cancer 5 | 430
hepatocellular carcinoma 5 | 532
interstitial lung disease 5 | 291
Alzheimer's disease 4 | 644
Carney complex 4 | 23
Chronic Lymphocytic Leukemia 4 | 242
Dermatitis, Allergic Contact 4 | 66
IGA Glomerulonephritis 4 | 454
Parkinson's disease 4 | 364
Peripheral vascular disease 4 | 90
Schizophrenia 4 | 501
esophageal adenocarcinoma 4 | 737
Myocardial Ischemia 3 | 169
Vascular disease 3 | 281
acute myeloid leukemia 3 | 780
nephrosclerosis 3 | 329

Tissue

Digestive Tract 148 | 18,473
Nervous System 148 | 18,561
Blood and immune system 147 | 17,995
Cardiovascular System 147 | 17,958
Endocrine System 147 | 18,512
Female tissues 147 | 18,647
Liver and Pancreas 147 | 18,136
Urinary Tract 147 | 18,444
Male tissues 146 | 17,969
Respiratory system 146 | 17,484
Skin and soft tissues 146 | 18,115

Target Family

Non-IDG 101 | 11,971
Enzyme 42 | 4,146
Kinase 6 | 634

PANTHER Protein Class (1)

kinase modulator 149 | 149
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
WD repeat-containing protein 87 WDR87 Tdark Non-IDG 0.42 0.25 12
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
C-Jun-amino-terminal kinase-interacting protein 3 MAPK8IP3 Tbio Enzyme -1.63360 51.0 128
Coiled-coil domain-containing protein 88B CCDC88B Tdark Non-IDG -0.65642 5.36 36
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
WD repeat-containing protein 75 WDR75 Tdark Non-IDG -0.40457 2.42 13
WD repeat and FYVE domain-containing protein 1 WDFY1 Tbio Non-IDG -0.67020 4.80 91
WD repeat-containing protein 81 WDR81 Tdark Non-IDG -1.18646 17.0 6