Development Level

Tbio 75 | 11,445
Tdark 15 | 6,588
Tchem 9 | 1,598

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged pancreas 1 | 2
enlarged spleen 1 | 41
enlarged thymus 1 | 5
hyperactivity 1 | 148
increased circulating bilirubi... 1 | 16
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased glycosylated hemoglo... 1 | 1
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

osteosarcoma 56 | 7,950
Carcinoma 55 | 11,493
ovarian cancer 54 | 8,520
medulloblastoma, large-cell 46 | 6,241
lung cancer 44 | 4,740
psoriasis 39 | 6,694
glioblastoma 38 | 5,792
atypical teratoid / rhabdoid tumor 36 | 5,112
malignant mesothelioma 31 | 3,232
ependymoma 30 | 4,679
primitive neuroectodermal tumor 30 | 3,035
adult high grade glioma 27 | 3,801
Cancer 24 | 2,499
group 3 medulloblastoma 24 | 4,104
non-small cell lung cancer 23 | 2,890
Breast cancer 22 | 3,578
invasive ductal carcinoma 22 | 2,951
subependymal giant cell astrocytoma 22 | 2,287
Astrocytoma, Pilocytic 21 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
breast carcinoma 17 | 1,638
group 4 medulloblastoma 17 | 1,855
lung adenocarcinoma 17 | 2,716
Kidney cancer 16 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
pituitary cancer 16 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
astrocytic glioma 14 | 2,597
cystic fibrosis 14 | 1,696
lung carcinoma 14 | 2,843
oligodendroglioma 14 | 2,850
pancreatic cancer 14 | 2,398
tuberculosis 14 | 2,010
Atopic dermatitis 13 | 952
colon cancer 13 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
adrenocortical carcinoma 12 | 1,428
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
astrocytoma 11 | 1,146
nasopharyngeal carcinoma 11 | 1,058
Multiple myeloma 10 | 1,332
Pick disease 10 | 1,894
non primary Sjogren syndrome sicca 10 | 891
dermatomyositis 9 | 966
pediatric high grade glioma 9 | 1,064
ulcerative colitis 9 | 1,819
Rheumatoid arthritis 8 | 1,191
active ulcerative colitis 8 | 764
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
Autosomal recessive predisposition 7 | 1,442
Liver Cirrhosis, Experimental 7 | 769
Polycystic ovary syndrome 7 | 360
active Crohn's disease 7 | 922
acute quadriplegic myopathy 7 | 1,158
primary Sjogren syndrome 7 | 735
Endometriosis 6 | 540
Waldenstrons macroglobulinemia 6 | 765
aldosterone-producing adenoma 6 | 665
juvenile dermatomyositis 6 | 1,187
medulloblastoma 6 | 720
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Duchenne muscular dystrophy 5 | 601
Glycogen storage disease 5 | 39
Intellectual disability 5 | 1,016
Schizophrenia 5 | 1,160
diabetes mellitus 5 | 1,728
tuberculosis and treatment for 6 months 5 | 409
Amyotrophic lateral sclerosis 4 | 451
Carcinoma, Hepatocellular 4 | 228
Gaucher disease type 1 4 | 180
Hydrocephalus 4 | 152
Liver carcinoma 4 | 240
Prostatic Neoplasms 4 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
hepatocellular carcinoma 4 | 547
hereditary spastic paraplegia 4 | 318
interstitial lung disease 4 | 298
pancreatic carcinoma 4 | 562
Chronic Lymphocytic Leukemia 3 | 262
Cognitive delay 3 | 608
Dermatitis, Allergic Contact 3 | 67
Down syndrome 3 | 499
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Heart disease 3 | 306
Immune system cancer 3 | 140
Mental and motor retardation 3 | 608
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Neurodegenerative disease 3 | 414
Peripheral vascular disease 3 | 87
Seizures 3 | 596
acute myeloid leukemia 3 | 783
chronic lymphosyte leukemia 3 | 204
progressive supranuclear palsy 3 | 676
tuberculosis and treatment for 3 months 3 | 179

Tissue

Digestive Tract 96 | 17,369
Endocrine System 96 | 18,159
Female tissues 95 | 17,400
Liver and Pancreas 95 | 16,750
Skin and soft tissues 95 | 17,230
Male tissues 94 | 17,142
Nervous System 94 | 16,725
Respiratory system 94 | 16,393
Blood and immune system 93 | 16,909
Urinary Tract 92 | 16,678
Cardiovascular System 89 | 15,192

Target Family

Non-IDG 67 | 12,091
Enzyme 26 | 4,145
Kinase 6 | 634

PANTHER Protein Class (1)

kinase modulator 99 | 99
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B3 CCNB3 Tbio Non-IDG -1.07824 12.1 272
Protein Hook homolog 1 HOOK1 Tbio Non-IDG -1.16190 13.1 187
Regulation of nuclear pre-mRNA domain-containing protein 1A RPRD1A Tbio Non-IDG -0.86647 8.54 81
MOB-like protein phocein MOB4 Tbio Non-IDG -1.36459 24.7 114
MOB kinase activator 3C MOB3C Tdark Enzyme 0.48 0.14 63
Coiled-coil domain-containing protein 88B CCDC88B Tdark Non-IDG -0.77694 6.44 39
Centrosome-associated protein CEP250 CEP250 Tbio Non-IDG -0.75187 5.22 35
Lipoma-preferred partner LPP Tbio Non-IDG -2.77949 582.6 164
eIF-2-alpha kinase activator GCN1 GCN1 Tdark Non-IDG -1.38567 23.9 50
Putative uncharacterized protein MYH16 MYH16 Tbio Non-IDG 0.00000 0