Development Level

Tbio 84 | 11,651
Tclin 55 | 612
Tchem 36 | 1,388
Tdark 11 | 6,593

Collection

Ion Channel: IDG Consortium (T... 41 | 99
RFA-RM-18-021 40 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased vertical activity 6 | 208
abnormal gait 4 | 69
enlarged heart 4 | 210
increased startle reflex 4 | 112
preweaning lethality, incomple... 4 | 499
abnormal epididymis morphology 3 | 42
decreased eosinophil cell numb... 3 | 24
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal pancreas morphology 2 | 13
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased circulating alkaline... 2 | 46
decreased circulating amylase ... 2 | 28
decreased circulating glycerol... 2 | 16
decreased grip strength 2 | 116
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
enlarged epididymis 2 | 31
hydrometra 2 | 53
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal forelimb morphology 1 | 2
abnormal joint morphology 1 | 23
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal pelvic girdle bone mo... 1 | 12
abnormal response to new envir... 1 | 10
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
brachydactyly 1 | 19
cataract 1 | 92
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
mammalian phenotype 1 | 17
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small epididymis 1 | 3
small heart 1 | 10
small liver 1 | 8
small testis 1 | 58
syndactyly 1 | 23
thick ventricular wall 1 | 7
tremors 1 | 39

Disease

Carcinoma 146 | 11,493
psoriasis 79 | 6,694
medulloblastoma, large-cell 77 | 6,241
atypical teratoid / rhabdoid tumor 71 | 5,112
glioblastoma 70 | 5,792
osteosarcoma 67 | 7,950
Kidney cancer 58 | 2,613
adult high grade glioma 57 | 3,801
ependymoma 57 | 4,679
ovarian cancer 55 | 8,520
Epilepsy 52 | 792
Astrocytoma, Pilocytic 51 | 3,081
lung cancer 49 | 4,740
primitive neuroectodermal tumor 49 | 3,035
oligodendroglioma 47 | 2,850
group 3 medulloblastoma 44 | 4,104
astrocytic glioma 40 | 2,597
lung carcinoma 39 | 2,843
Breast cancer 38 | 3,578
subependymal giant cell astrocytoma 38 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
Pick disease 33 | 1,894
Schizophrenia 32 | 1,160
Bipolar Disorder 31 | 666
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
lung adenocarcinoma 30 | 2,716
malignant mesothelioma 30 | 3,232
interstitial cystitis 29 | 2,312
Tonic-clonic epilepsy 26 | 47
cystic fibrosis 26 | 1,696
pituitary cancer 26 | 1,972
Autistic Disorder 24 | 364
colon cancer 24 | 1,478
General anesthesia 23 | 53
Seizures 22 | 596
non-small cell lung cancer 22 | 2,890
pancreatic cancer 22 | 2,398
invasive ductal carcinoma 21 | 2,951
Autosomal recessive predisposition 20 | 1,442
Alcoholic Intoxication, Chronic 19 | 289
Local anesthesia 19 | 40
Intellectual disability 18 | 1,016
Muscle hypotonia 18 | 571
Nicotine dependence 18 | 54
Anxiety 17 | 136
group 4 medulloblastoma 17 | 1,855
Alcohol dependence 16 | 107
Atrial Fibrillation 16 | 124
Hypertension 16 | 396
Insomnia 16 | 20
Liver cancer 16 | 604
Status Epilepticus 16 | 98
Cancer 15 | 2,499
Irritable bowel syndrome 15 | 60
Spasticity 15 | 26
ductal carcinoma in situ 15 | 1,745
ulcerative colitis 15 | 1,819
Depressive disorder 14 | 409
Lennox-Gastaut syndrome 14 | 34
Melanoma 14 | 711
tuberculosis 14 | 2,010
Constipation 13 | 181
Dysuria 13 | 26
Epilepsy characterized by intractable complex partial seizures 13 | 28
Infantile onset 13 | 238
Localization-related epilepsy 13 | 13
Neuropathy 13 | 261
Sedation as Adjunct to Anesthesia 13 | 15
Urinary Tract Irritation 13 | 24
adrenocortical carcinoma 13 | 1,428
Cerebellar Ataxia 12 | 304
Mental Depression 12 | 333
cutaneous lupus erythematosus 12 | 1,057
nasopharyngeal carcinoma 12 | 1,058
Bipolar disorder in remission 11 | 19
Cough 11 | 25
Dull intelligence 11 | 645
Gastroesophageal reflux disease 11 | 110
Hypertensive disease 11 | 292
Hypertensive disorder 11 | 57
Itching of skin 11 | 18
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Minor Skin Wound Pain 11 | 12
Mouth Irritation 11 | 12
Poor school performance 11 | 645
Simple partial seizure 11 | 26
Skin cancer 11 | 469
Skin irritation 11 | 12
Suppression of the Gag Reflex 11 | 12
Tinea corporis 11 | 25
Tinea pedis 11 | 29
Tonic-clonic seizure 11 | 11
Ventricular arrhythmia 11 | 27
Feeding difficulties in infancy 10 | 175
Mental and motor retardation 10 | 608
diabetes mellitus 10 | 1,728
spina bifida 10 | 1,074

Tissue

Endocrine System 178 | 18,159
Nervous System 168 | 16,725
Digestive Tract 166 | 17,369
Female tissues 160 | 17,400
Skin and soft tissues 160 | 17,230
Male tissues 158 | 17,142
Blood and immune system 156 | 16,909
Urinary Tract 154 | 16,678
Liver and Pancreas 150 | 16,750
Respiratory system 140 | 16,393
Cardiovascular System 123 | 15,192

Target Family

Ion Channel 147 | 344
Non-IDG 16 | 12,091
Transporter 14 | 473
GPCR 5 | 408
Enzyme 3 | 4,145
Kinase 1 | 634

PANTHER Protein Class (1)

ion channel 186 | 186
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107
Protein tweety homolog 3 TTYH3 Tbio Ion Channel -0.17609 1.56 17
BTB/POZ domain-containing protein KCTD3 KCTD3 Tdark Non-IDG -0.32486 1.06 100
Voltage-dependent calcium channel gamma-2 subunit CACNG2 Tbio Ion Channel -1.92203 89.6 173
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.25002 172.0 220
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.10269 131.1 212
Junctional adhesion molecule-like JAML Tbio Non-IDG -1.66747 47.0 202
H(+)/Cl(-) exchange transporter 5 CLCN5 Tbio Ion Channel -2.32606 225.3 156