Development Level

Tbio 77 | 11,178
Tdark 9 | 6,569
Tchem 1 | 1,885

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased total body fat amoun... 3 | 207
preweaning lethality, complete... 3 | 979
abnormal craniofacial morpholo... 2 | 33
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
decreased grip strength 2 | 116
enlarged heart 2 | 210
increased body length 2 | 32
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
long tibia 2 | 25
small superior vagus ganglion 2 | 74
abnormal abdominal wall morpho... 1 | 1
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent vibrissae 1 | 12
cleft palate 1 | 8
corneal opacity 1 | 32
corneal vascularization 1 | 6
cyanosis 1 | 7
decreased caudal vertebrae num... 1 | 53
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased hemoglobin content 1 | 45
narrow eye opening 1 | 12
rib fusion 1 | 1
shortened QT interval 1 | 4
syndactyly 1 | 23
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 38 | 11,192
medulloblastoma, large-cell 27 | 6,086
ovarian cancer 25 | 8,297
osteosarcoma 24 | 7,766
psoriasis 24 | 6,514
glioblastoma 22 | 5,635
lung cancer 22 | 4,607
atypical teratoid / rhabdoid tumor 20 | 4,971
malignant mesothelioma 20 | 3,135
Cancer 17 | 2,388
Breast cancer 16 | 3,469
cystic fibrosis 16 | 1,629
primitive neuroectodermal tumor 16 | 2,957
invasive ductal carcinoma 15 | 2,867
Astrocytoma, Pilocytic 14 | 3,006
adult high grade glioma 13 | 3,701
ependymoma 13 | 4,559
non-small cell lung cancer 13 | 2,799
Cleft Palate 11 | 265
group 3 medulloblastoma 11 | 4,002
astrocytic glioma 10 | 2,530
ductal carcinoma in situ 10 | 1,686
interstitial cystitis 10 | 2,237
oligodendroglioma 10 | 2,768
Craniofacial Abnormalities 9 | 141
breast carcinoma 9 | 1,589
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,902
lung adenocarcinoma 9 | 2,627
pituitary cancer 9 | 1,915
Cognitive delay 8 | 596
Global developmental delay 8 | 596
Mental and motor retardation 8 | 596
cutaneous lupus erythematosus 8 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
Autosomal recessive predisposition 7 | 1,407
Cleft Lip 7 | 141
colon cancer 7 | 1,428
group 4 medulloblastoma 7 | 1,806
pediatric high grade glioma 7 | 1,035
Tooth agenesis 6 | 42
Uranostaphyloschisis 6 | 162
medulloblastoma 6 | 702
pancreatic cancer 6 | 2,322
spina bifida 6 | 1,053
Congenital heart disease 5 | 91
Lung diseases 5 | 47
Microphthalmia 5 | 72
Muscle hypotonia 5 | 562
Sensorineural Hearing Loss (disorder) 5 | 281
Syndactyly 5 | 88
active ulcerative colitis 5 | 736
gastric carcinoma 5 | 781
Autistic Disorder 4 | 358
Bipolar Disorder 4 | 646
Epilepsy 4 | 775
Intellectual disability 4 | 998
Schizophrenia 4 | 1,136
Seizures 4 | 584
Split hand-foot malformation 4 | 18
Ventricular Septal Defects 4 | 113
adrenocortical carcinoma 4 | 1,385
dermatomyositis 4 | 941
diabetes mellitus 4 | 1,683
lung carcinoma 4 | 2,755
subependymal giant cell astrocytoma 4 | 2,230
ulcerative colitis 4 | 1,765
Abnormally small eyeball 3 | 94
Agenesis of corpus callosum 3 | 79
Barrett's esophagus 3 | 173
Byzanthine arch palate 3 | 194
Constipation 3 | 174
Decreased size of eyeball 3 | 94
Dull intelligence 3 | 634
Frontal bossing 3 | 154
Hernia, Inguinal 3 | 88
Holoprosencephaly 3 | 52
Hypoplastic mandible condyle 3 | 273
Hypotrophic malar bone 3 | 129
Idiopathic scoliosis 3 | 31
Low intelligence 3 | 634
Malar flattening 3 | 129
Mandibular hypoplasia 3 | 273
Mental deficiency 3 | 634
Myopia 3 | 175
Periventricular nodular heterotopia 3 | 30
Poor school performance 3 | 634
Rapp-Hodgkin syndrome 3 | 6
Renal agenesis 3 | 29
Rheumatoid arthritis 3 | 1,156
Short stature 3 | 514
Small head 3 | 366
Spastic Quadriplegia 3 | 41
Tetralogy of Fallot 3 | 66
Velocardiofacial syndrome 3 | 46
Waldenstrons macroglobulinemia 3 | 742
aldosterone-producing adenoma 3 | 646
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,911
posterior fossa group A ependymoma 3 | 456
sonic hedgehog group medulloblastoma 3 | 459

Tissue

Endocrine System 78 | 18,159
Digestive Tract 68 | 17,369
Skin and soft tissues 66 | 17,230
Female tissues 62 | 17,400
Blood and immune system 60 | 16,909
Male tissues 59 | 17,142
Liver and Pancreas 57 | 16,750
Nervous System 57 | 16,725
Urinary Tract 52 | 16,678
Respiratory system 51 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Transcription Factor 81 | 1,400
Non-IDG 6 | 12,091

PANTHER Protein Class (1)

helix-turn-helix transcription... 87 | 87
RNA binding protein 476 | 476
kinase 357 | 357
DNA binding protein 338 | 338
protease 224 | 224
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
protease inhibitor 196 | 196
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
transcription cofactor 96 | 96
ubiquitin-protein ligase 83 | 83
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
zinc finger transcription fact... 50 | 50
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
basic helix-loop-helix transcr... 42 | 42
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
nucleotidyltransferase 20 | 20
transaminase 18 | 18
metalloprotease 16 | 16
carbohydrate transporter 15 | 15
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
basic leucine zipper transcrip... 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
glycosidase 11 | 11
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
phosphodiesterase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
HMG box transcription factor 1 | 1
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein NANOG NANOG Tchem Transcription Factor -2.94914 1130.5 958
Homeobox protein Nkx-2.2 NKX2-2 Tbio Transcription Factor -2.06202 108.0 379
NK1 transcription factor-related protein 1 NKX1-1 Tdark Transcription Factor -0.30821 1.97 79
Homeobox protein engrailed-1 EN1 Tbio Transcription Factor -2.44551 264.6 188
Homeobox protein EMX1 EMX1 Tbio Transcription Factor -1.76097 51.7 154
Homeobox protein EMX2 EMX2 Tbio Transcription Factor -2.04282 110.8 265
Homeobox protein Nkx-3.2 NKX3-2 Tbio Transcription Factor -1.63808 48.5 142
Putative homeobox protein NANOG2 NANOGP1 Tdark Non-IDG -0.35402 2.12 0
Iroquois-class homeodomain protein IRX-5 IRX5 Tbio Transcription Factor -1.54616 33.4 196
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.84681 686.8 212