Development Level

Tbio 87 | 10,625
Tdark 31 | 7,003
Tchem 6 | 1,890

IMPC Term

preweaning lethality, complete... 15 | 633
embryonic lethality prior to o... 7 | 148
decreased lean body mass 5 | 195
embryonic lethality prior to t... 5 | 187
abnormal behavior 3 | 226
increased grip strength 3 | 83
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
decreased body length 2 | 108
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
increased circulating alkaline... 2 | 119
abnormal behavioral response t... 1 | 52
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hindbrain development 1 | 24
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal tooth morphology 1 | 24
anophthalmia 1 | 20
decreased KLRG1+ CD4 alpha bet... 1 | 2
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating fructosa... 1 | 31
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean platelet volume 1 | 12
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
hyperactivity 1 | 108
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating potassiu... 1 | 31
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased total body fat amoun... 1 | 57
male infertility 1 | 62
microphthalmia 1 | 15
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small testis 1 | 37
waved hair 1 | 1

Disease

ovarian cancer 68 | 8,484
osteosarcoma 50 | 7,933
medulloblastoma, large-cell 49 | 6,234
psoriasis 42 | 6,685
glioblastoma 40 | 5,572
Carcinoma 39 | 2,147
lung cancer 35 | 4,466
group 3 medulloblastoma 30 | 2,254
primitive neuroectodermal tumor 29 | 3,031
atypical teratoid / rhabdoid tumor 28 | 4,369
Cancer 26 | 2,346
malignant mesothelioma 24 | 3,162
pediatric high grade glioma 21 | 2,712
Breast cancer 20 | 3,094
oligodendroglioma 20 | 2,849
non-small cell lung cancer 16 | 2,798
Multiple myeloma 15 | 1,327
ependymoma 15 | 2,514
astrocytic glioma 14 | 2,241
diabetes mellitus 14 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
lung adenocarcinoma 14 | 2,713
Waldenstrons macroglobulinemia 13 | 765
colon cancer 13 | 1,475
juvenile dermatomyositis 13 | 1,189
Intellectual disability 12 | 573
Rheumatoid Arthritis 12 | 1,160
adrenocortical carcinoma 12 | 1,427
invasive ductal carcinoma 12 | 2,950
Baller-Gerold syndrome 11 | 14
Cockayne syndrome 11 | 54
Rothmund-Thomson syndrome 11 | 22
acute quadriplegic myopathy 11 | 1,157
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
pilocytic astrocytoma 11 | 3,086
Pick disease 10 | 1,893
astrocytoma 10 | 1,493
medulloblastoma 10 | 1,524
sonic hedgehog group medulloblastoma 10 | 1,482
dermatomyositis 9 | 933
group 4 medulloblastoma 9 | 1,875
Bloom syndrome 8 | 30
Fanconi's anemia 8 | 50
Werner syndrome 8 | 29
atypical teratoid/rhabdoid tumor 8 | 1,095
nasopharyngeal carcinoma 8 | 1,056
progressive supranuclear palsy 8 | 674
subependymal giant cell astrocytoma 8 | 2,287
Photosensitive trichothiodystrophy 7 | 24
Warsaw breakage syndrome 7 | 12
adult high grade glioma 7 | 2,148
non primary Sjogren syndrome sicca 7 | 840
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 1,511
Xeroderma pigmentosum 6 | 41
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
ulcerative colitis 6 | 2,087
Peripheral Neuropathy 5 | 303
tuberculosis 5 | 1,557
tuberculosis and treatment for 6 months 5 | 686
Endometriosis 4 | 535
Microcephaly 4 | 149
Neuroblastoma 4 | 78
Neuropathy 4 | 210
Rapadilino syndrome 4 | 7
acute myeloid leukemia 4 | 780
aldosterone-producing adenoma 4 | 664
cystic fibrosis 4 | 1,665
ductal carcinoma in situ 4 | 1,745
lung carcinoma 4 | 2,844
primary Sjogren syndrome 4 | 789
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
Adenoid Cystic Carcinoma 3 | 99
Amyotrophic Lateral Sclerosis 3 | 431
Anemia 3 | 252
CHARGE syndrome 3 | 23
Choanal atresia 3 | 19
Crohn's disease 3 | 304
Gaucher disease type 1 3 | 171
IGA Glomerulonephritis 3 | 454
Kidney disease 3 | 396
Male infertility 3 | 170
Neurodegenerative disease 3 | 383
PITT-HOPKINS SYNDROME 3 | 21
Roberts syndrome 3 | 16
Schimke immuno-osseous dysplasia 3 | 9
Spondyloepiphyseal dysplasia with congenital joint dislocations 3 | 12
breast carcinoma 3 | 1,614
gastric cancer 3 | 430
hereditary spastic paraplegia 3 | 313
interstitial lung disease 3 | 291
posterior fossa group B ependymoma 3 | 1,530
Polycystic Ovary Syndrome 2 | 332
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 532
pancreatic carcinoma 2 | 567

Tissue

Blood and immune system 122 | 17,995
Male tissues 122 | 17,969
Nervous System 122 | 18,561
Female tissues 121 | 18,647
Cardiovascular System 120 | 17,958
Digestive Tract 119 | 18,473
Liver and Pancreas 119 | 18,136
Endocrine System 118 | 18,512
Urinary Tract 118 | 18,444
Respiratory system 117 | 17,484
Skin and soft tissues 117 | 18,115

Target Family

Enzyme 74 | 4,146
Non-IDG 36 | 11,971
Epigenetic 14 | 242

PANTHER Protein Class (1)

helicase 124 | 124
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
glycosyltransferase 191 | 191
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 62 TMEM62 Tdark Non-IDG 0.30 0.75 11
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.84578 76.6 72
ATP-dependent RNA helicase DDX55 DDX55 Tdark Enzyme 0.48 0.33 93
ATP-dependent RNA helicase DDX3Y DDX3Y Tbio Enzyme -1.73057 61.1 142
DNA-binding protein SMUBP-2 IGHMBP2 Tbio Non-IDG -1.84895 75.2 35
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.21804 176.4 137
Putative ATP-dependent RNA helicase TDRD12 TDRD12 Tdark Epigenetic -0.68009 4.78 17
Fanconi anemia group M protein FANCM Tbio Non-IDG -1.62924 51.7 75
DNA helicase B HELB Tbio Enzyme -2.75456 596.5 20
DNA excision repair protein ERCC-6-like ERCC6L Tbio Non-IDG -1.98573 105.5 123