Development Level

Tbio 49 | 11,445
Tdark 24 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 4 | 239
abnormal behavior 3 | 298
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
increased total body fat amoun... 3 | 134
abnormal embryo size 2 | 220
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal embryo turning 1 | 31
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased monocyte cell number 1 | 8
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
increased aggression 1 | 4
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased urine magnesium leve... 1 | 2
male infertility 1 | 123
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 62 | 11,493
ovarian cancer 37 | 8,520
osteosarcoma 35 | 7,950
medulloblastoma, large-cell 29 | 6,241
group 3 medulloblastoma 28 | 4,104
Kidney cancer 26 | 2,613
glioblastoma 22 | 5,792
atypical teratoid / rhabdoid tumor 21 | 5,112
lung cancer 21 | 4,740
primitive neuroectodermal tumor 20 | 3,035
psoriasis 18 | 6,694
malignant mesothelioma 17 | 3,232
Breast cancer 16 | 3,578
Cancer 14 | 2,499
ependymoma 13 | 4,679
Cockayne syndrome 10 | 60
Multiple myeloma 10 | 1,332
adult high grade glioma 10 | 3,801
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
Autosomal recessive predisposition 9 | 1,442
Baller-Gerold syndrome 9 | 12
Intellectual disability 9 | 1,016
Waldenstrons macroglobulinemia 9 | 765
astrocytic glioma 9 | 2,597
colon cancer 9 | 1,478
oligodendroglioma 9 | 2,850
Rothmund-Thomson syndrome 8 | 19
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pediatric high grade glioma 8 | 1,064
Dull intelligence 7 | 645
Fanconi anemia 7 | 56
Liver cancer 7 | 604
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Photosensitive trichothiodystrophy 7 | 30
Poor school performance 7 | 645
Short stature 7 | 531
Small head 7 | 374
Warsaw breakage syndrome 7 | 11
Werner syndrome 7 | 29
adrenocortical carcinoma 7 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
juvenile dermatomyositis 7 | 1,187
nasopharyngeal carcinoma 7 | 1,058
Astrocytoma, Pilocytic 6 | 3,081
Fetal Growth Retardation 6 | 189
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Rheumatoid arthritis 6 | 1,191
Xeroderma pigmentosum group D 6 | 33
acute quadriplegic myopathy 6 | 1,158
dermatomyositis 6 | 966
Acute leukemia 5 | 15
Bloom syndrome 5 | 29
Cognitive delay 5 | 608
Congenital deafness 5 | 185
Cryptorchidism 5 | 296
Deafness 5 | 198
Global developmental delay 5 | 608
Hearing Loss, Partial 5 | 185
Mental and motor retardation 5 | 608
Pick disease 5 | 1,894
diabetes mellitus 5 | 1,728
hearing impairment 5 | 199
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Atrophic condition of skin 4 | 25
Cataract 4 | 297
Cerebellar Ataxia 4 | 304
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Hypogonadism 4 | 173
Lens Opacities 4 | 231
Melanoma 4 | 711
Pediatric failure to thrive 4 | 365
Rapadilino syndrome 4 | 7
Seizures 4 | 596
Strabismus 4 | 270
Telangiectasia of the skin 4 | 39
Xeroderma pigmentosum 4 | 43
astrocytoma 4 | 1,146
pancreatic cancer 4 | 2,398
Abnormally small eyeball 3 | 97
Anemia 3 | 365
Decreased size of eyeball 3 | 97
Endometriosis 3 | 540
Hypoplastic mandible condyle 3 | 275
Microcephaly 3 | 166
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
medulloblastoma 3 | 720
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 71 | 18,159
Nervous System 66 | 16,725
Respiratory system 65 | 16,393
Cardiovascular System 63 | 15,192
Digestive Tract 63 | 17,369
Skin and soft tissues 63 | 17,230
Blood and immune system 61 | 16,909
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Urinary Tract 61 | 16,678

Target Family

Enzyme 37 | 4,145
Non-IDG 35 | 12,091
Epigenetic 3 | 242

PANTHER Protein Class (1)

helicase 75 | 75
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 DHX15 Tbio Enzyme -1.74929 55.5 106
Probable helicase with zinc finger domain HELZ Tbio Enzyme -1.50209 22.1 63
Helicase with zinc finger domain 2 HELZ2 Tdark Enzyme -0.50849 4.27 30
RNA helicase Mov10l1 MOV10L1 Tbio Enzyme -0.73306 5.20 57
Fanconi anemia group J protein BRIP1 Tbio Non-IDG -1.81875 78.3 223
ATPase WRNIP1 WRNIP1 Tbio Enzyme -2.55209 340.4 166