Development Level

Tbio 86 | 11,445
Tdark 8 | 6,588
Tchem 7 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 3 | 278
increased mean corpuscular vol... 3 | 92
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased spleen weight 1 | 10
edema 1 | 59
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 50 | 11,493
Cancer 46 | 2,499
psoriasis 43 | 6,694
ovarian cancer 40 | 8,520
lung cancer 39 | 4,740
malignant mesothelioma 35 | 3,232
osteosarcoma 34 | 7,950
glioblastoma 33 | 5,792
Breast cancer 32 | 3,578
ependymoma 31 | 4,679
atypical teratoid / rhabdoid tumor 29 | 5,112
lung adenocarcinoma 26 | 2,716
cystic fibrosis 25 | 1,696
interstitial cystitis 24 | 2,312
medulloblastoma, large-cell 24 | 6,241
adult high grade glioma 23 | 3,801
diabetes mellitus 22 | 1,728
invasive ductal carcinoma 22 | 2,951
lung carcinoma 21 | 2,843
non-small cell lung cancer 21 | 2,890
group 3 medulloblastoma 20 | 4,104
Astrocytoma, Pilocytic 19 | 3,081
pituitary cancer 19 | 1,972
ductal carcinoma in situ 18 | 1,745
oligodendroglioma 17 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
pancreatic cancer 16 | 2,398
Cleft Palate 15 | 271
colon cancer 15 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
ulcerative colitis 15 | 1,819
breast carcinoma 14 | 1,638
group 4 medulloblastoma 14 | 1,855
Bipolar Disorder 13 | 666
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
primitive neuroectodermal tumor 13 | 3,035
tuberculosis 13 | 2,010
Breast Neoplasms 12 | 445
Mammary Neoplasms 12 | 425
astrocytic glioma 12 | 2,597
gastric carcinoma 12 | 807
spina bifida 12 | 1,074
Autosomal recessive predisposition 11 | 1,442
Cleft Lip 11 | 141
Depressive disorder 11 | 409
Osteoarthritis 11 | 184
Pulmonary Fibrosis 11 | 106
Schizophrenia 11 | 1,160
Atopic dermatitis 10 | 952
Liver Cirrhosis, Experimental 10 | 769
Osteoporosis 10 | 363
Carcinoma, Hepatocellular 9 | 228
Liver carcinoma 9 | 240
Parkinson's disease 9 | 392
Rheumatoid arthritis 9 | 1,191
cutaneous lupus erythematosus 9 | 1,057
fibroadenoma 9 | 559
subependymal giant cell astrocytoma 9 | 2,287
Alzheimer's disease 8 | 658
Atherosclerosis 8 | 291
Coronary artery disease 8 | 268
Down syndrome 8 | 499
Kidney disease 8 | 430
Mental Depression 8 | 333
Neuropathy 8 | 261
nasopharyngeal carcinoma 8 | 1,058
non-small cell lung carcinoma 8 | 317
Diabetic retinopathy 7 | 56
Endometriosis 7 | 540
Heart disease 7 | 306
Kidney cancer 7 | 2,613
Obesity 7 | 678
Pick disease 7 | 1,894
Polycystic ovary syndrome 7 | 360
Prostatic Neoplasms 7 | 495
Short stature 7 | 531
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
nephrosclerosis 7 | 333
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary pancreatic ductal adenocarcinoma 7 | 1,109
Amyotrophic lateral sclerosis 6 | 451
Arthritis, Rheumatoid 6 | 174
Asthma 6 | 385
Downward slant of palpebral fissure 6 | 158
Glaucoma 6 | 239
Inflammation 6 | 120
Major Depressive Disorder 6 | 301
Nerve Degeneration 6 | 121
Neurodegenerative disease 6 | 414
Proliferative vitreoretinopathy 6 | 17
Stomach Neoplasms 6 | 300
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
chronic rhinosinusitis 6 | 512
head and neck cancer 6 | 271
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562

Tissue

Endocrine System 101 | 18,159
Female tissues 96 | 17,400
Digestive Tract 95 | 17,369
Liver and Pancreas 93 | 16,750
Skin and soft tissues 93 | 17,230
Male tissues 92 | 17,142
Urinary Tract 92 | 16,678
Blood and immune system 90 | 16,909
Nervous System 90 | 16,725
Respiratory system 88 | 16,393
Cardiovascular System 84 | 15,192

Target Family

Non-IDG 103 | 12,091
Enzyme 1 | 4,145

PANTHER Protein Class (1)

growth factor 104 | 104
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
cTAGE family member 15 CTAGE15 Tdark Non-IDG 0.00000 12
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Neurturin NRTN Tbio Non-IDG -2.21792 170.4 331
Melanoma inhibitory activity protein 2 CTAGE5 Tbio Non-IDG 0.00000 91
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.89822 84.6 146
cTAGE family member 4 CTAGE8 Tdark Non-IDG 0.00000 54
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735