Development Level

Tbio 121 | 10,625
Tdark 49 | 7,003
Tchem 19 | 1,890
Tclin 2 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
embryonic lethality prior to t... 3 | 187
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
decreased eosinophil cell numb... 2 | 41
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased exploration in new e... 2 | 56
abnormal behavioral response t... 1 | 52
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal pelvic girdle bone mo... 1 | 11
abnormal tail movements 1 | 12
absent vibrissae 1 | 14
cataract 1 | 26
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased blood urea nitrogen ... 1 | 31
decreased circulating alanine ... 1 | 53
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hyperactivity 1 | 108
increased CD8-positive, alpha-... 1 | 11
increased KLRG1-positive NK ce... 1 | 9
increased Ly6C high monocyte n... 1 | 12
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating glycerol... 1 | 11
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased total body fat amoun... 1 | 57
long tibia 1 | 13
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened QT interval 1 | 4
small adrenal glands 1 | 15
small spleen 1 | 11

Disease

ovarian cancer 88 | 8,492
osteosarcoma 82 | 7,933
psoriasis 65 | 6,685
glioblastoma 58 | 5,572
medulloblastoma, large-cell 50 | 6,234
atypical teratoid / rhabdoid tumor 49 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,988
lung adenocarcinoma 41 | 2,714
pilocytic astrocytoma 39 | 3,086
lung cancer 38 | 4,473
Breast cancer 33 | 3,099
pituitary cancer 29 | 1,972
malignant mesothelioma 27 | 3,163
subependymal giant cell astrocytoma 27 | 2,287
lung carcinoma 26 | 2,844
pancreatic cancer 26 | 2,300
interstitial cystitis 25 | 2,299
primitive neuroectodermal tumor 25 | 3,031
group 3 medulloblastoma 24 | 2,254
invasive ductal carcinoma 24 | 2,950
astrocytic glioma 23 | 2,241
non-small cell lung cancer 23 | 2,798
oligodendroglioma 23 | 2,849
pediatric high grade glioma 23 | 2,712
group 4 medulloblastoma 22 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
posterior fossa group A ependymoma 22 | 1,511
adult high grade glioma 21 | 2,148
cystic fibrosis 21 | 1,670
ulcerative colitis 21 | 2,087
ependymoma 20 | 2,514
active Crohn's disease 19 | 918
Multiple myeloma 18 | 1,328
Pick disease 18 | 1,893
colon cancer 17 | 1,475
posterior fossa group B ependymoma 16 | 1,530
Cancer 15 | 2,346
Carcinoma 15 | 2,147
Congenital disorder of glycosylation 15 | 53
breast carcinoma 15 | 1,614
tuberculosis 15 | 1,563
astrocytoma 14 | 1,493
ductal carcinoma in situ 14 | 1,745
medulloblastoma 14 | 1,524
Rheumatoid Arthritis 13 | 1,171
atypical teratoid/rhabdoid tumor 13 | 1,095
spina bifida 13 | 1,064
diabetes mellitus 12 | 1,663
gastric carcinoma 12 | 832
juvenile dermatomyositis 12 | 1,189
primary pancreatic ductal adenocarcinoma 12 | 1,271
Walker-Warburg syndrome 11 | 18
non primary Sjogren syndrome sicca 11 | 840
active ulcerative colitis 10 | 477
cutaneous lupus erythematosus 10 | 1,056
nasopharyngeal carcinoma 10 | 1,056
sonic hedgehog group medulloblastoma 10 | 1,482
Atopic dermatitis 9 | 944
Intellectual disability 9 | 573
Lissencephaly 9 | 61
Prostatic Neoplasms 9 | 471
non-small cell lung carcinoma 9 | 413
Congenital muscular dystrophy 8 | 25
IGA Glomerulonephritis 8 | 454
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,157
adrenocortical carcinoma 8 | 1,427
esophageal adenocarcinoma 8 | 737
Anemia 7 | 252
Bilirubin metabolic disorder 7 | 39
Muscular dystrophy 7 | 48
Sickle Cell Anemia 7 | 54
Walker-Warburg congenital muscular dystrophy 7 | 14
aldosterone-producing adenoma 7 | 664
facioscapulohumeral dystrophy 7 | 286
fibroadenoma 7 | 557
pancreatic carcinoma 7 | 567
progressive supranuclear palsy 7 | 674
Exostosis 6 | 15
Hydrocephalus 6 | 60
Schizophrenia 6 | 503
acute myeloid leukemia 6 | 785
dermatomyositis 6 | 967
primary Sjogren syndrome 6 | 789
Amyotrophic Lateral Sclerosis 5 | 432
Duchenne muscular dystrophy 5 | 602
Endometriosis 5 | 535
Muscle eye brain disease 5 | 8
Muscle-eye-brain disease 5 | 8
Obesity 5 | 616
Pericholangitis 5 | 7
chronic rhinosinusitis 5 | 512
gastric cancer 5 | 436
hepatocellular carcinoma 5 | 550
Alzheimer's disease 4 | 644
Attention deficit hyperactivity disorder 4 | 156
glioblastoma multiforme 4 | 347
tuberculosis and treatment for 6 months 4 | 686

Tissue

Digestive Tract 190 | 18,473
Liver and Pancreas 187 | 18,136
Urinary Tract 187 | 18,444
Blood and immune system 186 | 17,995
Female tissues 186 | 18,647
Endocrine System 185 | 18,512
Nervous System 185 | 18,561
Skin and soft tissues 185 | 18,115
Male tissues 180 | 17,969
Cardiovascular System 177 | 17,958
Respiratory system 175 | 17,484

Target Family

Enzyme 166 | 4,146
Non-IDG 25 | 11,969

PANTHER Protein Class (1)

glycosyltransferase 191 | 191
DNA binding protein 527 | 527
kinase 502 | 502
RNA binding protein 490 | 490
zinc finger transcription fact... 403 | 403
protease 375 | 375
actin family cytoskeletal prot... 342 | 342
G-protein modulator 330 | 330
G-protein coupled receptor 325 | 325
ion channel 304 | 304
dehydrogenase 239 | 239
phosphatase 230 | 230
helix-turn-helix transcription... 221 | 221
microtubule family cytoskeleta... 211 | 211
G-protein 193 | 193
ubiquitin-protein ligase 186 | 186
cytokine 175 | 175
protease inhibitor 167 | 167
immunoglobulin receptor superf... 162 | 162
peptide hormone 162 | 162
nuclease 152 | 152
kinase modulator 149 | 149
cation transporter 139 | 139
transcription cofactor 139 | 139
membrane-bound signaling molec... 125 | 125
helicase 124 | 124
growth factor 109 | 109
cadherin 107 | 107
membrane trafficking regulator... 106 | 106
acetyltransferase 91 | 91
extracellular matrix glycoprot... 85 | 85
intermediate filament 83 | 83
extracellular matrix structura... 75 | 75
antibacterial response protein 74 | 74
basic helix-loop-helix transcr... 74 | 74
oxygenase 73 | 73
acyltransferase 63 | 63
cytokine receptor 60 | 60
intracellular calcium-sensing ... 60 | 60
methyltransferase 60 | 60
mitochondrial carrier protein 58 | 58
lipase 55 | 55
esterase 54 | 54
phosphatase modulator 53 | 53
carbohydrate transporter 46 | 46
nuclear hormone receptor 46 | 46
major histocompatibility compl... 45 | 45
reductase 44 | 44
dehydratase 42 | 42
ATP-binding cassette (ABC) tra... 41 | 41
SNARE protein 40 | 40
vesicle coat protein 40 | 40
oxidase 39 | 39
amino acid transporter 37 | 37
tight junction 36 | 36
nucleotidyltransferase 33 | 33
aminoacyl-tRNA synthetase 28 | 28
phosphodiesterase 28 | 28
deaminase 27 | 27
extracellular matrix linker pr... 26 | 26
glycosidase 24 | 24
peroxidase 24 | 24
transaminase 24 | 24
HMG box transcription factor 22 | 22
cyclase 22 | 22
decarboxylase 21 | 21
gap junction 21 | 21
chaperonin 19 | 19
epimerase/racemase 19 | 19
Hsp70 family chaperone 18 | 18
apolipoprotein 16 | 16
annexin 14 | 14
immunoglobulin superfamily cel... 14 | 14
basic leucine zipper transcrip... 12 | 12
deacetylase 12 | 12
glucosidase 12 | 12
mutase 12 | 12
Hsp90 family chaperone 11 | 11
phosphorylase 11 | 11
hydroxylase 8 | 8
viral coat protein 8 | 8
amylase 6 | 6
galactosidase 6 | 6
immunoglobulin 5 | 5
pyrophosphatase 5 | 5
myelin protein 4 | 4
calsequestrin 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.17375 14.4 26
Ecto-ADP-ribosyltransferase 3 ART3 Tbio Enzyme -1.29743 20.5 266
Tetratricopeptide repeat protein 34 TTC34 Tdark Non-IDG 0.44 0.27 48
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q PIGQ Tdark Enzyme -1.37033 23.2 36
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B3GNT5 Tbio Enzyme -0.90744 8.69 77
Tetratricopeptide repeat protein 7B TTC7B Tbio Non-IDG -0.28631 2.17 15
Tumor suppressor candidate 3 TUSC3 Tbio Non-IDG -1.90417 72.8 109
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase GCNT1 Tchem Enzyme -1.96073 91.9 156
UDP-glucuronosyltransferase 2B28 UGT2B28 Tdark Enzyme -0.77637 6.83 37
Glucoside xylosyltransferase 2 GXYLT2 Tdark Enzyme -0.00412 0.54 48