Development Level

Tbio 88 | 11,178
Tdark 22 | 6,569
Tchem 9 | 1,885
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
decreased circulating insulin ... 2 | 76
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
long tibia 2 | 25
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal skin morphology 1 | 50
abnormal tail movements 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
enlarged lung 1 | 2
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased CD8-positive, alpha-... 1 | 1
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glycerol... 1 | 9
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small adrenal glands 1 | 16
small kidney 1 | 16
small spleen 1 | 19
thick skin 1 | 4

Disease

Carcinoma 84 | 11,192
ovarian cancer 63 | 8,297
osteosarcoma 59 | 7,766
glioblastoma 47 | 5,635
psoriasis 42 | 6,514
atypical teratoid / rhabdoid tumor 36 | 4,971
medulloblastoma, large-cell 36 | 6,086
ependymoma 34 | 4,559
lung cancer 33 | 4,607
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,902
lung adenocarcinoma 30 | 2,627
Astrocytoma, Pilocytic 28 | 3,006
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,204
adult high grade glioma 25 | 3,701
Breast cancer 23 | 3,469
group 3 medulloblastoma 23 | 4,002
pituitary cancer 21 | 1,915
malignant mesothelioma 19 | 3,135
pancreatic cancer 19 | 2,322
Autosomal recessive predisposition 18 | 1,407
primitive neuroectodermal tumor 18 | 2,957
non-small cell lung cancer 17 | 2,799
Multiple myeloma 16 | 1,296
group 4 medulloblastoma 16 | 1,806
interstitial cystitis 16 | 2,237
invasive ductal carcinoma 16 | 2,867
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,911
subependymal giant cell astrocytoma 16 | 2,230
Congenital disorder of glycosylation 15 | 54
Kidney cancer 15 | 2,548
astrocytic glioma 15 | 2,530
lung carcinoma 15 | 2,755
oligodendroglioma 15 | 2,768
cystic fibrosis 14 | 1,629
active Crohn's disease 13 | 882
tuberculosis 13 | 1,963
breast carcinoma 12 | 1,589
astrocytoma 11 | 1,113
colon cancer 11 | 1,428
juvenile dermatomyositis 11 | 1,147
Muscle hypotonia 10 | 562
ductal carcinoma in situ 10 | 1,686
gastric carcinoma 10 | 781
Cancer 9 | 2,388
Cognitive delay 9 | 596
Global developmental delay 9 | 596
Mental and motor retardation 9 | 596
Pick disease 9 | 1,856
Rheumatoid arthritis 9 | 1,156
Seizures 9 | 584
non primary Sjogren syndrome sicca 9 | 861
pediatric high grade glioma 9 | 1,035
ulcerative colitis 9 | 1,765
Epilepsy 8 | 775
Failure to gain weight 8 | 359
Liver Cirrhosis, Experimental 8 | 733
Pediatric failure to thrive 8 | 359
Short stature 8 | 514
diabetes mellitus 8 | 1,683
nasopharyngeal carcinoma 8 | 1,024
spina bifida 8 | 1,053
Atopic dermatitis 7 | 915
Intellectual disability 7 | 998
active ulcerative colitis 7 | 736
acute quadriplegic myopathy 7 | 1,133
cutaneous lupus erythematosus 7 | 1,016
esophageal adenocarcinoma 7 | 696
Exostosis 6 | 15
Small head 6 | 366
Strabismus 6 | 265
Waldenstrons macroglobulinemia 6 | 742
Walker-Warburg syndrome 6 | 20
fibroadenoma 6 | 538
medulloblastoma 6 | 702
Congenital muscular dystrophy 5 | 29
Dull intelligence 5 | 634
Isoelectric focusing of serum transferrin consistent with CDG type I 5 | 10
Low intelligence 5 | 634
Mental Retardation 5 | 634
Mental deficiency 5 | 634
Myopathy 5 | 185
Poor school performance 5 | 634
Prostatic Neoplasms 5 | 472
Schizophrenia 5 | 1,136
acute myeloid leukemia 5 | 760
adrenocortical carcinoma 5 | 1,385
atypical teratoid/rhabdoid tumor 5 | 349
primary Sjogren syndrome 5 | 710
primary pancreatic ductal adenocarcinoma 5 | 1,071
Acquired scoliosis 4 | 274
Alzheimer's disease 4 | 640
Concave bridge of nose 4 | 191
Curvature of spine 4 | 275
Depressed nasal bridge 4 | 191
Depressed nasal root/bridge 4 | 191
Elevated creatine kinase 4 | 110
aldosterone-producing adenoma 4 | 646
dermatomyositis 4 | 941
pancreatic carcinoma 4 | 555

Tissue

Endocrine System 119 | 18,159
Blood and immune system 116 | 16,909
Digestive Tract 116 | 17,369
Female tissues 116 | 17,400
Nervous System 115 | 16,725
Skin and soft tissues 115 | 17,230
Liver and Pancreas 114 | 16,750
Male tissues 114 | 17,142
Urinary Tract 114 | 16,678
Respiratory system 113 | 16,393
Cardiovascular System 103 | 15,192

Target Family

Enzyme 114 | 4,145
Non-IDG 7 | 12,091

PANTHER Protein Class (1)

glycosyltransferase 121 | 121
RNA binding protein 476 | 476
kinase 357 | 357
DNA binding protein 338 | 338
protease 224 | 224
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
protease inhibitor 196 | 196
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
transcription cofactor 96 | 96
helix-turn-helix transcription... 87 | 87
ubiquitin-protein ligase 83 | 83
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
zinc finger transcription fact... 50 | 50
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
basic helix-loop-helix transcr... 42 | 42
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
nucleotidyltransferase 20 | 20
transaminase 18 | 18
metalloprotease 16 | 16
carbohydrate transporter 15 | 15
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
basic leucine zipper transcrip... 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
glycosidase 11 | 11
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
phosphodiesterase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
HMG box transcription factor 1 | 1
aldolase 1 | 1

This is where graphics are reside..