Development Level

Tbio 16 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
edema 1 | 59
enlarged spleen 1 | 41
hydrometra 1 | 53
increased or absent threshold ... 1 | 101
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 12 | 11,493
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Erythrokeratodermia variabilis 8 | 10
ovarian cancer 8 | 8,520
Oculodentodigital dysplasia 7 | 14
adult high grade glioma 7 | 3,801
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Cataract 5 | 297
Clouston syndrome 5 | 9
Nonsyndromic deafness 5 | 142
Palmoplantar keratosis 5 | 74
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Alopecia 4 | 115
Autosomal recessive predisposition 4 | 1,442
Deafness, autosomal recessive 1A 4 | 4
Erythema 4 | 58
Flushing 4 | 60
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Lens Opacities 4 | 231
Sensorineural hearing loss 4 | 106
Small head 4 | 374
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Autistic Disorder 3 | 364
Bart-Pumphrey syndrome 3 | 4
Cancer 3 | 2,499
Charcot-Marie-Tooth disease 3 | 62
Conductive hearing loss 3 | 123
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 3 | 3
Deafness 3 | 198
Dull intelligence 3 | 645
Dystrophic fingernails 3 | 18
Enlarged vestibular aqueduct 3 | 10
Epilepsy 3 | 792
Fine hair 3 | 42
Frontal bossing 3 | 157
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Low Vision 3 | 174
Low intelligence 3 | 645
MEDNIK syndrome 3 | 8
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Myopia 3 | 176
Nail dysplasia 3 | 52
Neuropathy 3 | 261
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Skin Neoplasms 3 | 69
Sparse eyelashes 3 | 31
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
Visual Impairment 3 | 174
X- linked recessive 3 | 110
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Abnormal blistering of the skin 2 | 54
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Blister of skin 2 | 54
Broad thumbs 2 | 28
Congenital deafness 2 | 185
Cortical white matter abnormalities seen on MRI 2 | 18
Dry skin 2 | 75
Dystrophia unguium 2 | 53
Enophthalmos 2 | 75
Hearing Loss, Partial 2 | 185
Leukoaraiosis 2 | 18
Peripheral Neuropathy 2 | 134
Photodysphoria 2 | 121
Photophobia 2 | 121
Sinoatrial node disease 2 | 5
Skin bulla 2 | 54
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Sunken eyes 2 | 63
Weight decreased 2 | 103
Xerosis 2 | 75
facioscapulohumeral dystrophy 2 | 288
hearing impairment 2 | 199

Tissue

Endocrine System 20 | 18,159
Urinary Tract 19 | 16,678
Female tissues 18 | 17,400
Digestive Tract 17 | 17,369
Liver and Pancreas 17 | 16,750
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 14 | 16,393
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 21 | 12,091

PANTHER Protein Class (1)

gap junction 21 | 21
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Putative gap junction epsilon-1 protein GJE1 Tdark Non-IDG -0.53712 3.69 16
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212
Gap junction alpha-10 protein GJA10 Tdark Non-IDG 0.15 0.90 51
Gap junction beta-1 protein GJB1 Tbio Non-IDG -2.93115 861.6 295