Development Level

Tbio 28 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

decreased body length 2 | 101
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased blood urea nitrogen ... 2 | 48
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal incisor morphology 1 | 4
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38

Disease

Carcinoma 26 | 11,493
ovarian cancer 18 | 8,520
psoriasis 16 | 6,694
invasive ductal carcinoma 14 | 2,951
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
ependymoma 13 | 4,679
glioblastoma 13 | 5,792
pancreatic cancer 13 | 2,398
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung carcinoma 12 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
primary pancreatic ductal adenocarcinoma 11 | 1,109
breast carcinoma 10 | 1,638
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
osteosarcoma 10 | 7,950
Kidney cancer 9 | 2,613
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
group 3 medulloblastoma 8 | 4,104
adult high grade glioma 7 | 3,801
gastric carcinoma 7 | 807
medulloblastoma, large-cell 7 | 6,241
Atopic dermatitis 6 | 952
interstitial cystitis 6 | 2,312
Autosomal recessive predisposition 5 | 1,442
Hypoplastic mandible condyle 5 | 275
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Myopia 5 | 176
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
fibroadenoma 5 | 559
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Age related macular degeneration 4 | 72
Arachnodactyly 4 | 49
Brachydactyly 4 | 156
Cancer 4 | 2,499
Cutis Laxa 4 | 39
Duchenne muscular dystrophy 4 | 601
Generalized elastolysis 4 | 24
Hanging skin 4 | 24
Melanoma 4 | 711
Mitral valve insufficiency 4 | 49
Orbital separation excessive 4 | 244
Osteoarthritis 4 | 184
Pulmonary emphysema 4 | 48
Short stature 4 | 531
Skin cancer 4 | 469
Weill-Marchesani syndrome 4 | 14
aldosterone-producing adenoma 4 | 665
colon cancer 4 | 1,478
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Aortic aneurysm 3 | 38
Bladder Diverticulum 3 | 15
Bulbous nasal tip 3 | 48
Bulbous nose 3 | 48
Byzanthine arch palate 3 | 194
Cataract 3 | 297
Chubby cheeks 3 | 50
Colorectal Neoplasms 3 | 243
Congestive heart failure 3 | 113
Decreased joint mobility 3 | 53
Down syndrome 3 | 499
Ectopia Lentis 3 | 17
Full cheeks 3 | 50
Hernia, Inguinal 3 | 89
Hyperplasia of cheeks 3 | 50
Hypertrophy of cheeks 3 | 50
Hypotrophic malar bone 3 | 129
Joint hyperflexibility 3 | 78
Joint stiffness 3 | 84
Liver cancer 3 | 604
Long philtrum 3 | 137
Macular degeneration 3 | 65
Malar flattening 3 | 129
Mitral Valve Prolapse Syndrome 3 | 39
Mitral regurgitation, mild 3 | 32
Pectus excavatum 3 | 100
Platyspondyly 3 | 56
Potato nose 3 | 48
Puffy cheeks 3 | 50
Pulmonary hypertension 3 | 85
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
group 4 medulloblastoma 3 | 1,855
interstitial lung disease 3 | 298
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Female tissues 31 | 17,400
Digestive Tract 30 | 17,369
Liver and Pancreas 30 | 16,750
Skin and soft tissues 30 | 17,230
Blood and immune system 29 | 16,909
Endocrine System 29 | 18,159
Male tissues 29 | 17,142
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 31 | 12,091

PANTHER Protein Class (1)

extracellular matrix structura... 31 | 31
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Fibulin-5 FBLN5 Tbio Non-IDG -2.32385 217.1 297
Adipolin C1QTNF12 Tbio Non-IDG -0.85014 9.69 30
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Erythroferrone ERFE Tdark Non-IDG -1.49901 30.9 3
Fibrillin-3 FBN3 Tbio Non-IDG -1.23024 15.7 16
Collagen alpha-1(XXVII) chain COL27A1 Tbio Non-IDG -1.91497 69.8 17