Development Level

Tbio 77 | 11,445
Tclin 13 | 613
Tdark 6 | 6,588
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased vertical activity 4 | 208
enlarged heart 4 | 210
abnormal heart morphology 3 | 162
decreased circulating insulin ... 3 | 76
preweaning lethality, complete... 3 | 979
abnormal brain morphology 2 | 13
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased heart weight 2 | 27
decreased total body fat amoun... 2 | 207
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal neural tube morpholog... 1 | 12
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged liver 1 | 2
enlarged spleen 1 | 41
hydroencephaly 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
pale yolk sac 1 | 25
small seminal vesicle 1 | 10
tremors 1 | 39
trunk curl 1 | 16

Disease

psoriasis 69 | 6,694
Cancer 47 | 2,499
lung cancer 46 | 4,740
interstitial cystitis 44 | 2,312
tuberculosis 42 | 2,010
ovarian cancer 41 | 8,520
Carcinoma 37 | 11,493
malignant mesothelioma 37 | 3,232
osteosarcoma 37 | 7,950
lung carcinoma 34 | 2,843
ulcerative colitis 33 | 1,819
glioblastoma 32 | 5,792
non-small cell lung cancer 31 | 2,890
Asthma 30 | 385
lung adenocarcinoma 30 | 2,716
adult high grade glioma 29 | 3,801
medulloblastoma, large-cell 27 | 6,241
Breast cancer 24 | 3,578
Multiple Sclerosis 24 | 540
Rheumatoid arthritis 24 | 1,191
invasive ductal carcinoma 23 | 2,951
cystic fibrosis 22 | 1,696
ependymoma 22 | 4,679
Hypersensitivity 21 | 63
cutaneous lupus erythematosus 21 | 1,057
Pneumonia 20 | 174
atypical teratoid / rhabdoid tumor 20 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
pancreatic cancer 20 | 2,398
Astrocytoma, Pilocytic 19 | 3,081
colon cancer 19 | 1,478
diabetes mellitus 19 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Arthritis 18 | 290
Atopic dermatitis 18 | 952
Lung disease 18 | 142
Hypersensitivity reaction type II disease 17 | 253
breast carcinoma 17 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
nasopharyngeal carcinoma 17 | 1,058
active Crohn's disease 16 | 922
Atherosclerosis 15 | 291
Dermatitis 15 | 157
Inflammatory bowel disease 15 | 151
pituitary cancer 15 | 1,972
Influenza 14 | 142
Liver Cirrhosis, Experimental 14 | 769
Allergic hypersensitivity disease 13 | 126
Hypereosinophilic syndrome 13 | 71
Schizophrenia 13 | 1,160
active ulcerative colitis 13 | 764
Arthritis, Rheumatoid 12 | 174
Mesothelioma, Malignant 12 | 105
ductal carcinoma in situ 12 | 1,745
hepatocellular carcinoma 12 | 547
periodontitis 12 | 293
group 3 medulloblastoma 11 | 4,104
juvenile dermatomyositis 11 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
sarcoidosis 11 | 370
Inflammation 10 | 120
Pulmonary Fibrosis 10 | 106
head and neck cancer 10 | 271
mucosa-associated lymphoid tissue lymphoma 10 | 484
primary Sjogren syndrome 10 | 735
Allergic rhinitis 9 | 94
Breast Neoplasms 9 | 445
Coronary artery disease 9 | 268
Crohn's disease 9 | 321
Endometriosis 9 | 540
Hypertension 9 | 396
Kidney disease 9 | 430
Malaria 9 | 160
Mammary Neoplasms 9 | 425
Myocardial Ischemia 9 | 169
Vascular disease 9 | 319
esophageal adenocarcinoma 9 | 737
subependymal giant cell astrocytoma 9 | 2,287
Common cold 8 | 67
Glomerulonephritis 8 | 46
Human immunodeficiency virus infectious disease 8 | 138
Pick disease 8 | 1,894
acute myeloid leukemia 8 | 783
gastric cancer 8 | 459
gastric carcinoma 8 | 807
group 4 medulloblastoma 8 | 1,855
non primary Sjogren syndrome sicca 8 | 891
non-small cell lung carcinoma 8 | 317
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Abortion, Spontaneous 7 | 109
Autosomal recessive predisposition 7 | 1,442
Brain Ischemia 7 | 110
Cerebrovascular disease 7 | 238
Obesity 7 | 678
Prostatic Neoplasms 7 | 495
Reperfusion Injury 7 | 86
Spontaneous abortion 7 | 113
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
spina bifida 7 | 1,074

Tissue

Blood and immune system 99 | 16,909
Digestive Tract 99 | 17,369
Endocrine System 99 | 18,159
Liver and Pancreas 98 | 16,750
Female tissues 97 | 17,400
Respiratory system 96 | 16,393
Urinary Tract 96 | 16,678
Male tissues 95 | 17,142
Skin and soft tissues 95 | 17,230
Nervous System 84 | 16,725
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 96 | 12,091
Enzyme 5 | 4,145

PANTHER Protein Class (1)

cytokine 101 | 101
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
Cytokine receptor-like factor 2 CRLF2 Tbio Non-IDG -1.91113 78.7 393
C-C motif chemokine 16 CCL16 Tbio Non-IDG -2.43196 263.6 267
C-C motif chemokine 4-like CCL4L2 Tbio Non-IDG -2.65884 375.0 67
Platelet basic protein PPBP Tbio Non-IDG -3.18788 1559.1 453