Development Level

Tbio 4 | 11,445
Tclin 3 | 613

IMPC Phenotype

prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 5 | 11,493
lung carcinoma 4 | 2,843
Autosomal recessive predisposition 3 | 1,442
Kidney cancer 3 | 2,613
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Cone dystrophy 2 | 71
Hypertension 2 | 396
Leber congenital amaurosis 2 | 69
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
ulcerative colitis 2 | 1,819
Abnormal color vision 1 | 31
Acromesomelic dysplasia 1 | 10
Albuminuria 1 | 21
Amaurosis congenita of Leber, type 1 1 | 1
Arts syndrome 1 | 26
Beaked vertebral bodies 1 | 9
Brachyonychia 1 | 6
Bradyopsia 1 | 10
Broad hallux 1 | 29
Bullet vertebral body 1 | 17
Cardiomegaly 1 | 116
Central areolar choroidal sclerosis 1 | 2
Cerebellar vermis aplasia or hypoplasia 1 | 12
Cerebellar vermis aplasia/ hypoplasia 1 | 12
Childhood onset 1 | 38
Choroidal sclerosis 1 | 8
Chromosome 13q14 deletion syndrome 1 | 6
Chronic idiopathic constipation 1 | 3
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Colorectal cancer 1 | 25
Cone-Rod Dystrophy 5 1 | 2
Cone-Rod Dystrophy 6 1 | 1
Cone-shaped epiphyses of phalanges 1 | 15
Cone/cone-rod dystrophy 1 | 20
Congenital hypoplasia of radius 1 | 23
DIARRHEA 6 1 | 2
Decompensated cardiac failure 1 | 9
Decreased amplitudes on flash visual electroretinogram 1 | 13
Distal intestinal obstruction syndrome 1 | 2
Eye poking 1 | 2
Fibrosis 1 | 44
Fundus atrophy 1 | 2
Fundus dystrophy 1 | 83
Gastroesophageal junction adenocarcinoma 1 | 1
Generalized osteopenia 1 | 99
Hemiplegia and hemiparesis 1 | 38
Human immunodeficiency virus infectious disease 1 | 138
Hyperkyphosis 1 | 111
Hyperthreoninuria 1 | 1
Hypoplastic toes 1 | 29
Irritable bowel syndrome 1 | 60
Irritable bowel syndrome characterized by constipation 1 | 3
Joint laxity 1 | 54
Joint stiffness 1 | 84
Kyphosis deformity of spine 1 | 114
Leber congenital amaurosis 1 1 | 6
Limited elbow extension 1 | 19
Long hallux 1 | 5
Lordosis 1 | 54
Loss of peripheral vision 1 | 5
Macroglobulinemia 1 | 18
Meconium ileus 1 | 3
Meconium ileus on ultrasonography 1 | 2
Microcolon 1 | 4
Microcolon on contrast enema 1 | 4
Optic disc abnormalities 1 | 12
Osteopenia 1 | 99
Ovoid vertebral bodies 1 | 17
Pain 1 | 103
Paroxysmal nocturnal hemoglobinuria 1 | 10
Partial central choroid dystrophy 1 | 11
Primary immunodeficiency disease 1 | 54
Radial ray hypoplasia 1 | 23
Reduced visual acuity 1 | 63
Retinal cone dystrophy 2 1 | 1
Retinopathy of prematurity 1 | 22
Severe visual impairment 1 | 16
Short metatarsal 1 | 21
Short phalanx of finger 1 | 32
Short stature, disproportionate 1 | 9
Short stature, severe disproportionate 1 | 9
Splayed metaphyses 1 | 19
Sprengel deformity 1 | 16
THREONINEMIA 1 | 1
Tall stature 1 | 34
Tunnel visual field constriction 1 | 5
Vertebral wedging 1 | 4
Wedging of vertebra 1 | 9
cone-rod dystrophy 1 | 59
non-syndromic X-linked intellectual disability 1 | 20

Tissue

Endocrine System 7 | 18,159
Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Female tissues 6 | 17,400
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Cardiovascular System 5 | 15,192
Liver and Pancreas 5 | 16,750
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Urinary Tract 5 | 16,678

Target Family

Kinase 5 | 634
Enzyme 2 | 4,145

PANTHER Protein Class (1)

cyclase 7 | 7
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.00236 7.60 84
Atrial natriuretic peptide receptor 1 NPR1 Tclin Kinase -2.61776 410.0 214
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 BST1 Tbio Enzyme -1.86410 73.3 284
Atrial natriuretic peptide receptor 2 NPR2 Tbio Kinase -2.11421 138.1 180