Development Level

Tbio 82 | 11,651
Tdark 25 | 6,593
Tchem 12 | 1,388
Tclin 8 | 612

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased prepulse inhibition 2 | 82
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased erythrocyte cell num... 1 | 62
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
limb grasping 1 | 41
small heart 1 | 10
small spleen 1 | 19

Disease

Carcinoma 97 | 11,493
osteosarcoma 60 | 7,950
ovarian cancer 59 | 8,520
medulloblastoma, large-cell 52 | 6,241
glioblastoma 39 | 5,792
psoriasis 38 | 6,694
atypical teratoid / rhabdoid tumor 37 | 5,112
group 3 medulloblastoma 31 | 4,104
ependymoma 30 | 4,679
lung cancer 28 | 4,740
malignant mesothelioma 28 | 3,232
lung carcinoma 25 | 2,843
oligodendroglioma 25 | 2,850
Kidney cancer 24 | 2,613
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
primitive neuroectodermal tumor 22 | 3,035
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Astrocytoma, Pilocytic 18 | 3,081
Schizophrenia 18 | 1,160
Epilepsy 17 | 792
cystic fibrosis 17 | 1,696
non-small cell lung cancer 17 | 2,890
Autosomal recessive predisposition 16 | 1,442
Pick disease 16 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
invasive ductal carcinoma 16 | 2,951
lung adenocarcinoma 15 | 2,716
pituitary cancer 15 | 1,972
Breast cancer 14 | 3,578
subependymal giant cell astrocytoma 14 | 2,287
Parkinson's disease 13 | 392
Bipolar Disorder 12 | 666
Multiple myeloma 12 | 1,332
interstitial cystitis 12 | 2,312
pancreatic cancer 12 | 2,398
Alzheimer's disease 11 | 658
Rheumatoid arthritis 11 | 1,191
non primary Sjogren syndrome sicca 11 | 891
tuberculosis 11 | 2,010
Intellectual disability 10 | 1,016
Seizures 10 | 596
active Crohn's disease 10 | 922
active ulcerative colitis 10 | 764
ductal carcinoma in situ 10 | 1,745
ulcerative colitis 10 | 1,819
Metabolic acidosis 9 | 90
astrocytoma 9 | 1,146
diabetes mellitus 9 | 1,728
group 4 medulloblastoma 9 | 1,855
pediatric high grade glioma 9 | 1,064
spina bifida 9 | 1,074
Alcoholic Intoxication, Chronic 8 | 289
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
adrenocortical carcinoma 8 | 1,428
colon cancer 8 | 1,478
mucosa-associated lymphoid tissue lymphoma 8 | 484
Failure to gain weight 7 | 365
Major Depressive Disorder 7 | 301
Melanoma 7 | 711
Pediatric failure to thrive 7 | 365
nephrosclerosis 7 | 333
Amyotrophic lateral sclerosis 6 | 451
Anemia 6 | 365
Cancer 6 | 2,499
Depressive disorder 6 | 409
Glaucoma 6 | 239
Liver Cirrhosis, Experimental 6 | 769
Mental Depression 6 | 333
Muscle hypotonia 6 | 571
Toxic encephalopathy 6 | 141
Unipolar Depression 6 | 250
Waldenstrons macroglobulinemia 6 | 765
nasopharyngeal carcinoma 6 | 1,058
primary pancreatic ductal adenocarcinoma 6 | 1,109
Attention deficit hyperactivity disorder 5 | 278
Cerebellar Ataxia 5 | 304
Growth delay 5 | 114
Growth failure 5 | 114
Growth retardation 5 | 115
Hepatomegaly 5 | 285
Hypertension 5 | 396
Infantile onset 5 | 238
Poor growth 5 | 114
Renal tubular acidosis 5 | 24
Skin cancer 5 | 469
Very poor growth 5 | 114
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
medulloblastoma 5 | 720
primary Sjogren syndrome 5 | 735
gastric carcinoma 4 | 807
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 121 | 18,159
Digestive Tract 118 | 17,369
Male tissues 118 | 17,142
Urinary Tract 117 | 16,678
Skin and soft tissues 115 | 17,230
Female tissues 114 | 17,400
Liver and Pancreas 114 | 16,750
Blood and immune system 113 | 16,909
Nervous System 113 | 16,725
Respiratory system 106 | 16,393
Cardiovascular System 93 | 15,192

Target Family

Transporter 83 | 473
Enzyme 26 | 4,145
Non-IDG 18 | 12,091

PANTHER Protein Class (1)

cation transporter 127 | 127
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
V-type proton ATPase 16 kDa proteolipid subunit ATP6V0C Tbio Enzyme -1.87899 78.9 72
Solute carrier family 13 member 5 SLC13A5 Tchem Transporter -1.70063 50.0 86
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -2.00898 110.3 57
Sideroflexin-3 SFXN3 Tdark Non-IDG -0.50060 3.38 107
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.40105 25.1 63