Development Level

Tbio 7 | 11,651

IMPC Phenotype

abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased cardiac muscle contr... 1 | 11
dilated heart left ventricle 1 | 11
increased heart weight 1 | 62
narrow eye opening 1 | 12

Disease

Breast cancer 7 | 3,578
Carcinoma 7 | 11,493
Melanoma 5 | 711
Ritter's disease 5 | 10
Skin cancer 5 | 469
Dermatitis 4 | 157
esophageal adenocarcinoma 4 | 737
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
Arrhythmogenic right ventricular cardiomyopathy 3 | 30
Hypotrichosis 3 | 47
Kidney cancer 3 | 2,613
Pemphigus 3 | 23
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
spina bifida 3 | 1,074
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Bullous pemphigoid 2 | 18
Cardiomyopathy 2 | 116
Cardiomyopathy, right ventricular 2 | 7
Dilated cardiomyopathy 2 | 56
Netherton syndrome 2 | 15
Palmoplantar keratosis 2 | 74
Palpitations 2 | 18
Peeling skin syndrome 2 | 17
Sudden Cardiac Death 2 | 29
X-linked dystonia-parkinsonism 2 | 9
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
periodontitis 2 | 293
ulcerative colitis 2 | 1,819
urothelial carcinoma 2 | 318
Afro-textured hair 1 | 13
Atrioventricular block 1 | 35
Breast Neoplasms 1 | 445
Cancer 1 | 2,499
Cardiomyopathy, Dilated 1 | 83
Chemical and Drug Induced Liver Injury 1 | 195
Dyspnea 1 | 76
Eosinophilic esophagitis 1 | 16
Epidermolysis bullosa 1 | 21
Epidermolysis bullosa acquisita 1 | 10
Esophagitis 1 | 35
Exfoliative dermatitis 1 | 24
Familial isolated dilated cardiomyopathy 1 | 41
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hair shaft abnormalities 1 | 30
Hypersensitivity 1 | 63
Hypopituitarism 1 | 40
Hypotrichosis 6 1 | 4
Hypotrichosis simplex 1 | 7
Ichthyosis vulgaris 1 | 11
Impetigo 1 | 8
Kinky hair texture 1 | 13
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Lichen planus 1 | 16
Lipid metabolism disorder 1 | 114
Lymphoid leukemia 1 | 160
Mammary Neoplasms 1 | 425
Metabolic Diseases 1 | 10
Monilethrix 1 | 18
Multiple Sclerosis 1 | 540
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Nappy hair texture 1 | 13
Noonan syndrome 1 | 34
Parkinson's disease 1 | 392
Poor growth 1 | 114
Premature ventricular contractions 1 | 6
Recurrent respiratory infections 1 | 141
Recurrent skin infections 1 | 21
Right bundle branch block 1 | 17
Spindle cell hemangioma 1 | 16
Squamous cell carcinoma 1 | 129
Syncope 1 | 22
Tachycardia, Ventricular 1 | 22
Type 2 diabetes mellitus 1 | 272
Ventricular arrhythmia 1 | 27
Very poor growth 1 | 114
Wooly hair 1 | 17
facioscapulohumeral dystrophy 1 | 288
hair abnormalities (non-specific) 1 | 30
lung adenocarcinoma 1 | 2,716
nasopharyngeal carcinoma 1 | 1,058
pulmonary arterial hypertension 1 | 76
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Skin and soft tissues 7 | 17,230
Blood and immune system 6 | 16,909
Female tissues 6 | 17,400
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Cardiovascular System 5 | 15,192
Urinary Tract 5 | 16,678
Liver and Pancreas 4 | 16,750
Respiratory system 4 | 16,393

Target Family

Non-IDG 7 | 12,091

PANTHER Protein Class (1)

cadherin 7 | 7
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmoglein-3 DSG3 Tbio Non-IDG -2.57795 402.0 381
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
Desmocollin-1 DSC1 Tbio Non-IDG -1.46161 25.1 146
Desmoglein-4 DSG4 Tbio Non-IDG -2.32175 214.8 78
Desmocollin-3 DSC3 Tbio Non-IDG -2.47398 295.5 177
Desmoglein-2 DSG2 Tbio Non-IDG -2.03972 117.7 407