Development Level

Tbio 51 | 11,651
Tdark 6 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

increased bone mineral density 3 | 72
preweaning lethality, incomple... 3 | 499
abnormal retina morphology 2 | 71
abnormal testis morphology 2 | 43
decreased vertical activity 2 | 208
increased mean corpuscular hem... 2 | 96
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal ovary morphology 1 | 7
abnormal seminal vesicle morph... 1 | 114
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58
small uterus 1 | 3

Disease

Carcinoma 34 | 11,493
medulloblastoma, large-cell 29 | 6,241
ovarian cancer 26 | 8,520
psoriasis 26 | 6,694
Cancer 24 | 2,499
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 18 | 5,112
lung cancer 18 | 4,740
malignant mesothelioma 17 | 3,232
Breast cancer 16 | 3,578
ependymoma 14 | 4,679
invasive ductal carcinoma 14 | 2,951
oligodendroglioma 14 | 2,850
group 3 medulloblastoma 13 | 4,104
astrocytic glioma 12 | 2,597
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 11 | 3,035
acute quadriplegic myopathy 10 | 1,158
adult high grade glioma 10 | 3,801
pancreatic cancer 10 | 2,398
tuberculosis 10 | 2,010
breast carcinoma 9 | 1,638
cystic fibrosis 9 | 1,696
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
Astrocytoma, Pilocytic 8 | 3,081
Bipolar Disorder 8 | 666
group 4 medulloblastoma 8 | 1,855
lung carcinoma 8 | 2,843
pediatric high grade glioma 8 | 1,064
Breast Neoplasms 7 | 445
Cleft Palate 7 | 271
Kidney cancer 7 | 2,613
Mammary Neoplasms 7 | 425
adrenocortical carcinoma 7 | 1,428
diabetes mellitus 7 | 1,728
gastric carcinoma 7 | 807
Schizophrenia 6 | 1,160
Strabismus 6 | 270
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
medulloblastoma 6 | 720
Prostatic Neoplasms 5 | 495
acute myeloid leukemia 5 | 783
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Chronic Lymphocytic Leukemia 4 | 262
Intellectual disability 4 | 1,016
Low set ears 4 | 181
Lung Neoplasms 4 | 232
Multiple Sclerosis 4 | 540
Myopathy 4 | 185
Obesity 4 | 678
Precursor Cell Lymphoblastic Leukemia-Lymphoma 4 | 49
Skeletal muscle neoplasm 4 | 8
atypical teratoid/rhabdoid tumor 4 | 357
cutaneous lupus erythematosus 4 | 1,057
Atopic dermatitis 3 | 952
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Colonic Neoplasms 3 | 142
Deafness 3 | 198
Epilepsy 3 | 792
Gastroesophageal reflux disease 3 | 110
Hearing Loss, Partial 3 | 185
Heart disease 3 | 306
Heartburn 3 | 78
Liver neoplasms 3 | 130
Mood Disorders 3 | 184
Neoplasm Invasiveness 3 | 161
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Pick disease 3 | 1,894
Posteriorly rotated ear 3 | 61
Psychotic Disorders 3 | 151
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
Wide skull shape 3 | 88
active ulcerative colitis 3 | 764
acute lymphocytic leukemia 3 | 33
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
nephrosclerosis 3 | 333
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group A ependymoma 3 | 468
urothelial carcinoma 3 | 318

Tissue

Skin and soft tissues 55 | 17,230
Endocrine System 54 | 18,159
Male tissues 54 | 17,142
Digestive Tract 53 | 17,369
Female tissues 52 | 17,400
Blood and immune system 51 | 16,909
Nervous System 49 | 16,725
Urinary Tract 49 | 16,678
Respiratory system 47 | 16,393
Liver and Pancreas 46 | 16,750
Cardiovascular System 40 | 15,192

Target Family

Transcription Factor 51 | 1,400
Non-IDG 9 | 12,091

PANTHER Protein Class (1)

basic helix-loop-helix transcr... 60 | 60
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor HES-1 HES1 Tbio Transcription Factor -1.77409 55.5 444
Neuronal PAS domain-containing protein 1 NPAS1 Tbio Transcription Factor -0.85546 7.62 136
Transcription factor HES-4 HES4 Tbio Transcription Factor -0.96102 8.66 85
Endothelial PAS domain-containing protein 1 EPAS1 Tchem Non-IDG -2.29071 180.5 477
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.53687 261.2 474
Max dimerization protein 3 MXD3 Tbio Transcription Factor -2.04549 108.3 184
Aryl hydrocarbon receptor nuclear translocator-like protein 2 ARNTL2 Tbio Transcription Factor -2.09050 123.6 94
Protein max MAX Tbio Transcription Factor -2.14268 110.6 398
Hypoxia-inducible factor 3-alpha HIF3A Tbio Non-IDG -2.54233 341.8 249
Twist-related protein 2 TWIST2 Tbio Transcription Factor -2.17949 148.1 159