Development Level

Tbio 39 | 11,651
Tchem 13 | 1,388
Tdark 5 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
decreased bone mineral content 2 | 151
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating creatine... 1 | 4
decreased circulating lipase l... 1 | 3
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged heart 1 | 210
hyperactivity 1 | 148
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased lymphocyte cell numb... 1 | 32
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
premature death 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 40 | 11,493
osteosarcoma 29 | 7,950
ovarian cancer 28 | 8,520
psoriasis 23 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
medulloblastoma, large-cell 18 | 6,241
group 3 medulloblastoma 17 | 4,104
glioblastoma 15 | 5,792
ependymoma 13 | 4,679
lung cancer 13 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 12 | 2,951
Breast cancer 11 | 3,578
atypical teratoid / rhabdoid tumor 11 | 5,112
astrocytic glioma 10 | 2,597
lung carcinoma 10 | 2,843
oligodendroglioma 10 | 2,850
Astrocytoma, Pilocytic 9 | 3,081
Autosomal recessive predisposition 9 | 1,442
ductal carcinoma in situ 9 | 1,745
tuberculosis 9 | 2,010
Atopic dermatitis 8 | 952
adult high grade glioma 8 | 3,801
diabetes mellitus 8 | 1,728
pancreatic cancer 8 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,035
Obesity 7 | 678
interstitial cystitis 7 | 2,312
malignant mesothelioma 7 | 3,232
subependymal giant cell astrocytoma 7 | 2,287
Fatty liver disease 6 | 103
Ichthyosis 6 | 56
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
active Crohn's disease 6 | 922
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
non-small cell lung cancer 6 | 2,890
Anemia 5 | 365
Kidney cancer 5 | 2,613
Lipid metabolism disorder 5 | 114
Pick disease 5 | 1,894
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
group 4 medulloblastoma 5 | 1,855
progressive supranuclear palsy 5 | 676
Cerebellar Ataxia 4 | 304
Intellectual disability 4 | 1,016
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
lung adenocarcinoma 4 | 2,716
Alzheimer's disease 3 | 658
Autosomal dominant cerebellar ataxia 3 | 33
COENZYME Q10 DEFICIENCY, PRIMARY, 1 3 | 6
Coenzyme Q10 deficiency disease 3 | 8
Congenital ichthyosiform erythroderma 3 | 28
Dermatitis herpetiformis 3 | 12
Diarrhea 3 | 253
Dull intelligence 3 | 645
Dysarthria 3 | 192
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hypertrophic Cardiomyopathy 3 | 117
Ichthyoses 3 | 41
Leigh disease 3 | 100
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Motor delay 3 | 147
Multiple acyl-CoA dehydrogenase deficiency 3 | 25
No development of motor milestones 3 | 147
Nystagmus 3 | 317
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Retinitis Pigmentosa 3 | 226
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
gastric cancer 3 | 459
posterior fossa group B ependymoma 3 | 416
Atherosclerosis 2 | 291
Cancer 2 | 2,499
Duchenne muscular dystrophy 2 | 601
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
colon cancer 2 | 1,478
dermatomyositis 2 | 966
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074

Tissue

Female tissues 56 | 17,400
Skin and soft tissues 56 | 17,230
Male tissues 55 | 17,142
Blood and immune system 54 | 16,909
Digestive Tract 54 | 17,369
Endocrine System 54 | 18,159
Liver and Pancreas 52 | 16,750
Respiratory system 51 | 16,393
Nervous System 49 | 16,725
Urinary Tract 49 | 16,678
Cardiovascular System 45 | 15,192

Target Family

Enzyme 48 | 4,145
Non-IDG 11 | 12,091

PANTHER Protein Class (1)

acyltransferase 59 | 59
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Geranylgeranyl transferase type-2 subunit beta RABGGTB Tbio Enzyme -0.69980 4.51 47
Ancient ubiquitous protein 1 AUP1 Tbio Non-IDG -1.00442 12.6 142
Farnesyl pyrophosphate synthase FDPS Tclin Enzyme -2.94323 876.8 272
Protein-glutamine gamma-glutamyltransferase 5 TGM5 Tbio Enzyme -1.95470 84.9 129
Patatin-like phospholipase domain-containing protein 1 PNPLA1 Tbio Enzyme -1.33674 19.5 102
Erythrocyte membrane protein band 4.2 EPB42 Tbio Enzyme -0.95726 6.65 66
Glycerol-3-phosphate acyltransferase 4 GPAT4 Tbio Enzyme -1.61972 41.3 205
Patatin-like phospholipase domain-containing protein 4 PNPLA4 Tbio Enzyme -0.89406 6.90 80
Protein-glutamine gamma-glutamyltransferase E TGM3 Tchem Enzyme -2.69033 481.2 236