Development Level

Tbio 175 | 11,651
Tdark 44 | 6,593
Tchem 1 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 15 | 979
abnormal behavior 9 | 298
hyperactivity 8 | 148
preweaning lethality, incomple... 8 | 499
decreased body weight 6 | 161
embryonic lethality prior to t... 6 | 278
abnormal embryo size 4 | 220
decreased bone mineral density 4 | 126
decreased circulating glucose ... 4 | 126
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
abnormal bone mineralization 3 | 38
abnormal bone structure 3 | 187
abnormal sleep behavior 3 | 70
decreased circulating fructosa... 3 | 30
decreased circulating total pr... 3 | 49
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
increased circulating phosphat... 3 | 26
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
abnormal behavioral response t... 2 | 66
abnormal coat-hair pigmentatio... 2 | 64
abnormal locomotor activation 2 | 16
abnormal seminal vesicle morph... 2 | 114
abnormal vertebrae morphology 2 | 18
absent pinna reflex 2 | 23
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
abnormal coat- hair morphology 1 | 19
abnormal embryo turning 1 | 31
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58
stereotypic behavior 1 | 3
syndactyly 1 | 23
thin ventricular wall 1 | 24
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 145 | 11,493
ovarian cancer 109 | 8,520
glioblastoma 96 | 5,792
psoriasis 96 | 6,694
osteosarcoma 90 | 7,950
medulloblastoma, large-cell 82 | 6,241
atypical teratoid / rhabdoid tumor 78 | 5,112
ependymoma 71 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,989
lung cancer 62 | 4,740
adult high grade glioma 59 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
pancreatic cancer 58 | 2,398
primitive neuroectodermal tumor 58 | 3,035
Astrocytoma, Pilocytic 57 | 3,081
Breast cancer 55 | 3,578
group 3 medulloblastoma 53 | 4,104
malignant mesothelioma 53 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,291
invasive ductal carcinoma 52 | 2,951
non-small cell lung cancer 45 | 2,890
subependymal giant cell astrocytoma 45 | 2,287
oligodendroglioma 44 | 2,850
lung carcinoma 41 | 2,843
lung adenocarcinoma 36 | 2,716
primary pancreatic ductal adenocarcinoma 36 | 1,109
astrocytic glioma 34 | 2,597
interstitial cystitis 34 | 2,312
acute quadriplegic myopathy 33 | 1,158
breast carcinoma 33 | 1,638
colon cancer 32 | 1,478
spina bifida 32 | 1,074
ductal carcinoma in situ 31 | 1,745
diabetes mellitus 30 | 1,728
Pick disease 27 | 1,894
cystic fibrosis 27 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
pituitary cancer 26 | 1,972
ulcerative colitis 26 | 1,819
astrocytoma 25 | 1,146
tuberculosis 24 | 2,010
Duchenne muscular dystrophy 23 | 601
Kidney cancer 23 | 2,613
Rheumatoid arthritis 22 | 1,191
dermatomyositis 22 | 966
group 4 medulloblastoma 22 | 1,855
juvenile dermatomyositis 22 | 1,187
pediatric high grade glioma 22 | 1,064
Cancer 21 | 2,499
Liver Cirrhosis, Experimental 21 | 769
adrenocortical carcinoma 21 | 1,428
Autosomal recessive predisposition 17 | 1,442
gastric carcinoma 17 | 807
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 510
pancreatic carcinoma 16 | 562
Down syndrome 15 | 499
Multiple myeloma 15 | 1,332
esophageal adenocarcinoma 15 | 737
Alzheimer's disease 14 | 658
Schizophrenia 14 | 1,160
Waldenstrons macroglobulinemia 14 | 765
Amyotrophic lateral sclerosis 12 | 451
Atopic dermatitis 12 | 952
Bipolar Disorder 12 | 666
Hypertrophic Cardiomyopathy 12 | 117
active ulcerative colitis 12 | 764
gastric cancer 12 | 459
primary Sjogren syndrome 12 | 735
Cardiomyopathy 11 | 116
active Crohn's disease 11 | 922
aldosterone-producing adenoma 11 | 665
cutaneous lupus erythematosus 11 | 1,057
medulloblastoma 11 | 720
nasopharyngeal carcinoma 11 | 1,058
Becker muscular dystrophy 10 | 191
Cardiomyopathy, Dilated 10 | 83
Dilated cardiomyopathy 10 | 56
Nemaline myopathy 10 | 17
fibroadenoma 10 | 559
Intellectual disability 9 | 1,016
Nonsyndromic deafness 9 | 142
acute myeloid leukemia 9 | 783
chronic rhinosinusitis 9 | 512
hereditary spastic paraplegia 9 | 318
progressive supranuclear palsy 9 | 676
Acquired scoliosis 8 | 281
Coronary artery disease 8 | 268
Curvature of spine 8 | 282
Endometriosis 8 | 540
Liver cancer 8 | 604
Muscle hypotonia 8 | 571
Osteoporosis 8 | 363
Polycystic ovary syndrome 8 | 360
Wiskott-Aldrich syndrome 8 | 30
non primary Sjogren syndrome sicca 8 | 891
Epilepsy 7 | 792
Parkinson's disease 7 | 392
Substance-Related Disorders 7 | 115
mucosa-associated lymphoid tissue lymphoma 7 | 484
sonic hedgehog group medulloblastoma 7 | 467

Tissue

Endocrine System 215 | 18,159
Skin and soft tissues 207 | 17,230
Digestive Tract 205 | 17,369
Female tissues 205 | 17,400
Male tissues 204 | 17,142
Liver and Pancreas 203 | 16,750
Blood and immune system 201 | 16,909
Nervous System 201 | 16,725
Urinary Tract 200 | 16,678
Respiratory system 196 | 16,393
Cardiovascular System 191 | 15,192

Target Family

Non-IDG 202 | 12,091
Enzyme 11 | 4,145
Transcription Factor 8 | 1,400

PANTHER Protein Class (1)

actin family cytoskeletal prot... 221 | 221
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Troponin I, cardiac muscle TNNI3 Tbio Non-IDG -3.55281 3485.6 1706
Paxillin PXN Tbio Non-IDG -2.99437 902.9 1251
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Troponin T, cardiac muscle TNNT2 Tbio Non-IDG -3.19980 1554.3 829
Actin, aortic smooth muscle ACTA2 Tbio Non-IDG -2.25358 161.4 773
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Actin, alpha skeletal muscle ACTA1 Tbio Non-IDG -2.75790 541.5 749
Src substrate cortactin CTTN Tbio Non-IDG -2.62377 433.2 722
Cofilin-1 CFL1 Tbio Non-IDG -3.11815 1297.2 668