Development Level

Tbio 52 | 11,651
Tchem 11 | 1,388
Tdark 5 | 6,593

IMPC Phenotype

abnormal embryo size 4 | 220
preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
decreased vertical activity 3 | 208
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
increased total body fat amoun... 2 | 134
persistence of hyaloid vascula... 2 | 33
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cataract 1 | 92
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating creatine... 1 | 5
increased circulating phosphat... 1 | 26
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74

Disease

Carcinoma 49 | 11,493
ovarian cancer 41 | 8,520
psoriasis 29 | 6,694
osteosarcoma 28 | 7,950
medulloblastoma, large-cell 21 | 6,241
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
Breast cancer 15 | 3,578
malignant mesothelioma 15 | 3,232
Intellectual disability 14 | 1,016
group 3 medulloblastoma 14 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Cancer 13 | 2,499
Kidney cancer 13 | 2,613
Muscle hypotonia 13 | 571
adult high grade glioma 13 | 3,801
atypical teratoid / rhabdoid tumor 13 | 5,112
Autosomal recessive predisposition 12 | 1,442
Multiple myeloma 12 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Seizures 11 | 596
ulcerative colitis 11 | 1,819
Cognitive delay 10 | 608
Epilepsy 10 | 792
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
astrocytoma 10 | 1,146
ependymoma 10 | 4,679
invasive ductal carcinoma 10 | 2,951
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Breast Neoplasms 8 | 445
Small head 8 | 374
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
primitive neuroectodermal tumor 8 | 3,035
Congenital Epicanthus 7 | 177
Mammary Neoplasms 7 | 425
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
oligodendroglioma 7 | 2,850
Blepharoptosis 6 | 231
Byzanthine arch palate 6 | 194
Carnitine palmitoyltransferase II deficiency 6 | 14
Feeding difficulties in infancy 6 | 175
Low set ears 6 | 181
Obesity 6 | 678
Pick disease 6 | 1,894
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Strabismus 6 | 270
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Agenesis of corpus callosum 5 | 83
Astrocytoma, Pilocytic 5 | 3,081
Atrial Septal Defects 5 | 85
Cardiac Arrhythmia 5 | 103
Cardiac conduction abnormalities 5 | 78
Conduction disorder of the heart 5 | 79
Crohn's disease 5 | 321
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Pectus excavatum 5 | 100
Respiratory distress 5 | 43
Ventricular Septal Defects 5 | 119
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
Bladder Neoplasm 4 | 112
Delayed speech and language development 4 | 112
Dystonia 4 | 164
Endometrial cancer 4 | 311
Exophthalmos 4 | 112
Failure to gain weight 4 | 365
Hepatomegaly 4 | 285
Highly variable severity 4 | 157
Language Delay 4 | 112
Melanoma 4 | 711
Neurodegenerative disease 4 | 414
Pediatric failure to thrive 4 | 365
Prominent eyes 4 | 96
Protruding eyes 4 | 96
Schizophrenia 4 | 1,160
Speech Delay 4 | 112
Speech impairment 4 | 112
Urinary Bladder Neoplasms 4 | 114
Variable expressivity 4 | 157
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
beta-ketothiolase deficiency 4 | 13
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
medulloblastoma 4 | 720
nephrosclerosis 4 | 333
pituitary cancer 4 | 1,972

Tissue

Endocrine System 67 | 18,159
Female tissues 66 | 17,400
Nervous System 66 | 16,725
Skin and soft tissues 66 | 17,230
Liver and Pancreas 65 | 16,750
Male tissues 65 | 17,142
Blood and immune system 64 | 16,909
Digestive Tract 64 | 17,369
Cardiovascular System 62 | 15,192
Respiratory system 62 | 16,393
Urinary Tract 61 | 16,678

Target Family

Enzyme 41 | 4,145
Epigenetic 18 | 242
Non-IDG 7 | 12,091
Kinase 1 | 634
TF/Epigenetic 1 | 38

PANTHER Protein Class (1)

acetyltransferase 68 | 68
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Enoyl-CoA delta isomerase 1, mitochondrial ECI1 Tbio Enzyme -2.67168 459.1 229
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Peroxisomal carnitine O-octanoyltransferase CROT Tbio Enzyme -1.33388 20.1 252
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Acetyl-CoA acetyltransferase, cytosolic ACAT2 Tbio Enzyme -1.75917 52.6 283
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.38489 225.0 306
N-alpha-acetyltransferase 15, NatA auxiliary subunit NAA15 Tbio Enzyme -2.09909 118.0 157
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial ECHDC2 Tdark Enzyme -0.15970 1.42 76
Putative N-acetyltransferase 8B NAT8B Tbio Enzyme 0.00000 0
N-alpha-acetyltransferase 10 NAA10 Tbio Enzyme -2.42216 249.3 108