Development Level

Tbio 24 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
decreased circulating glucose ... 2 | 126
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal neural tube closure 1 | 46
absent vibrissae 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased monocyte cell number 1 | 8
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
tremors 1 | 39

Disease

Carcinoma 18 | 11,493
osteosarcoma 12 | 7,950
psoriasis 11 | 6,694
Cancer 9 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
lung cancer 8 | 4,740
ovarian cancer 8 | 8,520
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
ulnar-mammary syndrome 7 | 8
Breast cancer 6 | 3,578
Cleft Palate 6 | 271
group 3 medulloblastoma 6 | 4,104
medulloblastoma, large-cell 6 | 6,241
Autosomal recessive predisposition 5 | 1,442
Congenital heart disease 5 | 93
Holt-Oram syndrome 5 | 12
Short stature 5 | 531
Uranostaphyloschisis 5 | 167
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
ulcerative colitis 5 | 1,819
DiGeorge syndrome 4 | 47
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
Short neck 4 | 140
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Delayed speech and language development 3 | 112
Epilepsy 3 | 792
Fetal Growth Retardation 3 | 189
Frontal bossing 3 | 157
Heat Stroke 3 | 13
Hydronephrosis 3 | 89
Hypoplastic mandible condyle 3 | 275
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Language Delay 3 | 112
Long fingers 3 | 9
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Obesity 3 | 678
Orbital separation excessive 3 | 244
Patent ductus arteriosus 3 | 90
Seizures 3 | 596
Small head 3 | 374
Speech Delay 3 | 112
Speech impairment 3 | 112
Ventricular Septal Defects 3 | 119
adult high grade glioma 3 | 3,801
glioblastoma 3 | 5,792
non-small cell lung cancer 3 | 2,890
pulmonary arterial hypertension 3 | 75
sonic hedgehog group medulloblastoma 3 | 467
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Ankyloglossia 2 | 17
Arthritis 2 | 290
Bilateral fifth finger clinodactyly 2 | 110
Blepharophimosis 2 | 70
Broad flat nasal bridge 2 | 236
Cardiomyopathy 2 | 116
Colitis 2 | 54
Colonic Neoplasms 2 | 142
Congenital clubfoot 2 | 109
Congenital deafness 2 | 185
Congenital ocular coloboma (disorder) 2 | 40
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Deafness 2 | 198
Depressive disorder 2 | 409
Hearing Loss, Partial 2 | 185
Hernia, Inguinal 2 | 89
Hip Dislocation, Congenital 2 | 48
Microcephaly 2 | 166
Multiple Sclerosis 2 | 540
Nasal bridge wide 2 | 236
Neoplasm Invasiveness 2 | 161
Osteoporosis 2 | 363
Psychomotor retardation, moderate 2 | 6
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
Schizophrenia 2 | 1,160
Short palpebral fissure 2 | 38
Short philtrum 2 | 53
Syndactyly of the toes 2 | 45
Upward slant of palpebral fissure 2 | 75
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
spina bifida 2 | 1,074

Tissue

Endocrine System 25 | 18,159
Digestive Tract 23 | 17,369
Blood and immune system 22 | 16,909
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Skin and soft tissues 22 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192
Respiratory system 20 | 16,393
Nervous System 19 | 16,725

Target Family

Transcription Factor 25 | 1,400

PANTHER Protein Class (1)

Rel homology transcription fac... 25 | 25
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
T-box transcription factor TBX6 TBX6 Tbio Transcription Factor -1.78720 63.0 315
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
Brachyury protein TBXT Tbio Transcription Factor -2.24737 158.4 337
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Nuclear factor of activated T-cells 5 NFAT5 Tbio Transcription Factor -2.23838 214.7 193
MAX gene-associated protein MGA Tbio Transcription Factor -0.85532 6.90 42