Development Level

Tbio 369 | 11,445
Tdark 104 | 6,588
Tchem 10 | 1,598

IMPC Phenotype

preweaning lethality, complete... 48 | 979
embryonic lethality prior to o... 15 | 239
embryonic lethality prior to t... 11 | 278
preweaning lethality, incomple... 10 | 499
abnormal embryo size 8 | 220
abnormal behavior 7 | 298
embryonic growth retardation 6 | 106
hypoactivity 5 | 132
abnormal bone structure 4 | 187
hyperactivity 4 | 148
abnormal behavioral response t... 3 | 66
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased grip strength 3 | 116
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular hem... 3 | 31
decreased total body fat amoun... 3 | 207
increased circulating alkaline... 3 | 122
increased circulating free fat... 3 | 20
increased lean body mass 3 | 172
increased mean platelet volume 3 | 45
increased vertical activity 3 | 24
male infertility 3 | 123
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating sodium l... 2 | 22
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
enlarged lymph nodes 2 | 37
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased circulating iron lev... 2 | 30
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
corneal opacity 1 | 32
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
enlarged urinary bladder 1 | 8
hemorrhage 1 | 23
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body temperature 1 | 9
increased circulating calcium ... 1 | 34
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8
vertebral transformation 1 | 12

Disease

ovarian cancer 261 | 8,520
Carcinoma 233 | 11,493
osteosarcoma 197 | 7,950
lung cancer 148 | 4,740
medulloblastoma, large-cell 147 | 6,241
psoriasis 139 | 6,694
glioblastoma 120 | 5,792
group 3 medulloblastoma 116 | 4,104
atypical teratoid / rhabdoid tumor 102 | 5,112
Multiple myeloma 100 | 1,332
ependymoma 93 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 80 | 3,291
Breast cancer 76 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 70 | 2,989
acute quadriplegic myopathy 66 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
oligodendroglioma 65 | 2,850
primitive neuroectodermal tumor 65 | 3,035
malignant mesothelioma 63 | 3,232
astrocytic glioma 60 | 2,597
adult high grade glioma 59 | 3,801
non-small cell lung cancer 53 | 2,890
Waldenstrons macroglobulinemia 52 | 765
diabetes mellitus 52 | 1,728
lung adenocarcinoma 52 | 2,716
Kidney cancer 50 | 2,613
invasive ductal carcinoma 50 | 2,951
Pick disease 49 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,962
dermatomyositis 45 | 966
subependymal giant cell astrocytoma 43 | 2,287
astrocytoma 39 | 1,146
Cancer 38 | 2,499
group 4 medulloblastoma 37 | 1,855
acute myeloid leukemia 35 | 783
Astrocytoma, Pilocytic 32 | 3,081
non primary Sjogren syndrome sicca 32 | 891
pancreatic cancer 32 | 2,398
juvenile dermatomyositis 30 | 1,187
Intellectual disability 29 | 1,016
breast carcinoma 29 | 1,638
pediatric high grade glioma 28 | 1,064
progressive supranuclear palsy 28 | 676
colon cancer 27 | 1,478
primary pancreatic ductal adenocarcinoma 24 | 1,109
Diamond-Blackfan anemia 22 | 31
cystic fibrosis 22 | 1,696
Rheumatoid arthritis 21 | 1,191
lung carcinoma 21 | 2,843
sonic hedgehog group medulloblastoma 21 | 467
Short stature 20 | 531
ductal carcinoma in situ 20 | 1,745
pituitary cancer 20 | 1,972
Amyotrophic lateral sclerosis 19 | 451
adrenocortical carcinoma 19 | 1,428
tuberculosis 19 | 2,010
Autosomal recessive predisposition 18 | 1,442
Breast Neoplasms 18 | 445
Cleft Palate 18 | 271
Cognitive delay 18 | 608
Global developmental delay 18 | 608
Mammary Neoplasms 18 | 425
Mental and motor retardation 18 | 608
aldosterone-producing adenoma 18 | 665
nasopharyngeal carcinoma 18 | 1,058
Dull intelligence 17 | 645
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Uranostaphyloschisis 17 | 167
hepatocellular carcinoma 17 | 547
spina bifida 17 | 1,074
Adenocarcinoma of lung 16 | 142
Anemia 16 | 365
Disease Models, Animal 16 | 155
Small head 16 | 374
tuberculosis and treatment for 6 months 15 | 409
Delayed Puberty 14 | 97
Epilepsy 14 | 792
Schizophrenia 14 | 1,160
Stomach Neoplasms 14 | 300
ulcerative colitis 14 | 1,819
Disease Progression 13 | 136
Fatigue 13 | 182
Gaucher disease type 1 13 | 180
hereditary spastic paraplegia 13 | 318
HIV Infections 12 | 102
Infertility 12 | 188
gastric carcinoma 12 | 807
mucosa-associated lymphoid tissue lymphoma 12 | 484
Cardiac Arrhythmia 11 | 103
Cardiac conduction abnormalities 11 | 78
Conduction disorder of the heart 11 | 79
EKG abnormalities 11 | 78
Electrocardiogram abnormal 11 | 81
Electrocardiogram change 11 | 78
Migraine Disorders 11 | 76
Pallor 11 | 40
pancreatic carcinoma 11 | 562

Tissue

Endocrine System 470 | 18,159
Digestive Tract 457 | 17,369
Female tissues 452 | 17,400
Male tissues 452 | 17,142
Skin and soft tissues 451 | 17,230
Nervous System 450 | 16,725
Blood and immune system 448 | 16,909
Liver and Pancreas 448 | 16,750
Urinary Tract 448 | 16,678
Respiratory system 447 | 16,393
Cardiovascular System 442 | 15,192

Target Family

Non-IDG 402 | 12,091
Enzyme 65 | 4,145
Transcription Factor 14 | 1,400
Epigenetic 2 | 242

PANTHER Protein Class (1)

RNA binding protein 483 | 483
protease 516 | 516
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/arginine-rich splicing factor 12 SRSF12 Tbio Non-IDG -0.09691 1.17 22
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.33579 2.63 48
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
RNA-binding motif protein, Y chromosome, family 1 member B RBMY1B Tbio Non-IDG 0.00000 2
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.39993 250.5 121
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
La-related protein 6 LARP6 Tbio Non-IDG -1.42450 28.5 86