Development Level

Tbio 111 | 11,445
Tdark 15 | 6,588
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 7 | 499
decreased bone mineral content 5 | 151
decreased body weight 4 | 161
short tibia 4 | 97
abnormal behavior 3 | 298
decreased body length 3 | 101
decreased circulating iron lev... 3 | 32
embryonic lethality prior to t... 3 | 278
abnormal cranium morphology 2 | 36
decreased circulating phosphat... 2 | 27
decreased lean body mass 2 | 135
decreased spleen weight 2 | 10
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
enlarged spleen 1 | 41
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small spleen 1 | 19
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 78 | 11,493
ovarian cancer 76 | 8,520
glioblastoma 71 | 5,792
medulloblastoma, large-cell 65 | 6,241
osteosarcoma 64 | 7,950
psoriasis 54 | 6,694
atypical teratoid / rhabdoid tumor 53 | 5,112
ependymoma 53 | 4,679
adult high grade glioma 48 | 3,801
lung cancer 39 | 4,740
Astrocytoma, Pilocytic 38 | 3,081
Breast cancer 37 | 3,578
group 3 medulloblastoma 35 | 4,104
lung carcinoma 35 | 2,843
oligodendroglioma 35 | 2,850
astrocytic glioma 34 | 2,597
primitive neuroectodermal tumor 34 | 3,035
subependymal giant cell astrocytoma 33 | 2,287
invasive ductal carcinoma 32 | 2,951
Cancer 27 | 2,499
Pick disease 26 | 1,894
group 4 medulloblastoma 25 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
lung adenocarcinoma 25 | 2,716
non-small cell lung cancer 25 | 2,890
pancreatic cancer 25 | 2,398
malignant mesothelioma 24 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
juvenile dermatomyositis 19 | 1,187
Multiple myeloma 18 | 1,332
primary pancreatic ductal adenocarcinoma 18 | 1,109
astrocytoma 17 | 1,146
ductal carcinoma in situ 17 | 1,745
interstitial cystitis 17 | 2,312
pituitary cancer 16 | 1,972
acute quadriplegic myopathy 15 | 1,158
colon cancer 15 | 1,478
ulcerative colitis 15 | 1,819
Rheumatoid arthritis 14 | 1,191
breast carcinoma 14 | 1,638
pediatric high grade glioma 13 | 1,064
primary Sjogren syndrome 13 | 735
Kidney cancer 12 | 2,613
active Crohn's disease 12 | 922
cystic fibrosis 12 | 1,696
diabetes mellitus 12 | 1,728
active ulcerative colitis 11 | 764
cutaneous lupus erythematosus 11 | 1,057
dermatomyositis 11 | 966
nasopharyngeal carcinoma 11 | 1,058
Waldenstrons macroglobulinemia 10 | 765
Melanoma 9 | 711
tuberculosis 9 | 2,010
Liver Cirrhosis, Experimental 8 | 769
Schizophrenia 8 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
sarcoidosis 8 | 370
Blepharoptosis 7 | 231
Duchenne muscular dystrophy 7 | 601
Hemangioma 7 | 69
Intellectual disability 7 | 1,016
Short stature 7 | 531
Strabismus 7 | 270
gastric cancer 7 | 459
hepatocellular carcinoma 7 | 547
progressive supranuclear palsy 7 | 676
Abnormal dermatoglyphic pattern 6 | 24
Acquired scoliosis 6 | 281
Byzanthine arch palate 6 | 194
Curvature of spine 6 | 282
Joint hyperflexibility 6 | 78
Low set ears 6 | 181
Muscle hypotonia 6 | 571
adrenocortical carcinoma 6 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
esophageal adenocarcinoma 6 | 737
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
spina bifida 6 | 1,074
Aortic coarctation 5 | 30
Cardiac Arrhythmia 5 | 103
Cerebral atrophy 5 | 178
Conduction disorder of the heart 5 | 79
Depressive disorder 5 | 409
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Epilepsy 5 | 792
Heart disease 5 | 306
Hyperreflexia 5 | 209
Hypertension 5 | 396
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
Parkinson's disease 5 | 392
Seizures 5 | 596
Skin cancer 5 | 469
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
fibroadenoma 5 | 559

Tissue

Endocrine System 129 | 18,159
Digestive Tract 125 | 17,369
Skin and soft tissues 125 | 17,230
Female tissues 124 | 17,400
Nervous System 124 | 16,725
Male tissues 122 | 17,142
Respiratory system 122 | 16,393
Blood and immune system 121 | 16,909
Liver and Pancreas 120 | 16,750
Urinary Tract 120 | 16,678
Cardiovascular System 115 | 15,192

Target Family

Non-IDG 77 | 12,091
Enzyme 54 | 4,145

PANTHER Protein Class (1)

G-protein 131 | 131
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
DDB1- and CUL4-associated factor 8-like protein 1 DCAF8L1 Tdark Non-IDG 0.00000 4
Septin-9 SEPT9 Tbio Non-IDG -2.20898 161.9 130
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Guanylate-binding protein 7 GBP7 Tdark Non-IDG -0.45484 2.62 54
Importin-11 IPO11 Tbio Non-IDG -0.74763 5.44 154
Transmembrane protein 250 TMEM250 Tdark Non-IDG 0.00000 1.00 3