Development Level

Tbio 52 | 11,445
Tdark 10 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

decreased total body fat amoun... 7 | 207
decreased circulating insulin ... 4 | 76
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal heart morphology 3 | 162
abnormal seminal vesicle morph... 3 | 114
decreased body weight 3 | 161
decreased circulating HDL chol... 3 | 68
decreased circulating glucose ... 3 | 126
decreased vertical activity 3 | 208
enlarged heart 3 | 210
increased bone mineral content 3 | 108
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal maxilla morphology 2 | 17
abnormal spleen morphology 2 | 55
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged spleen 2 | 41
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal coping response 1 | 1
abnormal cornea morphology 1 | 31
abnormal digestive system phys... 1 | 1
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent adrenal gland 1 | 2
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating magnesiu... 1 | 13
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
prenatal lethality 1 | 28
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 51 | 11,493
ovarian cancer 38 | 8,520
medulloblastoma, large-cell 32 | 6,241
glioblastoma 30 | 5,792
atypical teratoid / rhabdoid tumor 29 | 5,112
osteosarcoma 28 | 7,950
ependymoma 25 | 4,679
Astrocytoma, Pilocytic 23 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
adult high grade glioma 22 | 3,801
group 3 medulloblastoma 22 | 4,104
psoriasis 21 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung carcinoma 19 | 2,843
astrocytic glioma 17 | 2,597
invasive ductal carcinoma 17 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
lung cancer 16 | 4,740
oligodendroglioma 16 | 2,850
pancreatic cancer 16 | 2,398
non-small cell lung cancer 15 | 2,890
lung adenocarcinoma 14 | 2,716
ductal carcinoma in situ 13 | 1,745
subependymal giant cell astrocytoma 13 | 2,287
Kidney cancer 11 | 2,613
Schizophrenia 11 | 1,160
interstitial cystitis 11 | 2,312
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 10 | 3,578
breast carcinoma 10 | 1,638
malignant mesothelioma 10 | 3,232
ulcerative colitis 10 | 1,819
group 4 medulloblastoma 9 | 1,855
Pick disease 8 | 1,894
spina bifida 8 | 1,074
Cancer 7 | 2,499
Down syndrome 7 | 499
Prostatic Neoplasms 7 | 495
Rheumatoid arthritis 7 | 1,191
active Crohn's disease 7 | 922
dermatomyositis 7 | 966
juvenile dermatomyositis 7 | 1,187
pancreatic carcinoma 7 | 562
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
primary pancreatic ductal adenocarcinoma 6 | 1,109
Amyotrophic lateral sclerosis 5 | 451
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Duchenne muscular dystrophy 5 | 601
Intellectual disability 5 | 1,016
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
colon cancer 5 | 1,478
fibroadenoma 5 | 559
tuberculosis 5 | 2,010
Acquired metabolic disease 4 | 336
Autistic Disorder 4 | 364
Liver Cirrhosis, Experimental 4 | 769
Major Depressive Disorder 4 | 301
Multiple myeloma 4 | 1,332
Neoplasm Metastasis 4 | 168
Polycystic ovary syndrome 4 | 360
Unipolar Depression 4 | 250
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
esophageal adenocarcinoma 4 | 737
nasopharyngeal carcinoma 4 | 1,058
Autism spectrum disorder 3 | 101
Cardiomyopathy 3 | 116
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Heart disease 3 | 306
Hepatomegaly 3 | 285
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Neoplasm Invasiveness 3 | 161
Neurodevelopmental Disorders 3 | 70
Nystagmus 3 | 317
Short stature 3 | 531
Silver-Russell syndrome 3 | 39
Weight Gain 3 | 100
aldosterone-producing adenoma 3 | 665
interstitial lung disease 3 | 298
obsessive-compulsive disorder 3 | 61
primary Sjogren syndrome 3 | 735
tuberculosis and treatment for 3 months 3 | 179
Alzheimer's disease 2 | 658
Atherosclerosis 2 | 291
Atrial Fibrillation 2 | 124
Cerebrovascular disease 2 | 238
Disease of mental health 2 | 36
Epilepsy 2 | 792
Glaucoma 2 | 239
Hypertension 2 | 396
Lung disease 2 | 142
Vascular disease 2 | 319

Tissue

Endocrine System 64 | 18,159
Female tissues 63 | 17,400
Male tissues 62 | 17,142
Digestive Tract 61 | 17,369
Nervous System 61 | 16,725
Skin and soft tissues 61 | 17,230
Blood and immune system 60 | 16,909
Urinary Tract 59 | 16,678
Liver and Pancreas 58 | 16,750
Respiratory system 57 | 16,393
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 56 | 12,091
Enzyme 4 | 4,145
Transporter 4 | 473

PANTHER Protein Class (0)

transmembrane receptor regulat... 64 | 64
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caskin-2 CASKIN2 Tdark Non-IDG -0.21450 1.97 118
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
GRB2-associated-binding protein 3 GAB3 Tbio Non-IDG -0.78182 5.77 104
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Disks large-associated protein 3 DLGAP3 Tbio Non-IDG -1.26274 19.1 94
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Serine incorporator 4 SERINC4 Tdark Non-IDG 0.00000 33