Development Level

Tbio 109 | 11,651
Tdark 35 | 6,593
Tchem 27 | 1,388
Tclin 4 | 612

Collection

Kinase: IDG Consortium (Target... 9 | 125
RFA-RM-18-021 9 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
abnormal seminal vesicle morph... 3 | 114
abnormal testis morphology 3 | 43
decreased body weight 3 | 161
enlarged heart 3 | 210
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal sleep behavior 2 | 70
decreased circulating choleste... 2 | 93
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
increased bone mineral content 2 | 108
increased circulating LDL chol... 2 | 13
increased circulating alanine ... 2 | 13
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
abnormal joint morphology 1 | 23
abnormal retinal blood vessel ... 1 | 26
brachydactyly 1 | 19
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
embryonic lethality prior to o... 1 | 239
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body temperature 1 | 9
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
male infertility 1 | 123
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

Carcinoma 103 | 11,493
ovarian cancer 83 | 8,520
osteosarcoma 75 | 7,950
medulloblastoma, large-cell 68 | 6,241
glioblastoma 66 | 5,792
psoriasis 63 | 6,694
atypical teratoid / rhabdoid tumor 59 | 5,112
lung cancer 47 | 4,740
group 3 medulloblastoma 46 | 4,104
ependymoma 44 | 4,679
adult high grade glioma 42 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
Astrocytoma, Pilocytic 33 | 3,081
Breast cancer 33 | 3,578
primitive neuroectodermal tumor 33 | 3,035
lung carcinoma 31 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
lung adenocarcinoma 27 | 2,716
invasive ductal carcinoma 26 | 2,951
pancreatic cancer 26 | 2,398
non-small cell lung cancer 24 | 2,890
malignant mesothelioma 23 | 3,232
oligodendroglioma 23 | 2,850
Cancer 21 | 2,499
Pick disease 21 | 1,894
tuberculosis 21 | 2,010
astrocytic glioma 20 | 2,597
subependymal giant cell astrocytoma 20 | 2,287
ulcerative colitis 20 | 1,819
Multiple myeloma 19 | 1,332
adrenocortical carcinoma 19 | 1,428
pituitary cancer 19 | 1,972
diabetes mellitus 18 | 1,728
Schizophrenia 17 | 1,160
spina bifida 17 | 1,074
breast carcinoma 16 | 1,638
interstitial cystitis 16 | 2,312
Kidney cancer 15 | 2,613
astrocytoma 15 | 1,146
pediatric high grade glioma 15 | 1,064
Autosomal recessive predisposition 14 | 1,442
ductal carcinoma in situ 14 | 1,745
group 4 medulloblastoma 14 | 1,855
primary pancreatic ductal adenocarcinoma 14 | 1,109
Liver Cirrhosis, Experimental 13 | 769
Rheumatoid arthritis 13 | 1,191
acute quadriplegic myopathy 13 | 1,158
juvenile dermatomyositis 13 | 1,187
non primary Sjogren syndrome sicca 13 | 891
Epilepsy 12 | 792
Obesity 12 | 678
dermatomyositis 12 | 966
Atopic dermatitis 11 | 952
active Crohn's disease 11 | 922
colon cancer 11 | 1,478
Alzheimer's disease 10 | 658
Intellectual disability 10 | 1,016
active ulcerative colitis 10 | 764
acute myeloid leukemia 10 | 783
cystic fibrosis 10 | 1,696
medulloblastoma 10 | 720
Disease Models, Animal 9 | 155
Hypertension 9 | 396
Kidney disease 9 | 430
Seizures 9 | 596
gastric carcinoma 9 | 807
progressive supranuclear palsy 9 | 676
Cerebellar Ataxia 8 | 304
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
cutaneous lupus erythematosus 8 | 1,057
primary Sjogren syndrome 8 | 735
Adenocarcinoma of lung 7 | 142
Chemical and Drug Induced Liver Injury 7 | 195
Fatty liver disease 7 | 103
Multiple Sclerosis 7 | 540
Stomach Neoplasms 7 | 300
Waldenstrons macroglobulinemia 7 | 765
esophageal adenocarcinoma 7 | 737
fibroadenoma 7 | 559
nasopharyngeal carcinoma 7 | 1,058
Atherosclerosis 6 | 291
Cognitive delay 6 | 608
Down syndrome 6 | 499
Global developmental delay 6 | 608
Liver cancer 6 | 604
Liver disease 6 | 237
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Nystagmus 6 | 317
atypical teratoid/rhabdoid tumor 6 | 357
chronic rhinosinusitis 6 | 512
gastric cancer 6 | 459
pancreatic carcinoma 6 | 562
posterior fossa group A ependymoma 6 | 468

Tissue

Endocrine System 170 | 18,159
Female tissues 169 | 17,400
Skin and soft tissues 168 | 17,230
Digestive Tract 167 | 17,369
Male tissues 167 | 17,142
Liver and Pancreas 166 | 16,750
Blood and immune system 164 | 16,909
Nervous System 163 | 16,725
Urinary Tract 162 | 16,678
Respiratory system 161 | 16,393
Cardiovascular System 158 | 15,192

Target Family

Non-IDG 115 | 12,091
Kinase 33 | 634
Enzyme 18 | 4,145
Transporter 9 | 473

PANTHER Protein Class (0)

transfer/carrier protein 175 | 175
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Exportin-4 XPO4 Tbio Non-IDG -1.62873 40.7 26
Secretoglobin family 1D member 1 SCGB1D1 Tbio Non-IDG -2.15875 142.3 0
Ganglioside GM2 activator GM2A Tbio Non-IDG -2.03952 111.9 325
Collagen type IV alpha-3-binding protein COL4A3BP Tbio Non-IDG -1.84397 60.0 282
Mitochondrial import inner membrane translocase subunit Tim10 B TIMM10B Tdark Enzyme 0.11 0.77 53
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Importin subunit alpha-1 KPNA2 Tbio Non-IDG -1.90187 84.5 281
Exocyst complex component 1 EXOC1 Tbio Non-IDG -1.85438 74.2 51
Solute carrier family 25 member 43 SLC25A43 Tdark Transporter -0.44974 4.34 11
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.88151 7.21 111