Development Level

Tbio 182 | 10,625
Tdark 68 | 7,003
Tchem 50 | 1,890
Tclin 8 | 602

Collection

Eligible Kinase Proteins 9 | 134

IMPC Term

preweaning lethality, complete... 8 | 633
increased circulating alkaline... 5 | 119
abnormal behavior 4 | 226
decreased body weight 4 | 174
abnormal testis morphology 3 | 30
decreased body length 3 | 108
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased lean body mass 3 | 195
decreased leukocyte cell numbe... 3 | 54
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
small testis 3 | 37
abnormal heart morphology 2 | 51
decreased Ly6C high monocyte n... 2 | 18
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating potassiu... 2 | 17
decreased grip strength 2 | 123
decreased monocyte cell number 2 | 28
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased circulating LDL chol... 2 | 15
increased mean corpuscular hem... 2 | 93
abnormal allantois morphology 1 | 3
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal epididymis morphology 1 | 31
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal respiratory quotient 1 | 9
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 21
decreased CD4-positive, CD25-p... 1 | 24
decreased Ly6C low monocyte nu... 1 | 23
decreased NK T cell number 1 | 28
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased follicular B cell nu... 1 | 4
decreased gamma-delta T cell n... 1 | 18
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
hydrometra 1 | 13
hypoactivity 1 | 89
increased Ly6C high monocyte n... 1 | 12
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased marginal zone B cell... 1 | 3
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
oligodactyly 1 | 14
persistence of hyaloid vascula... 1 | 22
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

osteosarcoma 132 | 7,933
ovarian cancer 130 | 8,484
medulloblastoma, large-cell 115 | 6,234
psoriasis 114 | 6,685
glioblastoma 91 | 5,572
atypical teratoid / rhabdoid tumor 74 | 4,369
lung cancer 69 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,289
lung carcinoma 54 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 51 | 1,795
pediatric high grade glioma 48 | 2,712
primitive neuroectodermal tumor 48 | 3,031
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,956
pilocytic astrocytoma 47 | 3,086
Breast cancer 46 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 46 | 2,988
adult high grade glioma 44 | 2,148
lung adenocarcinoma 44 | 2,713
malignant mesothelioma 43 | 3,162
ependymoma 41 | 2,514
invasive ductal carcinoma 41 | 2,950
ulcerative colitis 40 | 2,087
Pick disease 39 | 1,893
oligodendroglioma 39 | 2,849
non-small cell lung cancer 37 | 2,798
pancreatic cancer 37 | 2,300
subependymal giant cell astrocytoma 37 | 2,287
diabetes mellitus 35 | 1,663
medulloblastoma 34 | 1,524
pituitary cancer 34 | 1,972
group 3 medulloblastoma 33 | 2,254
group 4 medulloblastoma 33 | 1,875
Cancer 30 | 2,346
astrocytoma 30 | 1,493
astrocytic glioma 29 | 2,241
interstitial cystitis 28 | 2,299
adrenocortical carcinoma 27 | 1,427
breast carcinoma 27 | 1,614
posterior fossa group A ependymoma 26 | 1,511
atypical teratoid/rhabdoid tumor 25 | 1,095
ductal carcinoma in situ 25 | 1,745
Multiple myeloma 24 | 1,327
acute quadriplegic myopathy 24 | 1,157
primary pancreatic ductal adenocarcinoma 24 | 1,271
tuberculosis 24 | 1,557
Rheumatoid Arthritis 21 | 1,160
Obesity 20 | 616
juvenile dermatomyositis 20 | 1,189
posterior fossa group B ependymoma 20 | 1,530
spina bifida 20 | 1,064
colon cancer 19 | 1,475
non primary Sjogren syndrome sicca 19 | 840
Carcinoma 18 | 2,147
active Crohn's disease 18 | 918
cystic fibrosis 18 | 1,665
dermatomyositis 18 | 933
sonic hedgehog group medulloblastoma 18 | 1,482
Anemia 17 | 252
Atopic dermatitis 16 | 944
progressive supranuclear palsy 16 | 674
Kidney disease 15 | 396
acute myeloid leukemia 15 | 780
gastric carcinoma 15 | 832
Alzheimer's disease 14 | 644
chronic rhinosinusitis 14 | 512
Waldenstrons macroglobulinemia 13 | 765
active ulcerative colitis 12 | 477
Crohn's disease 11 | 304
Prostatic Neoplasms 11 | 471
cutaneous lupus erythematosus 11 | 1,056
glioblastoma multiforme 11 | 347
mucosa-associated lymphoid tissue lymphoma 11 | 480
nasopharyngeal carcinoma 11 | 1,056
Atherosclerosis 10 | 275
Down syndrome 10 | 548
Duchenne muscular dystrophy 10 | 602
Metabolic syndrome X 10 | 155
Multiple Sclerosis 10 | 498
Thalassemia 10 | 46
nephrosclerosis 10 | 329
primary Sjogren syndrome 10 | 789
Coronary artery disease 9 | 240
Heart disease 9 | 279
Schizophrenia 9 | 501
esophageal adenocarcinoma 9 | 737
hepatocellular carcinoma 9 | 532
pancreatic carcinoma 9 | 567
Epilepsy 8 | 346
Fatty liver disease 8 | 84
Hypertensive disease 8 | 193
Liver disease 8 | 219
Malaria 8 | 140
Mammary Neoplasms, Experimental 8 | 150
Peripheral Neuropathy 8 | 303
fibroadenoma 8 | 557
tuberculosis and treatment for 3 months 8 | 327
tuberculosis and treatment for 6 months 8 | 686
Lipid metabolism disorder 7 | 102
Vascular disease 7 | 281
aldosterone-producing adenoma 7 | 664

Tissue

Nervous System 302 | 18,561
Digestive Tract 301 | 18,473
Urinary Tract 301 | 18,444
Endocrine System 300 | 18,512
Female tissues 300 | 18,647
Skin and soft tissues 299 | 18,115
Liver and Pancreas 298 | 18,136
Blood and immune system 297 | 17,995
Cardiovascular System 295 | 17,958
Male tissues 292 | 17,969
Respiratory system 290 | 17,484

Target Family

Non-IDG 178 | 11,971
Transporter 70 | 473
Kinase 41 | 634
Enzyme 19 | 4,146

PANTHER Protein Class (0)

transfer/carrier protein 308 | 308
transcription factor 1,533 | 1,533
nucleic acid binding 1,330 | 1,330
transferase 873 | 873
signaling molecule 820 | 820
transporter 767 | 767
enzyme modulator 713 | 713
hydrolase 631 | 631
cytoskeletal protein 608 | 608
receptor 550 | 550
cell adhesion molecule 502 | 502
oxidoreductase 404 | 404
ligase 291 | 291
membrane traffic protein 285 | 285
extracellular matrix protein 262 | 262
defense/immunity protein 209 | 209
chaperone 163 | 163
isomerase 152 | 152
calcium-binding protein 149 | 149
cell junction protein 129 | 129
lyase 109 | 109
transmembrane receptor regulat... 68 | 68
surfactant 53 | 53
structural protein 42 | 42
storage protein 18 | 18
viral protein 13 | 13

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.46900 2.68 102
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
VPS10 domain-containing receptor SorCS3 SORCS3 Tbio Non-IDG -0.54622 5.51 46
Apolipoprotein C-II APOC2 Tbio Non-IDG -2.49982 337.4 18
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.80284 593.9 352
Serine/threonine-protein kinase N3 PKN3 Tchem Kinase -1.11681 14.4 104
Hemopexin HPX Tbio Non-IDG -2.83364 677.6 363
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transthyretin TTR Tclin Non-IDG -3.74965 5822.8 617