Development Level

Tbio 169 | 11,651
Tclin 83 | 612
Tchem 78 | 1,388
Tdark 70 | 6,593

Collection

GPCR: IDG Consortium (Targets) 43 | 126
RFA-RM-18-021 42 | 328
GPCR: IDG Consortium (Complete... 7 | 25
Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal behavior 12 | 298
decreased vertical activity 10 | 208
preweaning lethality, incomple... 10 | 499
preweaning lethality, complete... 9 | 979
abnormal bone structure 8 | 187
decreased total body fat amoun... 8 | 207
enlarged heart 7 | 210
hyperactivity 7 | 148
decreased heart weight 5 | 27
hypoactivity 5 | 132
increased mean corpuscular vol... 5 | 92
male infertility 5 | 123
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
embryonic lethality prior to t... 4 | 278
female infertility 4 | 60
improved glucose tolerance 4 | 79
increased circulating sodium l... 4 | 71
increased lean body mass 4 | 172
increased or absent threshold ... 4 | 101
abnormal embryo size 3 | 220
abnormal eye anterior chamber ... 3 | 9
abnormal gait 3 | 69
abnormal kidney morphology 3 | 65
abnormal skin coloration 3 | 25
abnormal sleep behavior 3 | 70
cardiovascular system phenotyp... 3 | 36
decreased bone mineral content 3 | 151
decreased circulating alanine ... 3 | 47
decreased heart rate 3 | 18
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
decreased startle reflex 3 | 75
embryonic lethality prior to o... 3 | 239
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased circulating choleste... 3 | 66
increased fasted circulating g... 3 | 76
increased heart rate 3 | 23
increased mean platelet volume 3 | 45
increased monocyte cell number 3 | 63
increased total body fat amoun... 3 | 134
limb grasping 3 | 41
small superior vagus ganglion 3 | 74
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal colon morphology 2 | 3
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal liver morphology 2 | 17
abnormal retinal blood vessel ... 2 | 26
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
abnormal testis morphology 2 | 43
abnormal vertebrae morphology 2 | 18
absent vibrissae 2 | 12
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 36
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased eosinophil cell numb... 2 | 24
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased mean platelet volume 2 | 25
decreased threshold for audito... 2 | 26
edema 2 | 59
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
increased circulating HDL chol... 2 | 80
increased circulating creatini... 2 | 38
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
increased vertical activity 2 | 24
microphthalmia 2 | 26
prolonged QT interval 2 | 38
prolonged RR interval 2 | 8
prolonged ST segment 2 | 36
small adrenal glands 2 | 16
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased startle reflex 1 | 112
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 283 | 11,493
osteosarcoma 158 | 7,950
psoriasis 149 | 6,694
ovarian cancer 142 | 8,520
medulloblastoma, large-cell 133 | 6,241
glioblastoma 121 | 5,792
atypical teratoid / rhabdoid tumor 103 | 5,112
ependymoma 92 | 4,679
lung cancer 92 | 4,740
adult high grade glioma 86 | 3,801
Astrocytoma, Pilocytic 80 | 3,081
invasive ductal carcinoma 77 | 2,951
group 3 medulloblastoma 75 | 4,104
lung adenocarcinoma 73 | 2,716
malignant mesothelioma 72 | 3,232
interstitial cystitis 71 | 2,312
lung carcinoma 71 | 2,843
Schizophrenia 68 | 1,160
non-small cell lung cancer 68 | 2,890
Breast cancer 63 | 3,578
primitive neuroectodermal tumor 60 | 3,035
Cancer 58 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,989
Kidney cancer 57 | 2,613
astrocytic glioma 56 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,291
oligodendroglioma 55 | 2,850
ulcerative colitis 53 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 52 | 2,955
pituitary cancer 50 | 1,972
pancreatic cancer 48 | 2,398
Bipolar Disorder 44 | 666
ductal carcinoma in situ 41 | 1,745
tuberculosis 41 | 2,010
breast carcinoma 40 | 1,638
diabetes mellitus 40 | 1,728
adrenocortical carcinoma 39 | 1,428
subependymal giant cell astrocytoma 38 | 2,287
Depressive disorder 36 | 409
Obesity 36 | 678
cutaneous lupus erythematosus 36 | 1,057
Major Depressive Disorder 35 | 301
Asthma 34 | 385
Autosomal recessive predisposition 32 | 1,442
Alcoholic Intoxication, Chronic 31 | 289
Mood Disorders 31 | 184
colon cancer 31 | 1,478
cystic fibrosis 30 | 1,696
group 4 medulloblastoma 30 | 1,855
Epilepsy 29 | 792
Mental Depression 29 | 333
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
juvenile dermatomyositis 27 | 1,187
Parkinson's disease 26 | 392
Unipolar Depression 26 | 250
primary Sjogren syndrome 26 | 735
Allergic rhinitis 25 | 95
Atopic dermatitis 25 | 952
Liver Cirrhosis, Experimental 25 | 769
Attention deficit hyperactivity disorder 23 | 278
Pick disease 23 | 1,894
gastric carcinoma 23 | 807
Melanoma 22 | 711
Multiple Sclerosis 22 | 540
Rheumatoid arthritis 22 | 1,191
Alzheimer's disease 21 | 658
Hypertension 21 | 396
acute quadriplegic myopathy 21 | 1,158
fibroadenoma 21 | 559
medulloblastoma 21 | 720
Migraine 20 | 83
Seizures 20 | 596
astrocytoma 20 | 1,146
mucosa-associated lymphoid tissue lymphoma 20 | 484
primary pancreatic ductal adenocarcinoma 20 | 1,109
Autistic Disorder 19 | 364
Common cold 19 | 69
Duchenne muscular dystrophy 19 | 601
Nasal congestion 19 | 23
Nasal discharge 19 | 25
aldosterone-producing adenoma 19 | 665
pediatric high grade glioma 19 | 1,064
active ulcerative colitis 18 | 764
Alcohol dependence 17 | 107
Intellectual disability 16 | 1,016
Pain 16 | 103
Pain agnosia 16 | 104
Skin cancer 16 | 469
head and neck cancer and chronic obstructive pulmonary disease 16 | 239
Waldenstrons macroglobulinemia 15 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
dermatomyositis 15 | 966
non primary Sjogren syndrome sicca 15 | 891
spina bifida 15 | 1,074
Cocaine-Related Disorders 14 | 92
Hypertensive disease 14 | 292
Liver cancer 14 | 604
active Crohn's disease 14 | 922
esophageal adenocarcinoma 14 | 737
nasopharyngeal carcinoma 14 | 1,058

Tissue

Endocrine System 366 | 18,159
Nervous System 340 | 16,725
Digestive Tract 339 | 17,369
Female tissues 338 | 17,400
Skin and soft tissues 329 | 17,230
Male tissues 325 | 17,142
Blood and immune system 317 | 16,909
Liver and Pancreas 314 | 16,750
Urinary Tract 312 | 16,678
Respiratory system 298 | 16,393
Cardiovascular System 274 | 15,192

Target Family

GPCR 191 | 408
Non-IDG 152 | 12,091
Enzyme 19 | 4,145
oGPCR 17 | 421
Kinase 15 | 634
Transporter 3 | 473
Ion Channel 2 | 344
Epigenetic 1 | 242

PANTHER Protein Class (0)

receptor 400 | 400
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Solute carrier family 52, riboflavin transporter, member 3 SLC52A3 Tbio Transporter -1.82473 71.3 31
Opsin-5 OPN5 Tbio GPCR -1.19753 14.2 151
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Neurotrypsin PRSS12 Tbio Non-IDG -1.46986 30.6 77
Sphingosine 1-phosphate receptor 4 S1PR4 Tclin GPCR -1.78966 58.4 256
Membrane progestin receptor gamma PAQR5 Tbio Non-IDG -0.86721 7.03 64
Malignant T-cell-amplified sequence 1 MCTS1 Tbio Non-IDG -0.79616 5.89 149