Development Level

Tbio 45 | 11,445
Tchem 8 | 1,598
Tdark 7 | 6,588
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal digit morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
decreased IgM level 1 | 1
decreased body length 1 | 101
decreased body weight 1 | 161
decreased mean corpuscular vol... 1 | 79
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 42 | 11,493
ovarian cancer 36 | 8,520
osteosarcoma 25 | 7,950
psoriasis 25 | 6,694
lung cancer 23 | 4,740
medulloblastoma, large-cell 22 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
Autosomal recessive predisposition 17 | 1,442
glioblastoma 17 | 5,792
invasive ductal carcinoma 17 | 2,951
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 13 | 4,679
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung carcinoma 13 | 2,843
Multiple myeloma 12 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
malignant mesothelioma 12 | 3,232
oligodendroglioma 12 | 2,850
Cancer 11 | 2,499
lung adenocarcinoma 11 | 2,716
Seizures 10 | 596
adult high grade glioma 10 | 3,801
colon cancer 10 | 1,478
diabetes mellitus 10 | 1,728
tuberculosis 10 | 2,010
Astrocytoma, Pilocytic 9 | 3,081
Epilepsy 9 | 792
Pick disease 9 | 1,894
interstitial cystitis 9 | 2,312
primitive neuroectodermal tumor 9 | 3,035
Muscle hypotonia 8 | 571
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
ductal carcinoma in situ 8 | 1,745
non-small cell lung cancer 8 | 2,890
ulcerative colitis 8 | 1,819
Breast cancer 7 | 3,578
Intellectual disability 7 | 1,016
aldosterone-producing adenoma 7 | 665
astrocytoma 7 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non primary Sjogren syndrome sicca 7 | 891
pancreatic cancer 7 | 2,398
subependymal giant cell astrocytoma 7 | 2,287
Alzheimer's disease 6 | 658
Dull intelligence 6 | 645
Kidney cancer 6 | 2,613
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Obesity 6 | 678
Poor school performance 6 | 645
Schizophrenia 6 | 1,160
breast carcinoma 6 | 1,638
Anemia 5 | 365
Atopic dermatitis 5 | 952
Carcinoma, Hepatocellular 5 | 228
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Hypoglycemia 5 | 152
Liver Cirrhosis, Experimental 5 | 769
Liver carcinoma 5 | 240
Mental and motor retardation 5 | 608
Neoplasm Invasiveness 5 | 161
Small head 5 | 374
adrenocortical carcinoma 5 | 1,428
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
medulloblastoma 5 | 720
nephrosclerosis 5 | 333
pituitary cancer 5 | 1,972
Cerebellar Ataxia 4 | 304
Cerebral atrophy 4 | 178
Cholestasis 4 | 155
Failure to gain weight 4 | 365
Heart failure 4 | 162
Hypertension 4 | 396
Infantile onset 4 | 238
Nystagmus 4 | 317
Parkinson's disease 4 | 392
Pediatric failure to thrive 4 | 365
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
posterior fossa group B ependymoma 4 | 416
Bipolar Disorder 3 | 666
Rheumatoid arthritis 3 | 1,191
chronic rhinosinusitis 3 | 512
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 63 | 18,159
Blood and immune system 62 | 16,909
Digestive Tract 61 | 17,369
Female tissues 61 | 17,400
Male tissues 61 | 17,142
Skin and soft tissues 61 | 17,230
Liver and Pancreas 60 | 16,750
Nervous System 60 | 16,725
Urinary Tract 60 | 16,678
Respiratory system 59 | 16,393
Cardiovascular System 58 | 15,192

Target Family

Enzyme 50 | 4,145
Kinase 7 | 634
Non-IDG 7 | 12,091

PANTHER Protein Class (0)

lyase 64 | 64
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
S-adenosylmethionine decarboxylase proenzyme AMD1 Tchem Enzyme -3.21826 1586.8 141
Deoxyribose-phosphate aldolase DERA Tbio Enzyme -2.21374 155.0 69
Ketimine reductase mu-crystallin CRYM Tbio Enzyme -1.70644 52.5 199
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
Hydroxymethylglutaryl-CoA synthase, cytoplasmic HMGCS1 Tchem Enzyme -1.67608 43.7 137
Adipocyte plasma membrane-associated protein APMAP Tbio Non-IDG -0.99483 11.3 155
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Hydroxymethylglutaryl-CoA synthase, mitochondrial HMGCS2 Tbio Enzyme -1.74279 54.0 126
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131