Development Level

Tbio 128 | 11,445
Tdark 40 | 6,588
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased vertical activity 7 | 208
preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
decreased body length 4 | 101
decreased total body fat amoun... 4 | 207
enlarged heart 4 | 210
abnormal eye morphology 3 | 68
decreased bone mineral content 3 | 151
decreased grip strength 3 | 116
improved glucose tolerance 3 | 79
increased total body fat amoun... 3 | 134
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating serum al... 2 | 82
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
persistence of hyaloid vascula... 2 | 33
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal liver morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal male genitalia morpho... 1 | 3
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
absent testes 1 | 6
cataract 1 | 92
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged lymph nodes 1 | 37
fusion of vertebral arches 1 | 7
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating lipase l... 1 | 3
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
male infertility 1 | 123
polysyndactyly 1 | 2
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
short tibia 1 | 97
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 137 | 11,493
ovarian cancer 81 | 8,520
psoriasis 75 | 6,694
glioblastoma 68 | 5,792
medulloblastoma, large-cell 64 | 6,241
osteosarcoma 59 | 7,950
atypical teratoid / rhabdoid tumor 56 | 5,112
Kidney cancer 54 | 2,613
ependymoma 54 | 4,679
lung cancer 52 | 4,740
Breast cancer 50 | 3,578
Astrocytoma, Pilocytic 48 | 3,081
invasive ductal carcinoma 42 | 2,951
adult high grade glioma 41 | 3,801
group 3 medulloblastoma 40 | 4,104
lung carcinoma 38 | 2,843
pancreatic cancer 37 | 2,398
interstitial cystitis 36 | 2,312
non-small cell lung cancer 34 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
lung adenocarcinoma 32 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
oligodendroglioma 31 | 2,850
primitive neuroectodermal tumor 30 | 3,035
malignant mesothelioma 29 | 3,232
pituitary cancer 29 | 1,972
Autosomal recessive predisposition 28 | 1,442
adrenocortical carcinoma 28 | 1,428
astrocytic glioma 28 | 2,597
cystic fibrosis 28 | 1,696
breast carcinoma 25 | 1,638
ductal carcinoma in situ 25 | 1,745
colon cancer 22 | 1,478
group 4 medulloblastoma 20 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
primary pancreatic ductal adenocarcinoma 19 | 1,109
subependymal giant cell astrocytoma 19 | 2,287
Liver cancer 16 | 604
Schizophrenia 16 | 1,160
gastric carcinoma 16 | 807
ulcerative colitis 16 | 1,819
Melanoma 15 | 711
Myopia 15 | 176
Skin cancer 15 | 469
pediatric high grade glioma 15 | 1,064
nasopharyngeal carcinoma 13 | 1,058
Atopic dermatitis 12 | 952
Cancer 12 | 2,499
Cataract 12 | 297
Duchenne muscular dystrophy 12 | 601
Endometriosis 12 | 540
Intellectual disability 12 | 1,016
cutaneous lupus erythematosus 12 | 1,057
tuberculosis 12 | 2,010
Acquired metabolic disease 11 | 336
Pick disease 11 | 1,894
active ulcerative colitis 11 | 764
fibroadenoma 11 | 559
medulloblastoma 11 | 720
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
juvenile dermatomyositis 10 | 1,187
posterior fossa group A ependymoma 10 | 468
Lens Opacities 9 | 231
Osteoarthritis 9 | 184
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
atypical teratoid/rhabdoid tumor 9 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
sonic hedgehog group medulloblastoma 9 | 467
Cryptorchidism 8 | 296
Hypoplastic mandible condyle 8 | 275
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Weill-Marchesani syndrome 8 | 14
active Crohn's disease 8 | 922
posterior fossa group B ependymoma 8 | 416
Endometrial cancer 7 | 311
Muscle hypotonia 7 | 571
Rheumatoid arthritis 7 | 1,191
Short stature 7 | 531
diabetes mellitus 7 | 1,728
Cleft Palate 6 | 271
Cognitive delay 6 | 608
Down syndrome 6 | 499
Glaucoma 6 | 239
Global developmental delay 6 | 608
Hydrolethalus syndrome 6 | 128
Mental and motor retardation 6 | 608
Nystagmus 6 | 317
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
aldosterone-producing adenoma 6 | 665
non diabetic and post-ischemic heart failure 6 | 200
non primary Sjogren syndrome sicca 6 | 891
urothelial carcinoma 6 | 318

Tissue

Endocrine System 170 | 18,159
Female tissues 167 | 17,400
Nervous System 164 | 16,725
Digestive Tract 163 | 17,369
Male tissues 162 | 17,142
Skin and soft tissues 162 | 17,230
Liver and Pancreas 158 | 16,750
Blood and immune system 155 | 16,909
Urinary Tract 155 | 16,678
Respiratory system 154 | 16,393
Cardiovascular System 143 | 15,192

Target Family

Non-IDG 142 | 12,091
Enzyme 26 | 4,145
GPCR 7 | 408

PANTHER Protein Class (0)

extracellular matrix protein 175 | 175
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spondin-2 SPON2 Tbio Non-IDG -1.73555 56.2 210
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Trophoblast glycoprotein TPBG Tbio Non-IDG -2.10560 136.9 206
Stonin-1 STON1-GTF2A1L Tbio Non-IDG -1.56384 21.8 68
A disintegrin and metalloproteinase with thrombospondin motifs 14 ADAMTS14 Tbio Enzyme -0.89572 7.58 29
Hyaluronan and proteoglycan link protein 4 HAPLN4 Tbio Non-IDG -0.76903 6.57 156
Tomoregulin-2 TMEFF2 Tbio Non-IDG -1.87758 86.0 194