Development Level

Tbio 147 | 10,625
Tdark 35 | 7,003
Tchem 15 | 1,890
Tclin 12 | 602

Collection

Eligible non-olfactory GPCR Proteins 20 | 143

IMPC Term

decreased bone mineral content 5 | 157
increased grip strength 5 | 83
preweaning lethality, complete... 5 | 633
decreased body length 3 | 108
decreased bone mineral density 3 | 126
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
decreased B cell number 2 | 30
decreased Ly6C low monocyte nu... 2 | 23
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased grip strength 2 | 123
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased monocyte cell number 2 | 28
enlarged heart 2 | 111
impaired glucose tolerance 2 | 52
increased NK cell number 2 | 19
increased leukocyte cell numbe... 2 | 37
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal eye anterior chamber ... 1 | 3
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 17
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased KLRG1-positive T-hel... 1 | 2
decreased Ly6C high monocyte n... 1 | 18
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating serum al... 1 | 79
decreased gamma-delta T cell n... 1 | 18
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged epididymis 1 | 27
female infertility 1 | 34
hydroencephaly 1 | 6
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased gamma-delta T cell n... 1 | 16
increased granulocyte number 1 | 8
increased lymphocyte cell numb... 1 | 9
increased mature B cell number 1 | 12
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased total body fat amoun... 1 | 57
pale yolk sac 1 | 12
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened PR interval 1 | 5

Disease

psoriasis 96 | 6,685
osteosarcoma 84 | 7,933
ovarian cancer 73 | 8,484
lung cancer 68 | 4,466
glioblastoma 67 | 5,572
medulloblastoma, large-cell 63 | 6,234
lung carcinoma 60 | 2,844
interstitial cystitis 51 | 2,299
pilocytic astrocytoma 49 | 3,086
atypical teratoid / rhabdoid tumor 46 | 4,369
lung adenocarcinoma 45 | 2,713
invasive ductal carcinoma 43 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
non-small cell lung cancer 40 | 2,798
subependymal giant cell astrocytoma 40 | 2,287
ulcerative colitis 39 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
Breast cancer 35 | 3,094
cutaneous lupus erythematosus 35 | 1,056
pediatric high grade glioma 34 | 2,712
Cancer 33 | 2,346
diabetes mellitus 33 | 1,663
posterior fossa group A ependymoma 33 | 1,511
adult high grade glioma 32 | 2,148
malignant mesothelioma 32 | 3,162
breast carcinoma 31 | 1,614
cystic fibrosis 31 | 1,665
tuberculosis 31 | 1,557
pancreatic cancer 29 | 2,300
oligodendroglioma 28 | 2,849
pituitary cancer 26 | 1,972
astrocytoma 25 | 1,493
primary Sjogren syndrome 25 | 789
ependymoma 24 | 2,514
Multiple Sclerosis 23 | 498
active Crohn's disease 21 | 918
astrocytic glioma 21 | 2,241
ductal carcinoma in situ 21 | 1,745
juvenile dermatomyositis 20 | 1,189
primitive neuroectodermal tumor 20 | 3,031
group 4 medulloblastoma 19 | 1,875
adrenocortical carcinoma 18 | 1,427
Rheumatoid Arthritis 17 | 1,160
medulloblastoma 17 | 1,524
primary pancreatic ductal adenocarcinoma 17 | 1,271
Carcinoma 16 | 2,147
esophageal adenocarcinoma 16 | 737
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
Atopic dermatitis 15 | 944
sonic hedgehog group medulloblastoma 15 | 1,482
group 3 medulloblastoma 14 | 2,254
Down syndrome 13 | 548
Hypersensitivity reaction type II disease 13 | 235
Multiple myeloma 13 | 1,327
colon cancer 13 | 1,475
nasopharyngeal carcinoma 13 | 1,056
atypical teratoid/rhabdoid tumor 12 | 1,095
posterior fossa group B ependymoma 12 | 1,530
Waldenstrons macroglobulinemia 11 | 765
dermatomyositis 11 | 933
mucosa-associated lymphoid tissue lymphoma 11 | 480
Asthma 10 | 349
Duchenne muscular dystrophy 10 | 602
IGA Glomerulonephritis 10 | 454
Pick disease 10 | 1,893
Endometriosis 9 | 535
active ulcerative colitis 9 | 477
chronic rhinosinusitis 9 | 512
head and neck cancer and chronic obstructive pulmonary disease 9 | 237
non-small cell lung carcinoma 9 | 413
tuberculosis and treatment for 3 months 9 | 327
Ankylosing spondylitis 8 | 138
Coronary artery disease 8 | 240
Hepatitis B 8 | 103
Liver disease 8 | 219
aldosterone-producing adenoma 8 | 664
chronic lymphosyte leukemia 8 | 232
spina bifida 8 | 1,064
Anemia 7 | 252
Celiac disease 7 | 112
Hypertension 7 | 287
Influenza 7 | 142
Kidney disease 7 | 396
Type 1 diabetes mellitus 7 | 101
gastric carcinoma 7 | 832
glioblastoma multiforme 7 | 347
periodontitis 7 | 269
tuberculosis and treatment for 6 months 7 | 686
Chronic Lymphocytic Leukemia 6 | 242
Narcolepsy 6 | 58
Obesity 6 | 616
Osteoporosis 6 | 257
Polycystic Ovary Syndrome 6 | 332
limb girdle muscular dystrophy 2I 6 | 56
nephrosclerosis 6 | 329
non primary Sjogren syndrome sicca 6 | 840
pancreatic carcinoma 6 | 567
systemic lupus erythematosus 6 | 156
urothelial carcinoma 6 | 318

Tissue

Digestive Tract 199 | 18,473
Female tissues 199 | 18,647
Blood and immune system 198 | 17,995
Endocrine System 198 | 18,512
Liver and Pancreas 198 | 18,136
Nervous System 198 | 18,561
Urinary Tract 197 | 18,444
Male tissues 194 | 17,969
Respiratory system 194 | 17,484
Cardiovascular System 193 | 17,958
Skin and soft tissues 193 | 18,115

Target Family

Non-IDG 151 | 11,971
GPCR 44 | 406
Enzyme 14 | 4,146

PANTHER Protein Class (0)

defense/immunity protein 209 | 209
transcription factor 1,533 | 1,533
nucleic acid binding 1,330 | 1,330
transferase 873 | 873
signaling molecule 820 | 820
transporter 767 | 767
enzyme modulator 713 | 713
hydrolase 631 | 631
cytoskeletal protein 608 | 608
receptor 550 | 550
cell adhesion molecule 502 | 502
oxidoreductase 404 | 404
transfer/carrier protein 308 | 308
ligase 291 | 291
membrane traffic protein 285 | 285
extracellular matrix protein 262 | 262
chaperone 163 | 163
isomerase 152 | 152
calcium-binding protein 149 | 149
cell junction protein 129 | 129
lyase 109 | 109
transmembrane receptor regulat... 68 | 68
surfactant 53 | 53
structural protein 42 | 42
storage protein 18 | 18
viral protein 13 | 13

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
HEAT repeat-containing protein 6 HEATR6 Tdark Non-IDG -1.48236 11.6 38
Interferon lambda receptor 1 IFNLR1 Tchem Non-IDG -1.48464 33.1 128
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
Zinc finger RNA-binding protein 2 ZFR2 Tdark Non-IDG -0.02511 0.87 5
Interleukin-10 receptor subunit beta IL10RB Tbio Non-IDG -1.82576 55.5 177
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.82506 66.9 35
Endoribonuclease LACTB2 LACTB2 Tbio Enzyme -0.15635 1.90 96
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.92696 10.7 107