Development Level

Tbio 399 | 10,625
Tdark 167 | 7,003
Tchem 33 | 1,890
Tclin 9 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 28 | 633
preweaning lethality, incomple... 16 | 260
increased lean body mass 9 | 107
increased or absent threshold ... 9 | 128
abnormal behavior 8 | 226
abnormal bone structure 8 | 131
decreased body weight 8 | 174
decreased circulating glucose ... 8 | 121
decreased total body fat amoun... 8 | 186
decreased bone mineral content 7 | 157
decreased circulating choleste... 7 | 85
decreased circulating insulin ... 7 | 75
abnormal embryo size 6 | 112
abnormal lens morphology 6 | 73
abnormal sleep behavior 6 | 63
decreased bone mineral density 6 | 126
decreased circulating serum al... 6 | 79
embryonic lethality prior to t... 6 | 187
hyperactivity 6 | 108
increased circulating chloride... 6 | 43
decreased circulating HDL chol... 5 | 77
decreased circulating total pr... 5 | 41
decreased lean body mass 5 | 195
decreased mean corpuscular vol... 5 | 50
improved glucose tolerance 5 | 56
increased circulating alkaline... 5 | 119
increased hematocrit 5 | 36
short tibia 5 | 82
abnormal behavioral response t... 4 | 52
cataract 4 | 26
decreased body length 4 | 108
decreased circulating free fat... 4 | 39
decreased rib number 4 | 59
increased bone mineral content 4 | 92
increased fasted circulating g... 4 | 68
increased grip strength 4 | 83
increased heart weight 4 | 37
increased mean corpuscular hem... 4 | 93
increased mean corpuscular vol... 4 | 91
increased rib number 4 | 41
abnormal bone mineralization 3 | 55
abnormal retina morphology 3 | 100
abnormal skin coloration 3 | 18
absent pinna reflex 3 | 21
decreased blood urea nitrogen ... 3 | 31
decreased circulating alanine ... 3 | 53
decreased circulating calcium ... 3 | 33
decreased circulating fructosa... 3 | 31
decreased circulating potassiu... 3 | 17
decreased circulating triglyce... 3 | 83
hypoactivity 3 | 89
increased body weight 3 | 42
increased circulating HDL chol... 3 | 63
increased circulating creatini... 3 | 29
increased circulating glucose ... 3 | 16
increased circulating phosphat... 3 | 24
increased circulating sodium l... 3 | 71
increased exploration in new e... 3 | 56
male infertility 3 | 62
prenatal lethality prior to he... 3 | 64
abnormal cranium morphology 2 | 32
abnormal digit morphology 2 | 13
abnormal eye morphology 2 | 38
abnormal joint morphology 2 | 14
abnormal locomotor activation 2 | 26
abnormal maxilla morphology 2 | 16
abnormal optic disc morphology 2 | 10
abnormal retinal pigmentation 2 | 61
abnormal tail morphology 2 | 17
abnormal thoracic vertebrae mo... 2 | 16
abnormal vertebrae morphology 2 | 14
abnormal vocalization 2 | 21
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating alkaline... 2 | 41
decreased circulating aspartat... 2 | 27
decreased circulating chloride... 2 | 32
decreased circulating iron lev... 2 | 25
decreased grip strength 2 | 123
decreased lumbar vertebrae num... 2 | 62
decreased startle reflex 2 | 48
embryonic lethality prior to o... 2 | 148
fusion of vertebral arches 2 | 7
impaired glucose tolerance 2 | 52
impaired righting response 2 | 19
increased circulating choleste... 2 | 53
increased circulating iron lev... 2 | 25
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 25
increased red blood cell distr... 2 | 21
shortened ST segment 2 | 9
thrombocytopenia 2 | 46
vertebral fusion 2 | 23
abnormal embryo turning 1 | 15
abnormal tail movements 1 | 12
decreased circulating sodium l... 1 | 18
decreased mean corpuscular hem... 1 | 34
embryonic growth retardation 1 | 28
female infertility 1 | 34

Disease

ovarian cancer 277 | 8,484
psoriasis 269 | 6,685
osteosarcoma 252 | 7,933
glioblastoma 237 | 5,572
medulloblastoma, large-cell 236 | 6,234
atypical teratoid / rhabdoid tumor 176 | 4,369
lung cancer 176 | 4,466
primitive neuroectodermal tumor 152 | 3,031
pilocytic astrocytoma 150 | 3,086
malignant mesothelioma 141 | 3,162
pediatric high grade glioma 140 | 2,712
Breast cancer 137 | 3,094
non-small cell lung cancer 134 | 2,798
oligodendroglioma 133 | 2,849
intraductal papillary-mucinous carcinoma (IPMC) 129 | 2,988
invasive ductal carcinoma 129 | 2,950
pancreatic cancer 116 | 2,300
lung carcinoma 115 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 113 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 112 | 3,289
lung adenocarcinoma 111 | 2,713
ependymoma 108 | 2,514
subependymal giant cell astrocytoma 102 | 2,287
Carcinoma 97 | 2,147
colon cancer 92 | 1,475
breast carcinoma 90 | 1,614
Pick disease 83 | 1,893
ductal carcinoma in situ 83 | 1,745
interstitial cystitis 80 | 2,299
astrocytic glioma 78 | 2,241
group 3 medulloblastoma 74 | 2,254
posterior fossa group B ependymoma 74 | 1,530
nasopharyngeal carcinoma 72 | 1,056
pituitary cancer 72 | 1,972
cystic fibrosis 70 | 1,665
primary pancreatic ductal adenocarcinoma 70 | 1,271
sonic hedgehog group medulloblastoma 68 | 1,482
adult high grade glioma 67 | 2,148
spina bifida 63 | 1,064
adrenocortical carcinoma 62 | 1,427
astrocytoma 61 | 1,493
posterior fossa group A ependymoma 61 | 1,511
group 4 medulloblastoma 60 | 1,875
acute quadriplegic myopathy 56 | 1,157
ulcerative colitis 56 | 2,087
Cancer 55 | 2,346
juvenile dermatomyositis 52 | 1,189
Atopic dermatitis 51 | 944
atypical teratoid/rhabdoid tumor 51 | 1,095
diabetes mellitus 49 | 1,663
medulloblastoma 49 | 1,524
dermatomyositis 47 | 933
tuberculosis 47 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 45 | 1,795
Duchenne muscular dystrophy 44 | 602
cutaneous lupus erythematosus 44 | 1,056
chronic rhinosinusitis 39 | 512
Multiple myeloma 38 | 1,327
Rheumatoid Arthritis 37 | 1,160
esophageal adenocarcinoma 37 | 737
progressive supranuclear palsy 36 | 674
Down syndrome 34 | 548
gastric carcinoma 34 | 832
autosomal dominant Emery-Dreifuss muscular dystrophy 31 | 499
Alzheimer's disease 29 | 644
Endometriosis 28 | 535
Amyotrophic Lateral Sclerosis 27 | 431
fibroadenoma 26 | 557
primary Sjogren syndrome 25 | 789
pancreatic carcinoma 24 | 567
active Crohn's disease 23 | 918
acute myeloid leukemia 23 | 780
Neurodegenerative disease 22 | 383
active ulcerative colitis 22 | 477
hereditary spastic paraplegia 22 | 313
tuberculosis and treatment for 6 months 22 | 686
Neuropathy 21 | 210
Waldenstrons macroglobulinemia 21 | 765
aldosterone-producing adenoma 21 | 664
gastric cancer 21 | 430
mucosa-associated lymphoid tissue lymphoma 21 | 480
Cardiomyopathy 20 | 110
IGA Glomerulonephritis 20 | 454
non primary Sjogren syndrome sicca 20 | 840
Intellectual disability 19 | 573
Becker muscular dystrophy 18 | 187
Primary ciliary dyskinesia 18 | 73
Polycystic Ovary Syndrome 16 | 332
Microcephaly 15 | 149
Parkinson's disease 15 | 364
hepatocellular carcinoma 15 | 532
inflammatory breast cancer 15 | 404
non-small cell lung carcinoma 15 | 413
Obesity 14 | 616
Prostatic Neoplasms 13 | 471
periodontitis 13 | 269
Dilated cardiomyopathy 12 | 50
Epilepsy 12 | 346
Lissencephaly 12 | 61
Situs Inversus 12 | 48

Tissue

Digestive Tract 587 | 18,473
Endocrine System 587 | 18,512
Female tissues 587 | 18,647
Nervous System 587 | 18,561
Urinary Tract 586 | 18,444
Liver and Pancreas 585 | 18,136
Cardiovascular System 584 | 17,958
Blood and immune system 583 | 17,995
Male tissues 583 | 17,969
Skin and soft tissues 577 | 18,115
Respiratory system 570 | 17,484

Target Family

Non-IDG 559 | 11,971
Enzyme 41 | 4,146
Kinase 6 | 634
Transcription Factor 2 | 1,400

PANTHER Protein Class (0)

cytoskeletal protein 608 | 608
transcription factor 1,533 | 1,533
nucleic acid binding 1,330 | 1,330
transferase 873 | 873
signaling molecule 820 | 820
transporter 767 | 767
enzyme modulator 713 | 713
hydrolase 631 | 631
receptor 550 | 550
cell adhesion molecule 502 | 502
oxidoreductase 404 | 404
transfer/carrier protein 308 | 308
ligase 291 | 291
membrane traffic protein 285 | 285
extracellular matrix protein 262 | 262
defense/immunity protein 209 | 209
chaperone 163 | 163
isomerase 152 | 152
calcium-binding protein 149 | 149
cell junction protein 129 | 129
lyase 109 | 109
transmembrane receptor regulat... 68 | 68
surfactant 53 | 53
structural protein 42 | 42
storage protein 18 | 18
viral protein 13 | 13

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Microtubule-associated protein RP/EB family member 3 MAPRE3 Tbio Non-IDG -2.14681 132.5 161
Wiskott-Aldrich syndrome protein family member 3 WASF3 Tbio Non-IDG -2.43045 280.1 123
Keratin, type II cytoskeletal 3 KRT3 Tbio Non-IDG -2.12849 126.8 100
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Keratin, type II cytoskeletal 74 KRT74 Tbio Non-IDG -2.22050 159.7 35
Filensin BFSP1 Tbio Non-IDG -2.08549 124.5 154
Actin-related protein 2 ACTR2 Tchem Non-IDG -1.84526 72.5 184
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8