Development Level

Tbio 55 | 11,445
Tdark 24 | 6,588
Tchem 10 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
edema 1 | 59
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
increased grip strength 1 | 41
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 46 | 11,493
ovarian cancer 44 | 8,520
medulloblastoma, large-cell 38 | 6,241
osteosarcoma 36 | 7,950
lung cancer 32 | 4,740
psoriasis 30 | 6,694
atypical teratoid / rhabdoid tumor 28 | 5,112
glioblastoma 28 | 5,792
ependymoma 27 | 4,679
adult high grade glioma 26 | 3,801
Breast cancer 23 | 3,578
group 3 medulloblastoma 23 | 4,104
Multiple myeloma 21 | 1,332
oligodendroglioma 20 | 2,850
astrocytic glioma 19 | 2,597
Waldenstrons macroglobulinemia 15 | 765
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
primitive neuroectodermal tumor 15 | 3,035
Astrocytoma, Pilocytic 14 | 3,081
Cancer 14 | 2,499
acute quadriplegic myopathy 14 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
subependymal giant cell astrocytoma 12 | 2,287
dermatomyositis 11 | 966
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Parkinson's disease 10 | 392
Pick disease 10 | 1,894
colon cancer 10 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
diabetes mellitus 9 | 1,728
malignant mesothelioma 9 | 3,232
primary pancreatic ductal adenocarcinoma 9 | 1,109
Autosomal recessive predisposition 7 | 1,442
Neurodegenerative disease 7 | 414
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pancreatic carcinoma 7 | 562
ulcerative colitis 7 | 1,819
Dementia 6 | 175
Duchenne muscular dystrophy 6 | 601
Epilepsy 6 | 792
HIV Infections 6 | 102
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
Intellectual disability 5 | 1,016
Kidney cancer 5 | 2,613
Seizures 5 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
Adenocarcinoma of lung 4 | 142
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Disease Models, Animal 4 | 155
Dysarthria 4 | 192
Gonadoblastoma 4 | 34
Multiple Sclerosis 4 | 540
Parkinsonian Disorders 4 | 56
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
atypical teratoid/rhabdoid tumor 4 | 357
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 547
hereditary spastic paraplegia 4 | 318
non primary Sjogren syndrome sicca 4 | 891
Amyotrophic lateral sclerosis 3 | 451
Breast Neoplasms 3 | 445
Candidiasis 3 | 55
Cardiomyopathies 3 | 110
Degenerative polyarthritis 3 | 115
Depressive disorder 3 | 409
Dystonia 3 | 164
Epidermolysis bullosa acquisita 3 | 10
Frontal bossing 3 | 157
Henoch-Schoenlein purpura 3 | 12
Liver Cirrhosis, Experimental 3 | 769
Malaria 3 | 160
Male infertility 3 | 206
Mammary Neoplasms 3 | 425
Multiple system atrophy 3 | 29
Muscle Rigidity 3 | 49
Muscle hypotonia 3 | 571
Ollier disease 3 | 18
Orbital separation excessive 3 | 244
Osteoporosis 3 | 363
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
hypoparathyroidism-retardation-dysmorphism syndrome 3 | 7
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409

Tissue

Endocrine System 80 | 18,159
Digestive Tract 75 | 17,369
Liver and Pancreas 75 | 16,750
Skin and soft tissues 75 | 17,230
Blood and immune system 74 | 16,909
Nervous System 73 | 16,725
Female tissues 72 | 17,400
Male tissues 72 | 17,142
Respiratory system 72 | 16,393
Urinary Tract 72 | 16,678
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 76 | 12,091
Enzyme 12 | 4,145
Kinase 1 | 634

PANTHER Protein Class (0)

chaperone 89 | 89
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 Tchem Enzyme -1.80418 63.8 91
Putative protein PTGES3L PTGES3L Tdark Non-IDG 0.85 0.09 0
Torsin-4A TOR4A Tdark Non-IDG 0.77 0.09 17
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.26984 173.7 468
Testis-specific Y-encoded-like protein 5 TSPYL5 Tbio Non-IDG -0.97896 9.36 76
Testis-specific Y-encoded protein 1 TSPY3 Tbio Non-IDG -2.00153 98.7 136
Testis-specific Y-encoded-like protein 4 TSPYL4 Tdark Non-IDG -0.11115 0.87 119
Gamma-synuclein SNCG Tbio Non-IDG -2.24895 187.3 294