Development Level

Tbio 102 | 10,625
Tdark 24 | 7,003
Tchem 3 | 1,890

IMPC Term

preweaning lethality, complete... 6 | 633
decreased lean body mass 5 | 195
embryonic lethality prior to t... 4 | 187
abnormal bone structure 3 | 131
abnormal sleep behavior 3 | 63
decreased bone mineral content 3 | 157
decreased total body fat amoun... 3 | 186
increased or absent threshold ... 3 | 128
prenatal lethality prior to he... 3 | 64
abnormal behavior 2 | 226
abnormal behavioral response t... 2 | 52
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal placenta size 2 | 10
abnormal retina morphology 2 | 100
absent startle reflex 2 | 15
cardiovascular system phenotyp... 2 | 35
convulsive seizures 2 | 11
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating amylase ... 2 | 24
decreased circulating free fat... 2 | 39
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased startle reflex 2 | 48
enlarged heart 2 | 111
hemorrhage 2 | 12
hyperactivity 2 | 108
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 93
persistence of hyaloid vascula... 2 | 22
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal ear morphology 1 | 5
abnormal forebrain morphology 1 | 4
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal motor coordination/ b... 1 | 4
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal respiratory quotient 1 | 9
abnormal skin coloration 1 | 18
abnormal tail morphology 1 | 17
abnormal vocalization 1 | 21
absent heartbeat 1 | 6
absent pinna reflex 1 | 21
anophthalmia 1 | 20
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased Ly6C low monocyte nu... 1 | 23
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
edema 1 | 11
fused cornea and lens 1 | 4
fused phalanges 1 | 1
hydrometra 1 | 13
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating chloride... 1 | 43
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
short tibia 1 | 82
shortened PQ interval 1 | 6
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

ovarian cancer 58 | 8,484
osteosarcoma 56 | 7,933
psoriasis 51 | 6,685
Carcinoma 41 | 2,147
medulloblastoma, large-cell 39 | 6,234
non-small cell lung cancer 37 | 2,798
atypical teratoid / rhabdoid tumor 35 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
glioblastoma 31 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,289
interstitial cystitis 29 | 2,299
lung adenocarcinoma 28 | 2,713
invasive ductal carcinoma 27 | 2,950
lung carcinoma 25 | 2,844
subependymal giant cell astrocytoma 25 | 2,287
Breast cancer 24 | 3,094
lung cancer 24 | 4,466
pilocytic astrocytoma 24 | 3,086
primitive neuroectodermal tumor 24 | 3,031
pituitary cancer 23 | 1,972
malignant mesothelioma 22 | 3,162
pancreatic cancer 22 | 2,300
ductal carcinoma in situ 21 | 1,745
pediatric high grade glioma 21 | 2,712
ulcerative colitis 20 | 2,087
ependymoma 18 | 2,514
adult high grade glioma 16 | 2,148
gastric carcinoma 16 | 832
oligodendroglioma 16 | 2,849
sonic hedgehog group medulloblastoma 16 | 1,482
spina bifida 15 | 1,064
Cancer 14 | 2,346
Nonsyndromic deafness 14 | 121
Sensorineural hearing loss 14 | 107
acute quadriplegic myopathy 14 | 1,157
breast carcinoma 14 | 1,614
cystic fibrosis 14 | 1,665
astrocytic glioma 13 | 2,241
medulloblastoma 13 | 1,524
posterior fossa group B ependymoma 12 | 1,530
primary pancreatic ductal adenocarcinoma 12 | 1,271
nasopharyngeal carcinoma 11 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Down syndrome 10 | 548
group 4 medulloblastoma 10 | 1,875
Oculodentodigital dysplasia 9 | 14
Pick disease 9 | 1,893
active Crohn's disease 9 | 918
astrocytoma 9 | 1,493
diabetes mellitus 9 | 1,663
Atopic dermatitis 8 | 944
Erythrokeratodermia variabilis 8 | 10
adrenocortical carcinoma 8 | 1,427
colon cancer 8 | 1,475
group 3 medulloblastoma 8 | 2,254
posterior fossa group A ependymoma 8 | 1,511
Prostatic Neoplasms 7 | 471
atypical teratoid/rhabdoid tumor 7 | 1,095
interstitial lung disease 7 | 291
juvenile dermatomyositis 7 | 1,189
tuberculosis 7 | 1,557
dermatomyositis 6 | 933
esophageal adenocarcinoma 6 | 737
Amyotrophic Lateral Sclerosis 5 | 431
Cardiomyopathy 5 | 110
Clouston syndrome 5 | 9
Hypertensive disease 5 | 193
Inflammatory bowel disease 5 | 142
Palmoplantar keratosis 5 | 36
Peripheral Neuropathy 5 | 303
acute myeloid leukemia 5 | 780
cutaneous lupus erythematosus 5 | 1,056
mucosa-associated lymphoid tissue lymphoma 5 | 480
non diabetic and post-ischemic heart failure 5 | 200
non primary Sjogren syndrome sicca 5 | 840
urothelial carcinoma 5 | 318
Cataract 4 | 104
Celiac disease 4 | 112
Cerebrovascular disease 4 | 231
Diarrhea 4 | 155
Distal arthrogryposis 4 | 45
Duchenne muscular dystrophy 4 | 602
Heart disease 4 | 279
Hodgkin's lymphoma, nodular sclerosis 4 | 24
Hypertension 4 | 287
Intellectual disability 4 | 573
Kidney disease 4 | 396
Multiple Sclerosis 4 | 498
Myopathy 4 | 128
Neuropathy 4 | 210
Ophthalmoplegia 4 | 18
Rheumatoid Arthritis 4 | 1,160
Usher syndrome 4 | 34
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
facioscapulohumeral dystrophy 4 | 286
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 3 months 4 | 327
Becker muscular dystrophy 3 | 187
chronic lymphosyte leukemia 3 | 232

Tissue

Female tissues 124 | 18,647
Endocrine System 123 | 18,512
Nervous System 123 | 18,561
Liver and Pancreas 121 | 18,136
Skin and soft tissues 121 | 18,115
Blood and immune system 120 | 17,995
Digestive Tract 120 | 18,473
Urinary Tract 120 | 18,444
Male tissues 119 | 17,969
Cardiovascular System 118 | 17,958
Respiratory system 116 | 17,484

Target Family

Non-IDG 120 | 11,971
Enzyme 6 | 4,146
Kinase 3 | 634

PANTHER Protein Class (0)

cell junction protein 129 | 129
transcription factor 1,533 | 1,533
nucleic acid binding 1,330 | 1,330
transferase 873 | 873
signaling molecule 820 | 820
transporter 767 | 767
enzyme modulator 713 | 713
hydrolase 631 | 631
cytoskeletal protein 608 | 608
receptor 550 | 550
cell adhesion molecule 502 | 502
oxidoreductase 404 | 404
transfer/carrier protein 308 | 308
ligase 291 | 291
membrane traffic protein 285 | 285
extracellular matrix protein 262 | 262
defense/immunity protein 209 | 209
chaperone 163 | 163
isomerase 152 | 152
calcium-binding protein 149 | 149
lyase 109 | 109
transmembrane receptor regulat... 68 | 68
surfactant 53 | 53
structural protein 42 | 42
storage protein 18 | 18
viral protein 13 | 13

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.77228 625.6 162
Claudin-3 CLDN3 Tbio Non-IDG -2.30333 205.5 260
Kin of IRRE-like protein 3 KIRREL3 Tbio Non-IDG -1.37511 25.5 78
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.55538 356.6 142
Gap junction gamma-1 protein GJC1 Tbio Non-IDG -2.26749 174.8 192
Myosin-3 MYH3 Tbio Non-IDG -1.66510 45.6 38
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.22681 169.2 210
Coiled-coil domain-containing protein 171 CCDC171 Tdark Non-IDG 0.27 0.42 40
Coiled-coil domain-containing protein 150 CCDC150 Tdark Non-IDG 0.00000 8