Development Level

Tbio 308 | 10,625
Tdark 138 | 7,003
Tchem 46 | 1,890
Tclin 10 | 602

Collection

GPCR: IDG Consortium (Targets) 1 | 127
Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

decreased total body fat amoun... 8 | 186
preweaning lethality, complete... 7 | 633
abnormal behavior 6 | 226
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
increased mean corpuscular hem... 5 | 93
abnormal gait 4 | 51
abnormal sleep behavior 4 | 63
decreased body length 4 | 108
decreased bone mineral density 4 | 126
decreased circulating serum al... 4 | 79
preweaning lethality, incomple... 4 | 260
tremors 4 | 34
abnormal coat-hair pigmentatio... 3 | 54
abnormal lens morphology 3 | 73
decreased NK T cell number 3 | 28
decreased body weight 3 | 174
decreased circulating glucose ... 3 | 121
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
decreased heart weight 3 | 44
decreased neutrophil cell numb... 3 | 37
increased hemoglobin content 3 | 45
short tibia 3 | 82
straub tail 3 | 26
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal eye morphology 2 | 38
abnormal locomotor activation 2 | 26
abnormal retina morphology 2 | 100
abnormal startle reflex 2 | 14
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 35
corneal opacity 2 | 25
decreased Ly6C high monocyte n... 2 | 18
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating iron lev... 2 | 25
decreased circulating total pr... 2 | 41
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular hem... 2 | 19
decreased monocyte cell number 2 | 28
decreased pulmonary respirator... 2 | 4
decreased vertical activity 2 | 22
edema 2 | 11
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
increased sacral vertebrae num... 2 | 62
increased vertical activity 2 | 18
prenatal lethality prior to he... 2 | 64
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal embryo turning 1 | 15
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal skin appearance 1 | 8
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 14
convulsive seizures 1 | 11
decreased alpha-beta T cell nu... 1 | 12
decreased basophil cell number 1 | 11
decreased cardiac muscle contr... 1 | 5
decreased circulating phosphat... 1 | 15
decreased hematocrit 1 | 25
decreased mean corpuscular vol... 1 | 50
dilated heart left ventricle 1 | 10
embryonic growth retardation 1 | 28
enlarged stomach 1 | 2
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating alanine ... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased mean corpuscular hem... 1 | 25
lethargy 1 | 5
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
shortened ST segment 1 | 9
small thymus 1 | 11
trunk curl 1 | 15

Disease

psoriasis 214 | 6,685
osteosarcoma 198 | 7,933
ovarian cancer 191 | 8,491
Carcinoma 162 | 2,147
glioblastoma 162 | 5,572
lung carcinoma 162 | 2,844
medulloblastoma, large-cell 156 | 6,234
lung cancer 136 | 4,473
atypical teratoid / rhabdoid tumor 125 | 4,369
pilocytic astrocytoma 123 | 3,086
invasive ductal carcinoma 120 | 2,950
lung adenocarcinoma 116 | 2,714
interstitial cystitis 113 | 2,299
non-small cell lung cancer 111 | 2,798
Breast cancer 109 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 107 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 103 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 101 | 3,289
Cancer 100 | 2,346
malignant mesothelioma 95 | 3,163
oligodendroglioma 93 | 2,849
ulcerative colitis 91 | 2,087
pediatric high grade glioma 90 | 2,712
pancreatic cancer 88 | 2,300
primitive neuroectodermal tumor 84 | 3,031
ductal carcinoma in situ 75 | 1,745
subependymal giant cell astrocytoma 74 | 2,287
pituitary cancer 71 | 1,972
group 4 medulloblastoma 68 | 1,875
adult high grade glioma 67 | 2,148
cystic fibrosis 64 | 1,670
ependymoma 64 | 2,514
posterior fossa group A ependymoma 63 | 1,511
colon cancer 60 | 1,475
tuberculosis 58 | 1,563
astrocytic glioma 57 | 2,241
cutaneous lupus erythematosus 55 | 1,056
group 3 medulloblastoma 55 | 2,254
breast carcinoma 50 | 1,614
primary pancreatic ductal adenocarcinoma 49 | 1,271
posterior fossa group B ependymoma 47 | 1,530
astrocytoma 44 | 1,493
sonic hedgehog group medulloblastoma 44 | 1,482
Pick disease 43 | 1,893
nasopharyngeal carcinoma 43 | 1,056
Rheumatoid Arthritis 41 | 1,170
primary Sjogren syndrome 41 | 788
Atopic dermatitis 40 | 944
adrenocortical carcinoma 39 | 1,427
gastric carcinoma 39 | 832
diabetes mellitus 38 | 1,663
esophageal adenocarcinoma 35 | 737
medulloblastoma 34 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,795
Duchenne muscular dystrophy 32 | 602
Multiple Sclerosis 32 | 498
mucosa-associated lymphoid tissue lymphoma 32 | 480
Asthma 30 | 349
atypical teratoid/rhabdoid tumor 30 | 1,095
dermatomyositis 28 | 966
juvenile dermatomyositis 28 | 1,189
non-small cell lung carcinoma 27 | 413
Autistic Disorder 26 | 320
Down syndrome 26 | 548
fibroadenoma 26 | 557
active Crohn's disease 25 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 499
Obesity 23 | 616
non primary Sjogren syndrome sicca 23 | 840
Alzheimer's disease 22 | 644
urothelial carcinoma 22 | 318
Hypersensitivity reaction type II disease 21 | 235
Kidney disease 20 | 397
interstitial lung disease 20 | 292
spina bifida 20 | 1,064
nephrosclerosis 19 | 329
pancreatic carcinoma 19 | 567
Atherosclerosis 18 | 275
Human immunodeficiency virus infectious disease 18 | 129
IGA Glomerulonephritis 18 | 454
Vascular disease 18 | 281
head and neck cancer 18 | 270
periodontitis 18 | 269
Anemia 17 | 252
Melanoma 17 | 261
Schizophrenia 17 | 503
Multiple myeloma 16 | 1,327
Thrombocytopenia 16 | 105
Intellectual disability 15 | 573
acute myeloid leukemia 15 | 785
acute quadriplegic myopathy 15 | 1,157
hepatocellular carcinoma 15 | 550
sarcoidosis 15 | 368
Age related macular degeneration 14 | 84
Endometriosis 14 | 535
Inflammatory bowel disease 14 | 142
Kidney cancer 14 | 121
Peripheral Neuropathy 14 | 303
chronic rhinosinusitis 14 | 512
non-inflammatory breast cancer 14 | 208

Tissue

Female tissues 492 | 18,646
Endocrine System 487 | 18,511
Nervous System 487 | 18,560
Digestive Tract 486 | 18,472
Male tissues 485 | 17,968
Urinary Tract 485 | 18,443
Liver and Pancreas 481 | 18,135
Blood and immune system 479 | 17,994
Skin and soft tissues 472 | 18,114
Cardiovascular System 471 | 17,957
Respiratory system 463 | 17,483

Target Family

Non-IDG 462 | 11,969
GPCR 26 | 408
Kinase 6 | 634
Enzyme 5 | 4,146
Ion Channel 2 | 341
Transcription Factor 1 | 1,400

PANTHER Protein Class (0)

cell adhesion molecule 502 | 502
transcription factor 1,533 | 1,533
nucleic acid binding 1,330 | 1,330
transferase 873 | 873
signaling molecule 820 | 820
transporter 767 | 767
enzyme modulator 713 | 713
hydrolase 631 | 631
cytoskeletal protein 608 | 608
receptor 550 | 550
oxidoreductase 404 | 404
transfer/carrier protein 308 | 308
ligase 291 | 291
membrane traffic protein 285 | 285
extracellular matrix protein 262 | 262
defense/immunity protein 209 | 209
chaperone 163 | 163
isomerase 152 | 152
calcium-binding protein 149 | 149
cell junction protein 129 | 129
lyase 109 | 109
transmembrane receptor regulat... 68 | 68
surfactant 53 | 53
structural protein 42 | 42
storage protein 18 | 18
viral protein 13 | 13

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Sialic acid-binding Ig-like lectin 12 SIGLEC12 Tbio Non-IDG -2.35522 224.6 122
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
Coiled-coil domain-containing protein 141 CCDC141 Tdark Non-IDG -0.61681 3.82 82
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.45436 257.8 324
Centrosomal protein of 41 kDa CEP41 Tdark Non-IDG -0.38839 3.35 44
Contactin-associated protein-like 3 CNTNAP3 Tdark Non-IDG -0.68943 0.00000 28
Trophinin TRO Tbio Non-IDG -1.91773 87.8 26
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.25305 16.3 98