Development Level

Tbio 76 | 11,445
Tdark 13 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 5 | 278
abnormal behavior 4 | 298
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
abnormal sleep behavior 3 | 70
embryonic lethality prior to o... 3 | 239
hyperactivity 3 | 148
abnormal behavioral response t... 2 | 66
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased circulating phosphat... 2 | 26
abnormal allantois morphology 1 | 8
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal stomach morphology 1 | 10
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent pinna reflex 1 | 23
brachydactyly 1 | 19
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased anxiety-related resp... 1 | 2
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
long tibia 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
syndactyly 1 | 23
thin ventricular wall 1 | 24

Disease

Carcinoma 64 | 11,493
ovarian cancer 48 | 8,520
glioblastoma 46 | 5,792
medulloblastoma, large-cell 43 | 6,241
psoriasis 42 | 6,694
osteosarcoma 38 | 7,950
atypical teratoid / rhabdoid tumor 36 | 5,112
ependymoma 33 | 4,679
pancreatic cancer 33 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
Astrocytoma, Pilocytic 27 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
lung cancer 27 | 4,740
invasive ductal carcinoma 26 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
adult high grade glioma 24 | 3,801
primary pancreatic ductal adenocarcinoma 24 | 1,109
primitive neuroectodermal tumor 24 | 3,035
subependymal giant cell astrocytoma 24 | 2,287
Breast cancer 23 | 3,578
group 3 medulloblastoma 23 | 4,104
lung carcinoma 21 | 2,843
non-small cell lung cancer 20 | 2,890
malignant mesothelioma 19 | 3,232
spina bifida 19 | 1,074
oligodendroglioma 17 | 2,850
colon cancer 16 | 1,478
interstitial cystitis 16 | 2,312
acute quadriplegic myopathy 15 | 1,158
breast carcinoma 15 | 1,638
ductal carcinoma in situ 15 | 1,745
lung adenocarcinoma 15 | 2,716
tuberculosis 15 | 2,010
Rheumatoid arthritis 14 | 1,191
Pick disease 13 | 1,894
astrocytoma 13 | 1,146
group 4 medulloblastoma 13 | 1,855
ulcerative colitis 13 | 1,819
adrenocortical carcinoma 12 | 1,428
cystic fibrosis 12 | 1,696
pediatric high grade glioma 12 | 1,064
pituitary cancer 12 | 1,972
Cancer 11 | 2,499
Duchenne muscular dystrophy 11 | 601
diabetes mellitus 11 | 1,728
astrocytic glioma 10 | 2,597
dermatomyositis 10 | 966
juvenile dermatomyositis 10 | 1,187
Alzheimer's disease 9 | 658
Atopic dermatitis 9 | 952
Bipolar Disorder 9 | 666
Schizophrenia 9 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
esophageal adenocarcinoma 9 | 737
Kidney cancer 8 | 2,613
Liver Cirrhosis, Experimental 8 | 769
aldosterone-producing adenoma 8 | 665
gastric carcinoma 8 | 807
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Down syndrome 7 | 499
Multiple myeloma 7 | 1,332
pancreatic carcinoma 7 | 562
active ulcerative colitis 6 | 764
nasopharyngeal carcinoma 6 | 1,058
primary Sjogren syndrome 6 | 735
Amyotrophic lateral sclerosis 5 | 451
Endometriosis 5 | 540
Obesity 5 | 678
Osteoporosis 5 | 363
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
gastric cancer 5 | 459
Becker muscular dystrophy 4 | 191
Esophageal Squamous Cell Carcinoma 4 | 77
Hypertension 4 | 396
Nemaline myopathy 4 | 17
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Squamous cell carcinoma of esophagus 4 | 77
Waldenstrons macroglobulinemia 4 | 765
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
fibroadenoma 4 | 559
hereditary spastic paraplegia 4 | 318
interstitial lung disease 4 | 298
Attention deficit hyperactivity disorder 3 | 278
Broad flat nasal bridge 3 | 236
Carcinoma, Hepatocellular 3 | 228
Coronary artery disease 3 | 268
Kidney Failure 3 | 111
Liver carcinoma 3 | 240
Major Depressive Disorder 3 | 301
Nasal bridge wide 3 | 236
Polycystic ovary syndrome 3 | 360
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
nephrosclerosis 3 | 333
periodontitis 3 | 293
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Male tissues 89 | 17,142
Skin and soft tissues 89 | 17,230
Blood and immune system 88 | 16,909
Digestive Tract 88 | 17,369
Respiratory system 87 | 16,393
Urinary Tract 87 | 16,678
Nervous System 86 | 16,725
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 79 | 12,091
Transcription Factor 8 | 1,400
Enzyme 3 | 4,145

PANTHER Protein Class (2)

non-motor actin binding protei... 90 | 90
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leiomodin-3 LMOD3 Tbio Non-IDG -1.00928 10.3 27
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Transgelin-3 TAGLN3 Tbio Non-IDG -1.54779 34.2 126
Leiomodin-2 LMOD2 Tbio Non-IDG -0.89671 9.37 55
PDZ and LIM domain protein 4 PDLIM4 Tbio Non-IDG -2.02708 99.1 145
Adseverin SCIN Tbio Non-IDG -1.90989 89.8 72
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.90666 762.6 254
Calponin-1 CNN1 Tbio Non-IDG -2.21051 158.8 466
Espin-like protein ESPNL Tdark Non-IDG 0.04 0.97 65