Development Level

Tbio 39 | 11,445
Tdark 9 | 6,588
Tchem 7 | 1,598

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
embryonic lethality prior to o... 3 | 239
abnormal neural tube closure 2 | 46
female infertility 2 | 60
male infertility 2 | 123
pale yolk sac 2 | 25
pallor 2 | 34
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal pharyngeal arch morph... 1 | 8
abnormal placenta size 1 | 20
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
small kidney 1 | 16
small testis 1 | 58
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 31 | 8,520
Carcinoma 30 | 11,493
osteosarcoma 30 | 7,950
medulloblastoma, large-cell 25 | 6,241
lung cancer 21 | 4,740
psoriasis 21 | 6,694
Cancer 17 | 2,499
glioblastoma 17 | 5,792
group 3 medulloblastoma 17 | 4,104
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 15 | 2,890
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 14 | 4,679
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
lung adenocarcinoma 13 | 2,716
primitive neuroectodermal tumor 13 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
subependymal giant cell astrocytoma 10 | 2,287
breast carcinoma 9 | 1,638
oligodendroglioma 9 | 2,850
Pick disease 8 | 1,894
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
Astrocytoma, Pilocytic 7 | 3,081
Atopic dermatitis 7 | 952
Multiple myeloma 7 | 1,332
adrenocortical carcinoma 7 | 1,428
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
nasopharyngeal carcinoma 7 | 1,058
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
dermatomyositis 6 | 966
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
Duchenne muscular dystrophy 5 | 601
Schizophrenia 5 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
ulcerative colitis 5 | 1,819
Amyotrophic lateral sclerosis 4 | 451
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Endometriosis 4 | 540
Liver Cirrhosis, Experimental 4 | 769
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
Carcinoma, Hepatocellular 3 | 228
Glycogen storage disease 3 | 39
Liver carcinoma 3 | 240
Polycystic ovary syndrome 3 | 360
Type 2 diabetes mellitus 3 | 272
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
tuberculosis and treatment for 6 months 3 | 409
Colonic Neoplasms 2 | 142
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Diarrhea 2 | 253
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hepatomegaly 2 | 285
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mental Depression 2 | 333
Muscle Weakness 2 | 170
Myocardial Ischemia 2 | 169
Peripheral vascular disease 2 | 87
Poor growth 2 | 114
Prenatal onset 2 | 139
Progressive disorder 2 | 142
Prostatic Neoplasms 2 | 495
Recurrent respiratory infections 2 | 141
Very poor growth 2 | 114
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
chronic lymphosyte leukemia 2 | 204

Tissue

Endocrine System 54 | 18,159
Digestive Tract 53 | 17,369
Liver and Pancreas 53 | 16,750
Nervous System 53 | 16,725
Skin and soft tissues 53 | 17,230
Male tissues 52 | 17,142
Blood and immune system 51 | 16,909
Female tissues 51 | 17,400
Respiratory system 51 | 16,393
Urinary Tract 50 | 16,678
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 17 | 4,145
Kinase 2 | 634

PANTHER Protein Class (2)

kinase activator 55 | 55
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MOB kinase activator 3C MOB3C Tdark Enzyme 0.48 0.14 63
MOB-like protein phocein MOB4 Tbio Non-IDG -1.36459 24.7 114
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
G2/mitotic-specific cyclin-B3 CCNB3 Tbio Non-IDG -1.07824 12.1 272
Phosphorylase b kinase regulatory subunit alpha, liver isoform PHKA2 Tbio Kinase -2.21111 153.2 59
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform PHKA1 Tbio Kinase -1.17814 14.3 71
Phosphorylase b kinase regulatory subunit beta PHKB Tbio Enzyme -1.13261 11.6 113
Cyclin-O CCNO Tbio Non-IDG -1.55274 37.4 183
Double-stranded RNA-specific adenosine deaminase ADAR Tbio Enzyme -2.87338 784.2 197
Hsp90 co-chaperone Cdc37-like 1 CDC37L1 Tbio Non-IDG -1.08841 10.5 136