Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased bone mineral density 2 | 126
decreased lean body mass 2 | 135
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal eye pigmentation 1 | 3
absent pinna reflex 1 | 23
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased body weight 1 | 161
female infertility 1 | 60
increased circulating alkaline... 1 | 122
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
male infertility 1 | 123

Disease

ovarian cancer 10 | 8,520
osteosarcoma 8 | 7,950
Autosomal recessive predisposition 6 | 1,442
Carcinoma 6 | 11,493
Xeroderma pigmentosum 5 | 43
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Cockayne syndrome 4 | 60
Impaired cognition 4 | 96
Intellectual disability 4 | 1,016
Mental impairment 4 | 95
group 3 medulloblastoma 4 | 4,104
hypopigmented skin patch 4 | 59
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Arthralgia 3 | 90
Atrophic condition of skin 3 | 25
Basal cell carcinoma 3 | 54
Cataract 3 | 297
Conjunctival telangiectasis 3 | 14
Conjunctivitis 3 | 53
Conjunctivitis, recurrent 3 | 37
Cryptorchidism 3 | 296
Defective DNA repair after ultraviolet radiation damage 3 | 7
Dental abnormalities 3 | 60
Developmental regression 3 | 95
Dry skin 3 | 75
Dull intelligence 3 | 645
Ectropion 3 | 38
Electroencephalogram abnormal 3 | 101
Entropion 3 | 22
Erythema 3 | 58
Failure to gain weight 3 | 365
Fatigue 3 | 182
Fever 3 | 138
Flushing 3 | 60
Freckles 3 | 33
Hyperkeratosis 3 | 50
Hyperpigmented macules 3 | 42
Hypogonadism 3 | 173
Keratitis 3 | 62
Lens Opacities 3 | 231
Loss of developmental milestones 3 | 95
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Mental deterioration in childhood 3 | 95
Neurodevelopmental regression 3 | 95
Optic Atrophy 3 | 242
Papilloma 3 | 44
Pediatric failure to thrive 3 | 365
Photodysphoria 3 | 121
Photophobia 3 | 121
Photosensitivity of skin 3 | 51
Poikiloderma 3 | 14
Poor school performance 3 | 645
Progressive mental retardation 3 | 37
Prostate cancer 3 | 175
Prostatic Neoplasms 3 | 495
Psychomotor regression 3 | 95
Psychomotor regression beginning in infancy 3 | 95
Psychomotor regression in infants 3 | 95
Psychomotor regression, progressive 3 | 95
Sensorineural Hearing Loss (disorder) 3 | 284
Small head 3 | 374
Spider Veins 3 | 17
Strabismus 3 | 270
Telangiectasia of the skin 3 | 39
Telangiectasis 3 | 36
Thin skin 3 | 47
Tooth Abnormalities 3 | 69
Xerosis 3 | 75
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
non primary Sjogren syndrome sicca 3 | 891
tuberculosis and treatment for 6 months 3 | 409
Acquired scoliosis 2 | 281
Curvature of spine 2 | 282
Decreased platelet count 2 | 111
Decreased tendon reflex 2 | 122
Diarrhea 2 | 253
Disease Progression 2 | 136
Fanconi anemia 2 | 56
Glioma 2 | 74
Liver neoplasms 2 | 130
Lung Neoplasms 2 | 232
Mental deterioration 2 | 32
Microcephaly 2 | 166
Multiple myeloma 2 | 1,332
Short stature 2 | 531
Thrombocytopenia 2 | 197
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
ductal carcinoma in situ 2 | 1,745
medulloblastoma 2 | 720
primitive neuroectodermal tumor 2 | 3,035

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 1 | 4,145

PANTHER Protein Class (2)

damaged DNA-binding protein 11 | 11
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Microcephalin MCPH1 Tbio Non-IDG -1.96863 109.3 260
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
UV excision repair protein RAD23 homolog A RAD23A Tbio Non-IDG -1.57282 35.7 356
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.21142 154.0 208
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.87504 739.6 379
Nibrin NBN Tbio Non-IDG -1.95649 97.2 1094
DNA-3-methyladenine glycosylase MPG Tchem Enzyme -2.84708 687.5 316
Aprataxin APTX Tbio Non-IDG -2.02120 111.6 170
DNA damage-binding protein 2 DDB2 Tbio Non-IDG -2.07539 123.8 172