Development Level

Tbio 8 | 11,445
Tchem 8 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

IMPC Phenotype

abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
hemorrhage 1 | 23
premature death 1 | 5
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2

Disease

Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
ovarian cancer 7 | 8,520
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
Alzheimer's disease 5 | 658
Cancer 5 | 2,499
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer Disease 3 | 83
Amyloidosis 3 | 67
Amyotrophic lateral sclerosis type 3 3 | 17
Dementia 3 | 175
Down syndrome 3 | 499
Heart failure 3 | 162
Neurodegenerative disease 3 | 414
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
ALZHEIMER DISEASE 2 2 | 5
Alzheimer Disease 4 2 | 3
Amyotrophic lateral sclerosis 2 | 451
Amyotrophic lateral sclerosis type 1 2 | 23
Asphyxia neonatorum 2 | 11
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Cerebral atrophy 2 | 178
Cerebrovascular disease 2 | 238
Congestive heart failure 2 | 113
Depressive disorder 2 | 409
Dilated cardiomyopathy 2 | 56
Familial isolated dilated cardiomyopathy 2 | 41
Frontotemporal dementia 2 | 51
Kidney Diseases 2 | 114
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
Mental Depression 2 | 333
Neuronal loss 2 | 25
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Small head 2 | 374
Syncope 2 | 22
Toxic encephalopathy 2 | 141
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
interstitial lung disease 2 | 298
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
sarcoidosis 2 | 370
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Albuminuria 1 | 21
Apraxia 1 | 26
CD40 deficiency 1 | 4
Chronic Kidney Diseases 1 | 13
Compulsive hoarding 1 | 7
Dysphasia 1 | 23
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Hyperphagia 1 | 23
Hyperthyroidism 1 | 53
Increased appetite (finding) 1 | 23
Lateral sclerosis 1 | 15
Liddle syndrome 1 | 14
Memory Disorders 1 | 40
Neurodegenerative Diseases 1 | 38
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Progressive renal failure 1 | 13
Sensory peripheral neuropathy 1 | 10
Ureteral obstruction 1 | 33

Tissue

Endocrine System 21 | 18,159
Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Enzyme 17 | 4,145
Non-IDG 4 | 12,091

PANTHER Protein Class (2)

aspartic protease 21 | 21
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
RNA helicase 35 | 35
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Signal peptide peptidase-like 2C SPPL2C Tbio Enzyme -0.29003 1.44 33
Pepsin A-4 PGA4 Tbio Enzyme -1.47130 28.5 118
Pepsin A-3 PGA3 Tbio Enzyme -1.47858 28.8 123
Pepsin A-5 PGA5 Tclin Enzyme -1.97335 91.2 100
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Gastricsin PGC Tchem Enzyme -2.74445 526.6 286
Beta-secretase 1 BACE1 Tchem Enzyme -3.37358 2003.3 647
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Signal peptide peptidase-like 2A SPPL2A Tbio Enzyme -1.34035 24.0 84