Development Level

Tbio 18 | 11,445
Tdark 17 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal neural tube closure 1 | 46
abnormal retinal vasculature m... 1 | 27
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased heart left ventricle... 1 | 28
decreased monocyte cell number 1 | 8
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
increased bone mineral content 1 | 108
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased urine magnesium leve... 1 | 2
prenatal lethality prior to he... 1 | 87
thin ventricular wall 1 | 24

Disease

Carcinoma 25 | 11,493
Kidney cancer 13 | 2,613
osteosarcoma 12 | 7,950
group 3 medulloblastoma 10 | 4,104
ovarian cancer 10 | 8,520
medulloblastoma, large-cell 7 | 6,241
astrocytic glioma 6 | 2,597
glioblastoma 6 | 5,792
Acute leukemia 5 | 15
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
acute quadriplegic myopathy 4 | 1,158
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
malignant mesothelioma 3 | 3,232
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Neuronal ceroid lipofuscinosis 1 2 | 15
Rheumatoid arthritis 2 | 1,191
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
pancreatic cancer 2 | 2,398
posterior fossa group B ependymoma 2 | 416
Acute vascular insufficiency of intestine 1 | 4
Alzheimer's disease 1 | 658
Anemia 1 | 365
Astigmatism 1 | 54
Astrocytoma, Pilocytic 1 | 3,081
Autoimmune thyroiditis 1 | 27
Azoospermia 1 | 110
Bipolar Disorder 1 | 666
Bloom syndrome 1 | 29
CHARGE syndrome 1 | 26
Choanal Atresia 1 | 42
Coloboma 1 | 51
Corneal edema 1 | 14
Esophageal atresia with or without tracheoesophageal fistula 1 | 21
Fanconi anemia 1 | 56
Gaucher disease type 1 1 | 180
Globe disease 1 | 67
Heart disease 1 | 306
Hemolytic anemia 1 | 77
Hyperopia 1 | 70
Hypospadias 1 | 53
Influenza 1 | 142
Keratitis 1 | 62
Keratoconus 1 | 113
Kidney disease 1 | 430
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver cancer 1 | 604
Melanoma 1 | 711
Microphthalmia with limb anomalies 1 | 40
Moved to 227650 and 609644 1 | 1
Myopia 1 | 176
Norum disease 1 | 2
Ophthalmoplegia 1 | 106
Orofacial cleft 1 | 54
Protein C deficiency 1 | 19
Pseudopterygium 1 | 1
Retinitis Pigmentosa 1 | 226
Skin cancer 1 | 469
Syndactyly 1 | 88
Variegate Porphyria 1 | 10
Waldenstrons macroglobulinemia 1 | 765
Xeroderma pigmentosum group F 1 | 22
active ulcerative colitis 1 | 764
chronic rhinosinusitis 1 | 512
esophageal atresia/tracheoesophageal fistula 1 | 22
gastric cancer 1 | 459
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
pancreatic carcinoma 1 | 562
permanent atrial fibrillation 1 | 45
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 34 | 18,159
Nervous System 29 | 16,725
Respiratory system 28 | 16,393
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Skin and soft tissues 26 | 17,230
Blood and immune system 24 | 16,909
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Urinary Tract 24 | 16,678

Target Family

Enzyme 18 | 4,145
Non-IDG 16 | 12,091
Epigenetic 1 | 242

PANTHER Protein Class (2)

RNA helicase 35 | 35
protein kinase 257 | 257
serine protease 175 | 175
ribosomal protein 152 | 152
cysteine protease 142 | 142
metalloprotease 135 | 135
mRNA processing factor 122 | 122
calmodulin 113 | 113
chromatin/chromatin-binding pr... 106 | 106
serine protease inhibitor 94 | 94
non-motor actin binding protei... 90 | 90
homeodomain transcription fact... 88 | 88
small GTPase 81 | 81
guanyl-nucleotide exchange fac... 77 | 77
translation factor 76 | 76
ligand-gated ion channel 69 | 69
microtubule binding motor prot... 62 | 62
histone 61 | 61
non-motor microtubule binding ... 57 | 57
kinase activator 55 | 55
chemokine 48 | 48
DNA-directed RNA polymerase 46 | 46
ribonucleoprotein 44 | 44
heterotrimeric G-protein 43 | 43
protein phosphatase 41 | 41
nucleotide kinase 37 | 37
phosphatase inhibitor 34 | 34
nucleotide phosphatase 33 | 33
actin and actin related protei... 31 | 31
kinase inhibitor 31 | 31
phospholipase 30 | 30
ATP synthase 28 | 28
DNA helicase 28 | 28
actin binding motor protein 27 | 27
C2H2 zinc finger transcription... 25 | 25
calcium channel 23 | 23
DNA-directed DNA polymerase 22 | 22
endoribonuclease 22 | 22
tubulin 22 | 22
aspartic protease 21 | 21
exoribonuclease 21 | 21
type I cytokine receptor 20 | 20
anion channel 19 | 19
carbohydrate kinase 17 | 17
endodeoxyribonuclease 15 | 15
intermediate filament binding ... 15 | 15
neuropeptide 15 | 15
potassium channel 15 | 15
DNA methyltransferase 12 | 12
type II cytokine receptor 12 | 12
RNA methyltransferase 11 | 11
damaged DNA-binding protein 11 | 11
tumor necrosis factor family m... 11 | 11
sodium channel 9 | 9
neurotrophic factor 8 | 8
replication origin binding pro... 8 | 8
winged helix/forkhead transcri... 8 | 8
carbohydrate phosphatase 6 | 6
amino acid kinase 5 | 5
guanylate cyclase 5 | 5
DNA topoisomerase 4 | 4
interleukin superfamily 4 | 4
CREB-related transcription fac... 3 | 3
C4 zinc finger nuclear recepto... 2 | 2
DNA photolyase 2 | 2
Lambda repressor-like transcri... 2 | 2
cysteine protease inhibitor 2 | 2
tumor necrosis factor receptor 2 | 2
DNA glycosylase 1 | 1
DNA polymerase processivity fa... 1 | 1
centromere DNA-binding protein 1 | 1
exodeoxyribonuclease 1 | 1
phosphatase activator 1 | 1
primase 1 | 1
reverse transcriptase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
Putative ATP-dependent RNA helicase DHX30 DHX30 Tbio Enzyme -0.86783 7.74 109
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 DHX15 Tbio Enzyme -1.74929 55.5 106
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 DHX38 Tbio Enzyme -1.62527 42.6 88
ATP-dependent RNA helicase DHX8 DHX8 Tbio Enzyme -1.53695 33.3 137
Integrator complex subunit 6 INTS6 Tbio Non-IDG -2.07240 118.9 80
ATP-dependent RNA helicase DHX36 DHX36 Tbio Enzyme -1.55120 37.4 112
Probable ATP-dependent RNA helicase DHX40 DHX40 Tdark Enzyme -1.36067 20.6 23
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 DHX16 Tbio Enzyme -1.51980 31.4 78
Fanconi anemia group M protein FANCM Tbio Non-IDG -1.71483 59.3 115