Development Level

Tbio 9 | 11,445
Tchem 7 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal glucose homeostasis 1 | 4
abnormal tail movements 1 | 12
hyperactivity 1 | 148
increased bone mineral content 1 | 108
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 12 | 11,493
ovarian cancer 12 | 8,520
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
psoriasis 9 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
osteosarcoma 7 | 7,950
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Liver Cirrhosis, Experimental 5 | 769
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Autosomal recessive predisposition 3 | 1,442
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
Neuropathy 3 | 261
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Erythropoietic protoporphyria 2 | 15
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Huntington's disease 2 | 76
Major Depressive Disorder 2 | 301
Maple syrup urine disease 2 | 24
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Primary hyperoxaluria 2 | 15
Sideroblastic anemia 2 | 20
Unipolar Depression 2 | 250
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
chronic lymphosyte leukemia 2 | 204
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
Acquired immunodeficiency syndrome 1 | 197
Anemia, Sideroblastic 1 | 7
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Atrioventricular block 1 | 35
Autosomal recessive polycystic kidney disease 1 | 41
Bone pain 1 | 42
Calcinosis 1 | 70
Childhood onset 1 | 38
Death in childhood 1 | 14
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Depressed mood 1 | 17
Fatty Liver 1 | 70
Hematuria 1 | 36
Hepatitis 1 | 67
Hyperornithinemia 1 | 2
Increased calcium level in kidney 1 | 21
Infection of bone 1 | 19
Kidney Neoplasms 1 | 37
Lipid storage disease 1 | 8
Liver Neoplasms, Experimental 1 | 59
Metabolic acidosis 1 | 90
Microcytic hypochromic anemia (disorder) 1 | 10
Pallor 1 | 40
Pathological fracture 1 | 20
Peripheral Neuropathy 1 | 134
Precancerous Conditions 1 | 80
Psychomotor Disorders 1 | 7
Serine deficiency 1 | 9
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Spinocerebellar ataxia type 7 1 | 13
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Tall stature 1 | 34
X- linked recessive 1 | 110
X-linked sideroblastic anemia 1 | 4
inflammatory breast cancer 1 | 286
twin-to-twin transfusion syndrome 1 | 12
uncontrolled asthma 1 | 56

Tissue

Skin and soft tissues 18 | 17,230
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Urinary Tract 17 | 16,678
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Cardiovascular System 15 | 15,192
Nervous System 15 | 16,725

Target Family

Enzyme 18 | 4,145

PANTHER Protein Class (1)

transaminase 18 | 18
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

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