Development Level

Tbio 172 | 11,445
Tchem 46 | 1,598
Tdark 35 | 6,588
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 9 | 979
enlarged heart 6 | 210
short tibia 5 | 97
abnormal eye morphology 4 | 68
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
decreased vertical activity 4 | 208
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
abnormal lung morphology 2 | 26
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
abnormal tooth morphology 2 | 24
absent testes 2 | 6
decreased body weight 2 | 161
decreased circulating bilirubi... 2 | 19
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
increased bone mineral content 2 | 108
increased circulating glucose ... 2 | 24
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal duodenum morphology 1 | 4
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye size 1 | 7
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal humerus morphology 1 | 11
abnormal iris morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent vibrissae 1 | 12
cataract 1 | 92
decreased body temperature 1 | 2
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged testis 1 | 6
head bobbing 1 | 5
hydrometra 1 | 53
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating insulin ... 1 | 3
increased circulating sodium l... 1 | 71
increased heart left ventricle... 1 | 4
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
kinked tail 1 | 2
mammalian phenotype 1 | 17
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Carcinoma 178 | 11,493
ovarian cancer 124 | 8,520
psoriasis 124 | 6,694
glioblastoma 101 | 5,792
lung cancer 98 | 4,740
medulloblastoma, large-cell 90 | 6,241
osteosarcoma 90 | 7,950
lung carcinoma 84 | 2,843
ependymoma 80 | 4,679
Cancer 79 | 2,499
Breast cancer 78 | 3,578
non-small cell lung cancer 72 | 2,890
atypical teratoid / rhabdoid tumor 71 | 5,112
pancreatic cancer 70 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 69 | 2,955
malignant mesothelioma 64 | 3,232
cystic fibrosis 63 | 1,696
adult high grade glioma 62 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 61 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 61 | 3,291
interstitial cystitis 60 | 2,312
Astrocytoma, Pilocytic 59 | 3,081
Kidney cancer 59 | 2,613
lung adenocarcinoma 59 | 2,716
invasive ductal carcinoma 53 | 2,951
ulcerative colitis 51 | 1,819
group 3 medulloblastoma 50 | 4,104
subependymal giant cell astrocytoma 50 | 2,287
primitive neuroectodermal tumor 45 | 3,035
primary pancreatic ductal adenocarcinoma 42 | 1,109
Autosomal recessive predisposition 41 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,962
gastric carcinoma 39 | 807
pituitary cancer 38 | 1,972
oligodendroglioma 37 | 2,850
colon cancer 36 | 1,478
cutaneous lupus erythematosus 36 | 1,057
adrenocortical carcinoma 35 | 1,428
breast carcinoma 34 | 1,638
ductal carcinoma in situ 34 | 1,745
juvenile dermatomyositis 34 | 1,187
astrocytic glioma 33 | 2,597
tuberculosis 33 | 2,010
Liver Cirrhosis, Experimental 32 | 769
diabetes mellitus 32 | 1,728
Atopic dermatitis 31 | 952
Duchenne muscular dystrophy 27 | 601
esophageal adenocarcinoma 27 | 737
active Crohn's disease 26 | 922
active ulcerative colitis 26 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 510
Melanoma 23 | 711
Schizophrenia 23 | 1,160
acute quadriplegic myopathy 23 | 1,158
primary Sjogren syndrome 22 | 735
Kidney disease 21 | 430
Rheumatoid arthritis 21 | 1,191
Skin cancer 21 | 469
Vascular disease 21 | 319
nasopharyngeal carcinoma 21 | 1,058
pediatric high grade glioma 20 | 1,064
Obesity 19 | 678
astrocytoma 19 | 1,146
Alzheimer's disease 18 | 658
Bipolar Disorder 18 | 666
Breast Neoplasms 17 | 445
Mammary Neoplasms 17 | 425
dermatomyositis 17 | 966
fibroadenoma 17 | 559
Arthritis 16 | 290
Liver cancer 16 | 604
Stomach Neoplasms 16 | 300
group 4 medulloblastoma 16 | 1,855
sonic hedgehog group medulloblastoma 16 | 467
Endometriosis 15 | 540
medulloblastoma 15 | 720
spina bifida 15 | 1,074
Colorectal Neoplasms 14 | 243
Heart disease 14 | 306
Liver disease 14 | 237
Pick disease 14 | 1,894
Prostatic Neoplasms 14 | 495
nephrosclerosis 14 | 333
Down syndrome 13 | 499
Multiple myeloma 13 | 1,332
Anemia 12 | 365
Cerebrovascular disease 12 | 238
Liver Cirrhosis 12 | 181
non-small cell lung carcinoma 12 | 317
Asthma 11 | 385
Atherosclerosis 11 | 291
Carcinoma, Hepatocellular 11 | 228
Chronic obstructive pulmonary disease 11 | 184
Hypertension 11 | 396
Intellectual disability 11 | 1,016
Liver carcinoma 11 | 240
Multiple Sclerosis 11 | 540
aldosterone-producing adenoma 11 | 665
limb girdle muscular dystrophy 2A 11 | 213
non diabetic and post-ischemic heart failure 11 | 200

Tissue

Endocrine System 240 | 18,159
Digestive Tract 232 | 17,369
Female tissues 232 | 17,400
Male tissues 228 | 17,142
Skin and soft tissues 227 | 17,230
Liver and Pancreas 221 | 16,750
Urinary Tract 221 | 16,678
Blood and immune system 219 | 16,909
Nervous System 210 | 16,725
Respiratory system 209 | 16,393
Cardiovascular System 191 | 15,192

Target Family

Non-IDG 176 | 12,091
Enzyme 57 | 4,145
Transporter 12 | 473
GPCR 11 | 408

PANTHER Protein Class (1)

protease inhibitor 256 | 256
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Butyrophilin-like protein 10 BTNL10 Tdark Non-IDG 0.00000 0
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
IgGFc-binding protein FCGBP Tbio Non-IDG -1.31482 19.9 0
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Beclin-2 BECN2 Tbio Non-IDG 0.00000 87
WAP four-disulfide core domain protein 12 WFDC12 Tbio Non-IDG -0.92987 8.23 54
Butyrophilin subfamily 2 member A2 BTN2A2 Tdark Non-IDG -0.21927 2.32 84
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Serpin A9 SERPINA9 Tbio Non-IDG -1.94929 88.4 132