Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased basophil cell number 1 | 16
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
preweaning lethality, complete... 1 | 979

Disease

Intellectual disability 3 | 1,016
Muscle hypotonia 3 | 571
Vomiting 3 | 116
atypical teratoid / rhabdoid tumor 3 | 5,112
medulloblastoma, large-cell 3 | 6,241
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Cardiomyopathies 2 | 110
Cognitive delay 2 | 608
Congenital disorder of glycosylation 2 | 54
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Lesch-Nyhan syndrome 2 | 12
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Abnormal amniotic fluid 1 | 6
Anemia, Megaloblastic 1 | 16
Anorexia 1 | 43
Antithrombin III deficiency 1 | 14
Atrophy of testis 1 | 14
Barrett's esophagus 1 | 182
Biotinidase deficiency 1 | 14
Carcinoma, Squamous Cell 1 | 110
Chronic kidney disease stage 5 1 | 31
Colorectal Neoplasms 1 | 243
Comatose 1 | 56
Cystic kidney 1 | 30
Decreased platelet count 1 | 111
Deglutition Disorders 1 | 132
Dehydration 1 | 40
DiGeorge syndrome 1 | 47
Esotropia 1 | 31
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Factor XI Deficiency 1 | 12
Fibrosis, Liver 1 | 32
Galactosemia 1 | 19
Generalized osteopenia 1 | 99
Gout 1 | 106
Hematuria 1 | 36
Hemiplegia and hemiparesis 1 | 38
Homocystinuria 1 | 21
Hyperammonemia 1 | 30
Hyperkyphosis 1 | 111
Hyperuricemia 1 | 49
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Immunologic Deficiency Syndromes 1 | 113
Increased number of platelets 1 | 14
Isoelectric focusing of serum transferrin consistent with CDG type I 1 | 10
Kyphosis deformity of spine 1 | 114
Lethargy 1 | 77
Metabolic acidosis 1 | 90
Methylmalonic aciduria 1 | 9
Mild Mental Retardation 1 | 70
Moderate mental retardation (I.Q. 35-49) 1 | 28
Muscle Weakness 1 | 170
N syndrome 1 | 6
Nausea and vomiting 1 | 97
Nephritis, Tubulointerstitial 1 | 8
Nephrotic Syndrome 1 | 78
Osteopenia 1 | 99
Ovarian Failure, Premature 1 | 9
Ovarian Neoplasms 1 | 102
Pancreatitis 1 | 123
Peripheral Neuropathy 1 | 134
Polyneuropathy 1 | 64
Primary hypogonadism 1 | 37
Renal cyst 1 | 30
Respiratory distress 1 | 43
Squamous cell carcinoma 1 | 129
Steatohepatitis 1 | 44
Thin upper lip vermilion 1 | 67
Thrombocytopenia 1 | 197
Thrombocytosis 1 | 38
Vitamin B12 deficiency 1 | 20
X- linked recessive 1 | 110
Xeroderma pigmentosum 1 | 43
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

PANTHER Protein Class (1)

mutase 5 | 5
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Phosphomannomutase 2 PMM2 Tchem Enzyme -2.12990 128.2 153
Phosphoribosyltransferase domain-containing protein 1 PRTFDC1 Tbio Enzyme -0.80000 6.26 172
Hypoxanthine-guanine phosphoribosyltransferase HPRT1 Tchem Enzyme -3.37307 2350.7 381
Phosphomannomutase 1 PMM1 Tbio Enzyme -1.61681 38.9 50