Development Level

Tbio 13 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
small kidney 1 | 16

Disease

Carcinoma 14 | 11,493
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
ovarian cancer 10 | 8,520
interstitial cystitis 9 | 2,312
Liver cancer 7 | 604
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
non-small cell lung cancer 7 | 2,890
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
Bullous pemphigoid 6 | 18
ependymoma 6 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
astrocytic glioma 5 | 2,597
esophageal adenocarcinoma 5 | 737
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
medulloblastoma, large-cell 5 | 6,241
Melanoma 4 | 711
Pemphigus 4 | 23
Pick disease 4 | 1,894
acute myeloid leukemia 4 | 783
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Arrhythmogenic right ventricular cardiomyopathy 3 | 30
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Epidermolysis bullosa 3 | 21
Failure to gain weight 3 | 365
Fragile skin 3 | 18
Palmoplantar keratosis 3 | 74
Pediatric failure to thrive 3 | 365
Short stature 3 | 531
Skin cancer 3 | 469
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ANONYCHIA 2 | 20
Alopecia 2 | 115
Atrophic scar 2 | 18
Broad flat nasal bridge 2 | 236
Cancer 2 | 2,499
Cardiomyopathy 2 | 116
Cardiomyopathy, right ventricular 2 | 7
Chronic Lymphocytic Leukemia 2 | 262
Congenital Epicanthus 2 | 177
Contracture 2 | 96
Contracture of joint 2 | 93
DOID:2627 2 | 94
Dental caries 2 | 164
Dilated cardiomyopathy 2 | 56
Dystrophia unguium 2 | 53
Endometrial cancer 2 | 311
Enophthalmos 2 | 75
Epidermolysis bullosa simplex with muscular dystrophy 2 | 3
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Immunologic Deficiency Syndromes 2 | 113
Large intestine cancer 2 | 126
Muscle hypotonia 2 | 571
Nail Diseases 2 | 24
Nail abnormality 2 | 22
Nail dysplasia 2 | 52
Nasal bridge wide 2 | 236
Oral mucosal blistering 2 | 10
Rotting teeth 2 | 73
Schizophrenia 2 | 1,160
Short neck 2 | 140
Skin Erosion 2 | 12
Sudden Cardiac Death 2 | 29
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
hereditary spastic paraplegia 2 | 318
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
Branchiootic syndrome 1 | 12
Cellular schwannoma 1 | 2
Dysphasia 1 | 23
High pitched voice 1 | 23
LEOPARD syndrome 1 | 20
Pemphigus vulgaris 1 | 5
Pulmonary Fibrosis, Idiopathic 1 | 12

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Nervous System 13 | 16,725

Target Family

Non-IDG 15 | 12,091

PANTHER Protein Class (1)

intermediate filament 15 | 15
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
cysteine protease 69 | 69
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Envoplakin-like protein EVPLL Tdark Non-IDG 0.00000 61
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Plakophilin-1 PKP1 Tbio Non-IDG -1.86062 76.3 103
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Catenin delta-2 CTNND2 Tbio Non-IDG -1.91434 95.4 137
Armadillo repeat protein deleted in velo-cardio-facial syndrome ARVCF Tbio Non-IDG -1.37786 24.5 71
Epiplakin EPPK1 Tdark Non-IDG -1.29990 21.1 0
Dystonin DST Tbio Non-IDG -2.73231 506.0 127