Development Level

Tbio 42 | 11,445
Tdark 22 | 6,588
Tchem 3 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
embryonic lethality prior to t... 2 | 278
increased circulating alanine ... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating aspartat... 2 | 15
increased mean corpuscular vol... 2 | 92
increased red blood cell distr... 2 | 34
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal QT variability 1 | 10
abnormal bone mineralization 1 | 38
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal heart position or ori... 1 | 1
abnormal lung morphology 1 | 26
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
hypoactivity 1 | 132
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
prolonged PR interval 1 | 15
small seminal vesicle 1 | 10

Disease

Carcinoma 47 | 11,493
osteosarcoma 34 | 7,950
ovarian cancer 32 | 8,520
lung cancer 21 | 4,740
psoriasis 21 | 6,694
medulloblastoma, large-cell 20 | 6,241
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
malignant mesothelioma 16 | 3,232
Kidney cancer 14 | 2,613
Breast cancer 13 | 3,578
ependymoma 12 | 4,679
invasive ductal carcinoma 12 | 2,951
lung carcinoma 11 | 2,843
non-small cell lung cancer 11 | 2,890
adult high grade glioma 10 | 3,801
Cancer 9 | 2,499
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
oligodendroglioma 9 | 2,850
tuberculosis 9 | 2,010
diabetes mellitus 8 | 1,728
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
subependymal giant cell astrocytoma 7 | 2,287
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
Autosomal recessive predisposition 5 | 1,442
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
Liver Cirrhosis, Experimental 4 | 769
Obesity 4 | 678
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
sonic hedgehog group medulloblastoma 4 | 467
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Hyperglycemia 3 | 137
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Parkinson's disease 3 | 392
Seizures 3 | 596
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
tuberculosis and treatment for 3 months 3 | 179
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Blepharoptosis 2 | 231
Cerebellar Ataxia 2 | 304
Deglutition Disorders 2 | 132
Exocrine pancreatic insufficiency 2 | 32
Failure to gain weight 2 | 365
Feeding difficulties 2 | 127
Glaucoma 2 | 239
Hyperammonemia 2 | 30
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Machado-Joseph disease 2 | 18
Muscle Cramp 2 | 55
Pancreatic steatorrhea 2 | 6
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Progressive disorder 2 | 142
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Rheumatoid arthritis 2 | 1,191
Steatorrhea 2 | 34
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
Warburg micro syndrome 2 | 18
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
gastric cancer 2 | 459
gastric carcinoma 2 | 807
pancreatic carcinoma 2 | 562
primary Sjogren syndrome 2 | 735
Blindness, Cortical 1 | 24
Cortical visual impairment 1 | 24
Ornithine translocase deficiency 1 | 7
Protein avoidance 1 | 5

Tissue

Endocrine System 69 | 18,159
Blood and immune system 65 | 16,909
Digestive Tract 62 | 17,369
Female tissues 62 | 17,400
Male tissues 62 | 17,142
Skin and soft tissues 62 | 17,230
Urinary Tract 62 | 16,678
Liver and Pancreas 61 | 16,750
Respiratory system 61 | 16,393
Nervous System 58 | 16,725
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 20 | 4,145
Kinase 1 | 634

PANTHER Protein Class (1)

cysteine protease 69 | 69
protease 516 | 516
RNA binding protein 483 | 483
kinase 362 | 362
DNA binding protein 342 | 342
protease inhibitor 256 | 256
G-protein coupled receptor 221 | 221
actin family cytoskeletal prot... 221 | 221
KRAB box transcription factor 193 | 193
microtubule family cytoskeleta... 189 | 189
ion channel 186 | 186
G-protein modulator 179 | 179
dehydrogenase 173 | 173
phosphatase 163 | 163
G-protein 131 | 131
cation transporter 127 | 127
glycosyltransferase 121 | 121
nuclease 110 | 110
growth factor 104 | 104
cytokine 101 | 101
kinase modulator 99 | 99
ubiquitin-protein ligase 99 | 99
helix-turn-helix transcription... 98 | 98
transcription cofactor 96 | 96
serine protease 79 | 79
immunoglobulin 76 | 76
helicase 75 | 75
membrane trafficking regulator... 75 | 75
zinc finger transcription fact... 74 | 74
immunoglobulin receptor superf... 71 | 71
winged helix/forkhead transcri... 70 | 70
acetyltransferase 68 | 68
oxygenase 68 | 68
basic helix-loop-helix transcr... 60 | 60
acyltransferase 59 | 59
extracellular matrix glycoprot... 53 | 53
methyltransferase 53 | 53
peptide hormone 52 | 52
phosphatase modulator 51 | 51
intracellular calcium-sensing ... 47 | 47
membrane-bound signaling molec... 47 | 47
reductase 42 | 42
C4 zinc finger nuclear recepto... 41 | 41
vesicle coat protein 40 | 40
oxidase 39 | 39
ATP-binding cassette (ABC) tra... 36 | 36
cytokine receptor 36 | 36
tight junction 35 | 35
esterase 32 | 32
extracellular matrix structura... 31 | 31
SNARE protein 30 | 30
lipase 30 | 30
amino acid transporter 28 | 28
basic leucine zipper transcrip... 27 | 27
Rel homology transcription fac... 25 | 25
aminoacyl-tRNA synthetase 24 | 24
peroxidase 24 | 24
dehydratase 23 | 23
deaminase 22 | 22
gap junction 21 | 21
major histocompatibility compl... 21 | 21
carbohydrate transporter 20 | 20
nucleotidyltransferase 20 | 20
transaminase 18 | 18
glycosidase 16 | 16
metalloprotease 16 | 16
homeodomain transcription fact... 15 | 15
intermediate filament 15 | 15
mitochondrial carrier protein 15 | 15
HMG box transcription factor 14 | 14
apolipoprotein 13 | 13
chaperonin 13 | 13
annexin 12 | 12
decarboxylase 12 | 12
Hsp90 family chaperone 9 | 9
phosphorylase 9 | 9
glucosidase 8 | 8
cadherin 7 | 7
cyclase 7 | 7
antibacterial response protein 6 | 6
deacetylase 6 | 6
phosphodiesterase 6 | 6
MADS box transcription factor 5 | 5
galactosidase 5 | 5
hydroxylase 5 | 5
mutase 5 | 5
immunoglobulin superfamily cel... 4 | 4
pyrophosphatase 4 | 4
P53-like transcription factor 3 | 3
Runt transcription factor 3 | 3
TATA-binding transcription fac... 3 | 3
myelin protein 3 | 3
amylase 2 | 2
epimerase/racemase 2 | 2
protein kinase receptor 2 | 2
aldolase 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
TBC1 domain family member 13 TBC1D13 Tdark Non-IDG -0.10266 1.34 92
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.72004 3.69 184
TBC1 domain family member 26 TBC1D26 Tdark Non-IDG 0.00000 1.00 47
TBC1 domain family member 3G TBC1D3G Tdark Non-IDG 0.00000 5
TBC1 domain family member 8 TBC1D8 Tdark Non-IDG 0.21 0.48 69
40S ribosomal protein S3a RPS3A Tbio Non-IDG -2.19842 141.5 139
TBC1 domain family member 9B TBC1D9B Tdark Non-IDG 0.66 0.43 29
Phosphoribosylformylglycinamidine synthase PFAS Tbio Enzyme -2.83741 653.1 88
TBC1 domain family member 2A TBC1D2 Tbio Non-IDG -1.28188 18.5 80