Development Level

Tbio 167 | 11,445
Tdark 50 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 14 | 979
decreased total body fat amoun... 6 | 207
abnormal behavior 5 | 298
decreased circulating insulin ... 4 | 76
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
increased lean body mass 4 | 172
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
hyperactivity 3 | 148
increased bone mineral density 3 | 72
increased total body fat amoun... 3 | 134
abnormal sleep behavior 2 | 70
abnormal testis morphology 2 | 43
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased circulating lactate ... 2 | 3
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased heart rate 2 | 23
increased or absent threshold ... 2 | 101
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal nail morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin appearance 1 | 3
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
alopecia 1 | 1
cataract 1 | 92
decreased IgE level 1 | 6
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
limb grasping 1 | 41
mammalian phenotype 1 | 17
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 126 | 11,493
ovarian cancer 116 | 8,520
osteosarcoma 100 | 7,950
medulloblastoma, large-cell 84 | 6,241
glioblastoma 82 | 5,792
psoriasis 78 | 6,694
atypical teratoid / rhabdoid tumor 70 | 5,112
ependymoma 65 | 4,679
group 3 medulloblastoma 49 | 4,104
adult high grade glioma 47 | 3,801
Astrocytoma, Pilocytic 43 | 3,081
oligodendroglioma 43 | 2,850
astrocytic glioma 42 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,955
Breast cancer 41 | 3,578
lung cancer 41 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
lung carcinoma 39 | 2,843
Pick disease 35 | 1,894
malignant mesothelioma 34 | 3,232
primitive neuroectodermal tumor 34 | 3,035
invasive ductal carcinoma 33 | 2,951
subependymal giant cell astrocytoma 32 | 2,287
Kidney cancer 31 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
lung adenocarcinoma 28 | 2,716
Multiple myeloma 26 | 1,332
interstitial cystitis 26 | 2,312
pancreatic cancer 26 | 2,398
non-small cell lung cancer 25 | 2,890
group 4 medulloblastoma 23 | 1,855
pituitary cancer 23 | 1,972
dermatomyositis 21 | 966
acute quadriplegic myopathy 20 | 1,158
astrocytoma 20 | 1,146
breast carcinoma 20 | 1,638
spina bifida 19 | 1,074
tuberculosis 19 | 2,010
diabetes mellitus 18 | 1,728
Autosomal recessive predisposition 17 | 1,442
Rheumatoid arthritis 16 | 1,191
Waldenstrons macroglobulinemia 16 | 765
Intellectual disability 14 | 1,016
Schizophrenia 14 | 1,160
cystic fibrosis 14 | 1,696
ductal carcinoma in situ 14 | 1,745
Neurodegenerative disease 13 | 414
colon cancer 13 | 1,478
pediatric high grade glioma 13 | 1,064
Alzheimer's disease 12 | 658
juvenile dermatomyositis 12 | 1,187
non primary Sjogren syndrome sicca 11 | 891
ulcerative colitis 11 | 1,819
Amyotrophic lateral sclerosis 10 | 451
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Bipolar Disorder 9 | 666
Cancer 9 | 2,499
acute myeloid leukemia 9 | 783
esophageal adenocarcinoma 9 | 737
nasopharyngeal carcinoma 9 | 1,058
primary pancreatic ductal adenocarcinoma 9 | 1,109
progressive supranuclear palsy 9 | 676
Down syndrome 8 | 499
Epilepsy 8 | 792
Gaucher disease type 1 8 | 180
Hypomyelinating leukodystrophy 6 8 | 26
Tetanus 8 | 68
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
hereditary spastic paraplegia 8 | 318
medulloblastoma 8 | 720
Atopic dermatitis 7 | 952
Dull intelligence 7 | 645
Liver Cirrhosis, Experimental 7 | 769
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Muscle hypotonia 7 | 571
Poor school performance 7 | 645
Short stature 7 | 531
adrenocortical carcinoma 7 | 1,428
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic carcinoma 7 | 562
primary Sjogren syndrome 7 | 735
Cataract 8 multiple types 6 | 33
Duchenne muscular dystrophy 6 | 601
Dysarthria 6 | 192
Liver cancer 6 | 604
Melanoma 6 | 711
aldosterone-producing adenoma 6 | 665
gastric cancer 6 | 459
sarcoidosis 6 | 370
Type 2 diabetes mellitus 5 | 272
gastric carcinoma 5 | 807
hepatocellular carcinoma 5 | 547

Tissue

Endocrine System 210 | 18,159
Skin and soft tissues 206 | 17,230
Female tissues 205 | 17,400
Male tissues 205 | 17,142
Digestive Tract 203 | 17,369
Liver and Pancreas 203 | 16,750
Nervous System 202 | 16,725
Urinary Tract 199 | 16,678
Respiratory system 197 | 16,393
Blood and immune system 193 | 16,909
Cardiovascular System 187 | 15,192

Target Family

Non-IDG 213 | 12,091
Enzyme 3 | 4,145
Ion Channel 1 | 344

PANTHER Protein Class (0)

membrane traffic protein 217 | 217
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Golgin subfamily A member 6C GOLGA6C Tdark Non-IDG 0.00000 0
Golgin subfamily A member 6B GOLGA6B Tdark Non-IDG 0.00000 75
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
Putative synaptogyrin-2 like protein N/A Tdark Non-IDG -0.69433 7.83 0
Exocyst complex component 3-like protein EXOC3L1 Tdark Non-IDG 0.10 1.30 62
Protein Hook homolog 1 HOOK1 Tbio Non-IDG -1.16190 13.1 187
MARVEL domain-containing protein 1 MARVELD1 Tbio Non-IDG -1.58692 39.1 60
Otoferlin OTOF Tbio Non-IDG -2.05743 118.7 45