Development Level

Tbio 145 | 11,445
Tdark 29 | 6,588
Tchem 10 | 1,598
Tclin 7 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal coat-hair pigmentatio... 4 | 64
decreased total body fat amoun... 4 | 207
abnormal gait 3 | 69
abnormal sleep behavior 3 | 70
decreased body weight 3 | 161
abnormal behavioral response t... 2 | 66
abnormal lung morphology 2 | 26
abnormal snout morphology 2 | 23
abnormal tooth morphology 2 | 24
cataract 2 | 92
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
tremors 2 | 39
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal incisor morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal radius morphology 1 | 8
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
enlarged epididymis 1 | 31
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
mammalian phenotype 1 | 17
mydriasis 1 | 6
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
thick ventricular wall 1 | 7
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 130 | 11,493
psoriasis 88 | 6,694
osteosarcoma 83 | 7,950
ovarian cancer 73 | 8,520
glioblastoma 69 | 5,792
medulloblastoma, large-cell 62 | 6,241
lung cancer 59 | 4,740
interstitial cystitis 53 | 2,312
Breast cancer 52 | 3,578
lung carcinoma 52 | 2,843
atypical teratoid / rhabdoid tumor 51 | 5,112
invasive ductal carcinoma 48 | 2,951
ependymoma 47 | 4,679
adult high grade glioma 46 | 3,801
non-small cell lung cancer 46 | 2,890
Astrocytoma, Pilocytic 45 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
pancreatic cancer 44 | 2,398
Cancer 42 | 2,499
lung adenocarcinoma 42 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
malignant mesothelioma 39 | 3,232
tuberculosis 38 | 2,010
ulcerative colitis 38 | 1,819
Kidney cancer 31 | 2,613
group 3 medulloblastoma 29 | 4,104
subependymal giant cell astrocytoma 29 | 2,287
ductal carcinoma in situ 28 | 1,745
primary pancreatic ductal adenocarcinoma 25 | 1,109
primitive neuroectodermal tumor 25 | 3,035
Melanoma 24 | 711
cutaneous lupus erythematosus 24 | 1,057
oligodendroglioma 24 | 2,850
pituitary cancer 23 | 1,972
breast carcinoma 22 | 1,638
Atopic dermatitis 21 | 952
Liver Cirrhosis, Experimental 21 | 769
astrocytic glioma 21 | 2,597
colon cancer 20 | 1,478
mucosa-associated lymphoid tissue lymphoma 20 | 484
primary Sjogren syndrome 20 | 735
Rheumatoid arthritis 19 | 1,191
cystic fibrosis 18 | 1,696
Duchenne muscular dystrophy 17 | 601
esophageal adenocarcinoma 17 | 737
nasopharyngeal carcinoma 17 | 1,058
Schizophrenia 16 | 1,160
diabetes mellitus 16 | 1,728
group 4 medulloblastoma 16 | 1,855
Autosomal recessive predisposition 15 | 1,442
pediatric high grade glioma 15 | 1,064
gastric carcinoma 14 | 807
Skin cancer 13 | 469
dermatomyositis 13 | 966
non primary Sjogren syndrome sicca 13 | 891
pancreatic carcinoma 13 | 562
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
periodontitis 12 | 293
Down syndrome 11 | 499
Lymphoproliferative syndrome 11 | 58
Pick disease 11 | 1,894
Thrombocytopenia 11 | 197
astrocytoma 11 | 1,146
fibroadenoma 11 | 559
medulloblastoma 11 | 720
adrenocortical carcinoma 10 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
Multiple Sclerosis 9 | 540
acute myeloid leukemia 9 | 783
juvenile dermatomyositis 9 | 1,187
limb girdle muscular dystrophy 2A 9 | 213
spina bifida 9 | 1,074
Hypersensitivity reaction type II disease 8 | 253
acute quadriplegic myopathy 8 | 1,158
urothelial carcinoma 8 | 318
Anemia 7 | 365
Asthma 7 | 385
Becker muscular dystrophy 7 | 191
Chronic Lymphocytic Leukemia 7 | 262
Coronary artery disease 7 | 268
Endometriosis 7 | 540
Multiple myeloma 7 | 1,332
Short stature 7 | 531
facioscapulohumeral dystrophy 7 | 288
gastric cancer 7 | 459
posterior fossa group A ependymoma 7 | 468
sarcoidosis 7 | 370
Abortion, Spontaneous 6 | 109
Acquired metabolic disease 6 | 336
Atherosclerosis 6 | 291
Dermatitis 6 | 157
Motor delay 6 | 147
Muscle hypotonia 6 | 571
No development of motor milestones 6 | 147
Spontaneous abortion 6 | 113
active Crohn's disease 6 | 922
cystic fibrosis and chronic rhinosinusitis 6 | 214
head and neck cancer 6 | 271
sonic hedgehog group medulloblastoma 6 | 467

Tissue

Endocrine System 184 | 18,159
Female tissues 173 | 17,400
Skin and soft tissues 170 | 17,230
Digestive Tract 167 | 17,369
Blood and immune system 166 | 16,909
Male tissues 166 | 17,142
Respiratory system 160 | 16,393
Urinary Tract 158 | 16,678
Nervous System 156 | 16,725
Liver and Pancreas 155 | 16,750
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 185 | 12,091
GPCR 3 | 408
Ion Channel 2 | 344
Enzyme 1 | 4,145

PANTHER Protein Class (0)

cell adhesion molecule 191 | 191
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
calcium-binding protein 105 | 105
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Integrin beta-like protein 1 ITGBL1 Tbio Non-IDG -0.73415 6.42 83
Grifin GRIFIN Tdark Non-IDG 0.00000 0
Transmembrane protein 8B TMEM8B Tbio Non-IDG -1.34736 25.6 106
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Sialic acid-binding Ig-like lectin 11 SIGLEC11 Tbio Non-IDG 0.00000 173
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86