Development Level

Tbio 78 | 11,445
Tdark 21 | 6,588
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
enlarged spleen 2 | 41
abnormal brain morphology 1 | 13
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal placement of pupils 1 | 6
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged testis 1 | 6
hydroencephaly 1 | 14
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
long tibia 1 | 25
mammalian phenotype 1 | 17
mydriasis 1 | 6
narrow eye opening 1 | 12
small seminal vesicle 1 | 10
small thymus 1 | 16
syndactyly 1 | 23

Disease

Carcinoma 58 | 11,493
ovarian cancer 54 | 8,520
osteosarcoma 44 | 7,950
psoriasis 43 | 6,694
medulloblastoma, large-cell 38 | 6,241
glioblastoma 37 | 5,792
Breast cancer 29 | 3,578
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 28 | 4,679
Astrocytoma, Pilocytic 27 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
group 3 medulloblastoma 24 | 4,104
lung cancer 24 | 4,740
non-small cell lung cancer 24 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
adult high grade glioma 21 | 3,801
lung adenocarcinoma 21 | 2,716
lung carcinoma 20 | 2,843
oligodendroglioma 20 | 2,850
invasive ductal carcinoma 19 | 2,951
primitive neuroectodermal tumor 19 | 3,035
subependymal giant cell astrocytoma 19 | 2,287
malignant mesothelioma 18 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
astrocytic glioma 17 | 2,597
breast carcinoma 16 | 1,638
pancreatic cancer 15 | 2,398
cystic fibrosis 14 | 1,696
Kidney cancer 13 | 2,613
diabetes mellitus 13 | 1,728
interstitial cystitis 13 | 2,312
pituitary cancer 13 | 1,972
Cancer 12 | 2,499
acute quadriplegic myopathy 11 | 1,158
Multiple myeloma 10 | 1,332
Pick disease 10 | 1,894
Waldenstrons macroglobulinemia 10 | 765
spina bifida 10 | 1,074
ulcerative colitis 10 | 1,819
colon cancer 9 | 1,478
group 4 medulloblastoma 9 | 1,855
tuberculosis 9 | 2,010
adrenocortical carcinoma 8 | 1,428
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,187
primary pancreatic ductal adenocarcinoma 8 | 1,109
Duchenne muscular dystrophy 7 | 601
Hypertrophic Cardiomyopathy 7 | 117
Liver Cirrhosis, Experimental 7 | 769
Schizophrenia 7 | 1,160
active Crohn's disease 7 | 922
astrocytoma 7 | 1,146
pediatric high grade glioma 7 | 1,064
Amyotrophic lateral sclerosis 6 | 451
Atopic dermatitis 6 | 952
dermatomyositis 6 | 966
nasopharyngeal carcinoma 6 | 1,058
Cardiomyopathy 5 | 116
Down syndrome 5 | 499
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
hereditary spastic paraplegia 5 | 318
mucosa-associated lymphoid tissue lymphoma 5 | 484
non primary Sjogren syndrome sicca 5 | 891
sonic hedgehog group medulloblastoma 5 | 467
Autosomal recessive predisposition 4 | 1,442
Endometriosis 4 | 540
Epilepsy 4 | 792
Melanoma 4 | 711
Polycystic ovary syndrome 4 | 360
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
cutaneous lupus erythematosus 4 | 1,057
fibroadenoma 4 | 559
Alzheimer's disease 3 | 658
Becker muscular dystrophy 3 | 191
Bipolar Disorder 3 | 666
Cardiomyopathy, Hypertrophic 3 | 24
Dilated cardiomyopathy 3 | 56
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Muscular dystrophy 3 | 75
Myopathy 3 | 185
Neurodegenerative disease 3 | 414
Type 2 diabetes mellitus 3 | 272
Wolf-Hirschhorn syndrome 3 | 32
active ulcerative colitis 3 | 764
atypical teratoid/rhabdoid tumor 3 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric cancer 3 | 459
hepatocellular carcinoma 3 | 547
interstitial lung disease 3 | 298
medulloblastoma 3 | 720
posterior fossa group B ependymoma 3 | 416
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
Myocardial Ischemia 2 | 169
Vascular disease 2 | 319
chronic rhinosinusitis 2 | 512

Tissue

Endocrine System 102 | 18,159
Digestive Tract 101 | 17,369
Male tissues 101 | 17,142
Female tissues 99 | 17,400
Skin and soft tissues 99 | 17,230
Blood and immune system 98 | 16,909
Liver and Pancreas 97 | 16,750
Urinary Tract 96 | 16,678
Nervous System 94 | 16,725
Respiratory system 93 | 16,393
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 95 | 12,091
Enzyme 10 | 4,145

PANTHER Protein Class (0)

calcium-binding protein 105 | 105
transcription factor 1,073 | 1,073
nucleic acid binding 1,006 | 1,006
hydrolase 762 | 762
enzyme modulator 645 | 645
transferase 625 | 625
transporter 580 | 580
signaling molecule 554 | 554
cytoskeletal protein 441 | 441
receptor 400 | 400
oxidoreductase 319 | 319
membrane traffic protein 217 | 217
cell adhesion molecule 191 | 191
ligase 191 | 191
defense/immunity protein 177 | 177
extracellular matrix protein 175 | 175
transfer/carrier protein 175 | 175
cell junction protein 90 | 90
chaperone 89 | 89
isomerase 84 | 84
lyase 64 | 64
transmembrane receptor regulat... 64 | 64
structural protein 45 | 45
storage protein 18 | 18
surfactant 8 | 8
viral protein 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Calpain-14 CAPN14 Tdark Non-IDG -0.55232 4.56 19
EF-hand domain-containing protein D1 EFHD1 Tbio Non-IDG -1.96673 92.2 187
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.18033 15.0 36
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Myosin regulatory light chain 2, atrial isoform MYL7 Tbio Non-IDG -0.85198 5.20 169
Epidermal growth factor-like protein 7 EGFL7 Tbio Non-IDG -1.78690 72.8 217
Putative teratocarcinoma-derived growth factor 3 TDGF1P3 Tdark Non-IDG -1.99746 160.4 0
Calpain-12 CAPN12 Tdark Non-IDG -0.45780 3.51 74
Cell division cycle and apoptosis regulator protein 1 CCAR1 Tbio Non-IDG -3.01156 1013.4 123